Lulla Opatowski

Lulla Opatowski is professor in Mathematical Epidemiology (University of Versailles Saint Quentin – UVSQ).

My main research interests are in mathematical modelling of infectious disease and statistical inference, with a particular interest in bacterial resistance to antimicrobials (including antibiotics and vaccines) and host-pathogen-pathogen interactions. My main projects include:

• Pathogens interactions: Modelling between-pathogen interactions within the respiratory tract, in particular virus-virus and virus-bacteria interactions, such as those between Streptococcus pneumoniae and respiratory viruses (Influenza, RSV and other respiratory viruses).
• Microbiome and pathogens acquisition: Building models to study the dynamic of microbiota and the potential factors leading to the acquisition of pathogens and specifically antibiotic resistant bacteria
• Nosocomial / health-care associated infections: modelling analysis of antibiotic-resistant bacteria in hospitals. This includes both theoretical models and the analysis of strains transmission routes from detailed proximity contact data and colonisation of S. aureus and Enterobacteriales
• Transmission of antibiotic resistant bacteria in households: We use models to track  the transmission of bacterial strains and resistance genes between individuals in households in France and Madagascar
• One health dissemination of AMR: Modelling selection, persistence and transmission of antibiotic resistance genes and species in different reservoirs and across them (effluents, animals, humans)
• Impact of vaccination: study of multi-strain models (pneumococcus and HPV) and impact of vaccines on antibiotic resistance
• Respiratory viruses, including SARS-COV-2: we analyse the risk of transmission of the virus in populations with a particular focus on small populations such as health care settings (within patients and health care worker) or households

Team members:

• Maria Alexa
• Sophie Chervet
• Aleksandra Kovacevic
• Maylis Layan
• Taeyong Lee
• Aurélie Maurin (Le Cnam)
• Camille Schneider
• Jérémy Seurat

Former team members:

• Hélène Arduin, PhD student
• Rania Assab, PhD student
• Jonathan Bastard, PhD student
• Mélanie Bonneault, PhD student
• Auguste Caen, Postdoc
• Matthieu Domenech de Celles, Postdoc
• Audrey Duval, PhD student
• Xuefeng Gao, Postdoc
• Pachka Hammami, Postdoc
• Thomas Haschka, Postdoc
• Paul Henriot, Engineer
• Nathanaël Hoze, Postdoc
• Quentin Leclerc, Postdoc
• Romain Narci, Postdoc
• Ajmal Oodally, Postdoc
• Eve Rahbé, PhD student
• George Shirreff, Postdoc
• David Smith, PhD student

ACADEMIC BACKGROUND
2018                HDR in Biomathematics - Habilitation à diriger des recherches, Paris Saclay University, UVSQ
2005 – 2009         PhD in Biomathematics - Public Health: Epidemiology and science of biomedical information. University Pierre and Marie Curie, Paris VI, ED 393.
2000 – 2003         Engineer ENSIMAG (Graduate School of Engineering in Applied Mathematics and Computer Science, French equivalent for Master of Computer Science and Applied Mathematics) –  Grenoble, France
2002 – 2003         Licenciatura in University of mathematics and statistics (5th year) member of UPC (Universitat Politécnica de Catalunya), Barcelona, Spain
1997 – 2000 Special intensive courses of advanced mathematics and physics (undergraduate level)  

LABS
- 2012-.  Assistant professor > Professor. Versailles Saint Quentin University, EMEA unit UMR1018, Institut Pasteur / INSERM /UVSQ, France. 
- 2009-12 Research Associate (POST DOC). MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College, London. 
- 2005–09 Institut Pasteur / U657 INSERM, Pharmaco-Epidemiology applied to Infectious Diseases laboratory (PhEMI)
- 2003–04 CRG (Centre of Genomic Regulation), Microarrays Laboratory and GRIB (Group of Research in Bio-medicine and Computer Science), Chemogenomics Laboratory – Barcelona, Spain