Lulla Opatowski

Neonatal acquisition of ESBL-PE in the community of a Low-Income Country  Severe bacterial infections are a leading cause of neonatal deaths, with low income countries (LICs) bearing the highest burden. In LICs, neonatal bacterial […]

Project MOD-COV (Modelling of the hOspital Dissemination of SARS-CoV-2) In the context of SARS-CoV-2 pandemic, healthcare institutions are confronted to major challenges. First the community spread is leading to a large demand in available […]

Cliquer ici pour aller à l’enquête Confinement, mesures barrières, limitation des rassemblements etc. Les mesures de prévention actuellement mises en place sont inédites. Elles ont fondamentalement modifié les contacts que nous avons au quotidien. […]

Healthcare-associated infections (HAI) have been occurring with increased incidence and severity over the last decades, becoming a major public health issue. A wide range of control strategies is already available, including hygiene measures, barrier […]

Our group is in charge of the modelling workpackage of the Pandore project (Prédiction de l’ANtibiorésistance dans Des zOnes anthRopisées Environnementales), which aims at investigating the dynamics of antibiotic resistance genes in waters and […]

The main objective of the SARAH project is to study the determinants of antibiotic resistant bacteria dissemination at the animal-human interface. We develop a methodological research based on mathematical modelling and the analysis of […]

Klebsiella pneumoniae (hereafter, K. pneumoniae) is a major cause of hospital-acquired infections such as urinary infections, pneumonia, bloodstream infections, infections in newborns and in intensive-care unit patients. Some hypervirulent strains also cause community infections […]

Despite advances in modern biology and medicine, antibiotic-resistant bacteria (ARB) have spread in the community and in hospitals over the last decades, becoming a major public health problem. Mathematical modeling and computer simulations are […]

Invasive pneumococcal diseases (IPDs) are a major cause of morbidity and mortality worldwide. The mechanisms responsible for the epidemiological patterns of susceptible- and resistant- IPDs which include a yearly winter peak are still poorly […]

The i-Bird program was devoted to explore the ability of MRSA and ER3GC to disseminate within hospital clinical departments. This program involved tracing the clonal dissemination of MRSA and ER3GC among hospitalized patients and […]

Acquisition of antibiotic resistant bacteria and development of the gut microbiome in neonates in low-income countries. Antibiotic resistance represents a major health issue worldwide. The situation is particularly acute in low-income countries (LIC), due […]

Children’s Antibiotic Resistance colonization and Route of Transmission. The aim of this program is to assess the transmission of enterobacteria resistant to 3rd generation cephalosporines (EBRCIIIG) in hospitalized neonates in two low income countries […]

In addition to a direct effect on the individual, the consumption of antiinfective drugs may have an indirect ecological benefit only visible at the population level. Moreover indirect ecological adverse effects may also exist […]

Statistical and Mathematical Modeling in Biological Applications — SaMMBA The seminar series Statistical and Mathematical Modeling in Biological Applications (SaMMBA) features monthly lectures and discussions with leading modelers in biological sciences. Presentations are in English or […]