Phylogenomics of Shiga’s epidemic dysentery bacillus (Shigella dysenteriae type 1)
The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]
Evolution of the Pathogenicity Locus of C. difficile
The major virulence factors of Clostridium difficile are toxins A and B. These toxins are encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with three additional genes that have been […]
Genetic variability of non-segmented negative RNA virus populations and host adaptation (Viva&Host)
Non-segmented negative strand RNA viruses are characterized by an intrinsic genome instability, the result of an error-prone RNA dependant RNA polymerase. To date, most viral populations have been characterized by their consensus genome sequences. […]
Sequana: a set of flexible NGS pipelines
Sequana is a Python framework designed to provide pipelines to analyse Next Generation Sequencing data sets. Sequana provides tools to access the sequence quality but also post-processing analysis such as depth of coverage or […]
2019Genomic insights into the 2016-2017 cholera epidemic in Yemen, Nature 2019 Jan;.
2018Sequana Coverage: Detection and Characterization of Genomic Variations using Running Median and Mixture Models, GigaScience, giy110, https://doi.org/10.1093/gigascience/giy110.
2018Generating genomic platforms to study Candida albicans pathogenesis, Nucleic Acids Res. 2018 Aug;46(14):6935-6949.
2018Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity, Genome Biol Evol 2018 Jul;.
2018Gene flow contributes to diversification of the major fungal pathogen Candida albicans, Nat Commun 2018 Jun;9(1):2253.
2018Sequanix: A Dynamic Graphical Interface for Snakemake Workflows, https://doi.org/10.1093/bioinformatics/bty034.
2017Characterization of Clostridium Baratii Type F Strains Responsible for an Outbreak of Botulism Linked to Beef Meat Consumption in France, PLOS Currents Outbreaks. 2017 Feb 1 . Edition 1. doi: 10.1371/currents.outbreaks.6ed2fe754b58a5c42d0c33d586ffc606..
2017Resistance to thiacetazone derivatives active against Mycobacterium abscessus involves mutations in the MmpL5 transcriptional repressor MAB_4384, Antimicrob. Agents Chemother. 2017 Jan;.
2016A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study, Lancet Infect Dis 2017 Feb;17(2):174-183.
2016Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria, Proc. Natl. Acad. Sci. U.S.A. 2016 Aug;.
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