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Projects

project
Completed
16 Members

Phylogenomics of Shiga’s epidemic dysentery bacillus (Shigella dysenteriae type 1)

Francois-Xavier Weill (PI)

The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]
project
Completed
7 Members

Evolution of the Pathogenicity Locus of C. difficile

Bruno Dupuy (PI)

The major virulence factors of Clostridium difficile are toxins A and B. These toxins are encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with three additional genes that have been […]
project
Ongoing
5 Members

Genetic variability of non-segmented negative RNA virus populations and host adaptation (Viva&Host)

Hervé Bourhy (PI)

Non-segmented negative strand RNA viruses are characterized by an intrinsic genome instability, the result of an error-prone RNA dependant RNA polymerase. To date, most viral populations have been characterized by their consensus genome sequences. […]

Publications

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