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Evolution of the Pathogenicity Locus of C. difficile
Bruno Dupuy (PI)
The major virulence factors of Clostridium difficile are toxins A and B. These toxins are encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with three additional genes that have been […]
2018Generating genomic platforms to study Candida albicans pathogenesis, Nucleic Acids Res. 2018 Aug;46(14):6935-6949.
2018Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity, Genome Biol Evol 2018 Jul;.
2018Gene flow contributes to diversification of the major fungal pathogen Candida albicans, Nat Commun 2018 Jun;9(1):2253.
2016Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria, Proc. Natl. Acad. Sci. U.S.A. 2016 Aug;.
2016Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes, Genome Biol Evol 2016 06;8(6):1643-60.
2016Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes, Malar. J. 2016 Apr;15:206.
2016Demography and Intercontinental Spread of the USA300 Community-Acquired Methicillin-Resistant Staphylococcus aureus Lineage, MBio 2015;7(1).
2016pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence, Nature Microbiol. 1, 15019 (2016).
2015Draft Genome Sequences of Acinetobacter parvus CM11, Acinetobacter radioresistens CM38, and Stenotrophomonas maltophilia BR12, Isolated from Murine Proximal Colonic Tissue, Genome Announc 2015;3(5).
2015Clostridium difficile: New Insights into the Evolution of the Pathogenicity Locus, Sci Rep 2015;5:15023.
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