Carmen Buchrieser

5 Members

From the source to the user end: deciphering the impact of microbiome and water parameters on opportunistic waterborne pathogens (MicroPathWater)

Laura Gomez Valero (PI)

7 Members

Deciphering the virulence of Legionella pneumophila in vivo in the zebrafish model (ZebraLegion)

L. pneumophila -host interactions have been studied in several animal models, but they all have their weaknesses and except the guinea pig model that is rarely used, they do not well recall human infection. […]

2 Members

Investigation how eukaryotic domain capture might work: the evolution of a bacterial effector

Legionella pneumophila is a gram-negative environmental intracellular bacterium which causes a severe pneumonia. It survives and replicates in the environment in protozoa and during human infection in alveolar macrophages. This is achieved by a […]

3 Members

Biogenesis, trafficking, and roles of Legionella pneumophila extracellular vesicles during infection (BioEV)

Extracellular vesicles (EVs), produced by eukaryotes, bacteria and archaea are increasingly recognized as important mediators of intercellular communication via transfer of a wide variety of molecular cargoes. Recently EVs of several intracellular pathogens have […]

6 Members

TheraEPI

Paola Arimondo (PI)

A common phenomenon in most microbial infections is the attenuation of the host’s immediate immune response, allowing for long-term colonization. We and others have shown that many pathogens achieve this by manipulating the epigenetic […]

1 Member

Molecular, genetic and cellular basis of the infection by Legionella