Timeline

Elisabeth Menu

Group Leader

15 Feb 2023

project

FEMIN

01 Jan 2022

publication

Women for science and science for women: Gaps, challenges and opportunities towards optimizing pre-exposure prophylaxis for HIV-1 prevention.

01 Jan 2022

publication

A Case Study to Dissect Immunity to SARS-CoV-2 in a Neonate Nonhuman Primate Model.

01 Jan 2022

publication

Role of the human vaginal microbiota in the regulation of inflammation and sexually transmitted infection acquisition: Contribution of the non-human primate model to a better understanding?

01 Jan 2022

publication

Local Innate Markers and Vaginal Microbiota Composition Are Influenced by Hormonal Cycle Phases.

01 Jun 2021

publication

Neonatal Immune System Ontogeny: The Role of Maternal Microbiota and Associated Factors. How Might the Non-Human Primate Model Enlighten the Path?

12 Jun 2019

publication

Dynamics of Vaginal and Rectal Microbiota Over Several Menstrual Cycles in Female Cynomolgus Macaques

12 Mar 2019

publication

Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae.

31 Jul 2017

publication

Modified Vaccinia Virus Ankara Vector Induces Specific Cellular and Humoral Responses in the Female Reproductive Tract, the Main HIV Portal of Entry.

06 Jun 2016

publication

NK cells control HIV-1 infection of macrophages through soluble factors and cellular contacts in the human decidua

09 Sep 2015

publication

The local environment orchestrates mucosal decidual macrophage differentiation and substantially inhibits HIV-1 replication

16 Jul 2015

team

Group: MISTIC

04 Jul 2015

project

Mucosal Immunity and Sexually Transmitted Infection Control (MISTIC)

12 Nov 2014

publication

Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1.

01 Jul 2014

publication

Human decidual macrophages and NK cells differentially express Toll-like receptors and display distinct cytokine profiles upon TLR stimulation

05 Jan 2012

publication

Dynamic shift from CD85j/ILT-2 to NKG2D NK receptor expression pattern on human decidual NK during the first trimester of pregnancy

18 Jul 2011

publication

Decidual soluble factors participate in the control of HIV-1 infection at the maternofetal interface

02 Dec 2009

publication

Plasmodium falciparum infection significantly impairs placental cytokine profile in HIV infected Cameroonian women

22 Jun 2009

publication

Antigen-presenting cells represent targets for R5 HIV-1 infection in the first trimester pregnancy uterine mucosa

15 May 2009

publication

Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells

01 Mar 2009

publication

Higher placental anti-inflammatory IL-10 cytokine expression in HIV-1 infected women receiving longer zidovudine prophylaxis associated with nevirapine

30 Dec 2008

publication

In vitro and in vivo human herpesvirus 8 infection of placenta

31 Mar 2008

publication

Distinct efficacy of HIV-1 entry inhibitors to prevent cell-to-cell transfer of R5 and X4 viruses across a human placental trophoblast barrier in a reconstitution model in vitro

30 Mar 2008

publication

Specific stimulation of HIV-1 replication in human placental trophoblasts by an antigen of Plasmodium falciparum

18 May 2007

publication

Characterization of the main placental cytokine profiles from HIV-1-infected pregnant women treated with anti-retroviral drugs in France

23 Jun 2006

publication

Tumour necrosis factor-alpha stimulates HIV-1 replication in single-cycle infection of human term placental villi fragments in a time, viral dose and envelope dependent manner

22 Jun 2006

publication

A natural CCL5/RANTES variant antagonist for CCR1 and CCR3

01 Jun 2006

publication

HIV-1 pol gene polymorphism and antiretroviral resistance mutations in drug-naive pregnant women in Yaoundé, Cameroon

13 Dec 2005

publication

Down modulation of TNF-alpha mRNA placental expression by AZT used for the prevention of HIV-1 mother-to-child transmission

01 Oct 2005

publication

Impact of the placental cytokine-chemokine balance on regulation of cell-cell contact-induced human immunodeficiency virus type 1 translocation across a trophoblastic barrier in vitro

06 Apr 2005

publication

First Dominique Dormont International Conference on “Host-pathogen interactions in chronic infections – viral and host determinants of HCV, HCMV, and HIV infections”.

01 Feb 2005

publication

Evaluation of the placental environment with a new in vitro model of histocultures of early and term placentae: determination of cytokine and chemokine expression profiles

01 Jul 2004

publication

Human immunodeficiency virus 1 downregulates cell surface expression of the non-classical major histocompatibility class I molecule HLA-G1

01 Jun 2004

publication

[Prevention of mother to child HIV-1 transmission (MTC) in Cameroon]

01 Mar 2004

publication

Evaluation of Cytokeratin 7 as an accurate intracellular marker with which to assess the purity of human placental villous trophoblast cells by flow cytometry

01 Nov 2003

publication

Low rate of mother-to-child transmission of HIV-1 after nevirapine intervention in a pilot public health program in Yaoundé, Cameroon

01 Nov 2003

publication

Mother-to-child transmission of HIV: developing integration of healthcare programmes with clinical, social and basic research studies. Report of the International Workshop held at Chobe Marina Lodge, Kasane, Botswana, 21-25 January 2003

01 Oct 2003

publication

Cell-free HIV type 1 infection is restricted in the human trophoblast choriocarcinoma BeWo cell line, even with expression of CD4, CXCR4 and CCR5

01 Oct 2003

publication

Predominant intracellular expression of CXCR4 and CCR5 in purified primary trophoblast cells from first trimester and term human placentae

01 Oct 2003

publication

Mother-to-child transmission of human immunodeficiency virus type 1 in relation to the season in Yaounde, Cameroon

01 Nov 2001

publication

Expression of beta chemokines in explants and trophoblasts from early and term human placentae

01 Sep 2001

publication

Placental cytokine and chemokine production in HIV-1-infected women: trophoblast cells show a different pattern compared to cells from HIV-negative women

01 May 2001

publication

Cell-to-cell contact results in a selective translocation of maternal human immunodeficiency virus type 1 quasispecies across a trophoblastic barrier by both transcytosis and infection

01 Sep 2000

publication

Evidence of the existence of a new circulating recombinant form of HIV type 1 subtype A/J in Cameroon. The European Network on the Study of In Utero Transmission of HIV-1

01 May 2000

publication

Coreceptor usage of HIV-1 isolates representing different genetic subtypes obtained from pregnant Cameroonian women. European Network for In Utero Transmission of HIV-1

01 Mar 2000

publication

HIV-1 co-receptor expression on trophoblastic cells from early placentas and permissivity to infection by several HIV-1 primary isolates

20 Nov 1999

publication

An unusual HIV type 1 env sequence embedded in a mosaic virus from Cameroon: identification of a new env clade. European Network on the study of in utero transmission of HIV-1

01 May 1999

publication

Vertical transmission of HIV: parameters which might affect infection of placental trophoblasts by HIV-1: a review. Biomed Group on the Study of in Utero Transmission of HIV 1

15 Apr 1999

publication

Predominance of CCR5-dependent HIV-1 subtype E isolates in Cambodia.

01 Jan 1999

publication

Selection of maternal human immunodeficiency virus type 1 variants in human placenta. European Network for In Utero Transmission of HIV-1

01 Nov 1998

publication

Introduction of HIV-1 subtype A in the French West Indies.

01 Jul 1998

publication

HIV type 1 diversity and the reliability of the heteroduplex mobility assay

01 Jun 1998

publication

High incidence of early postnatal transmission of human immunodeficiency virus type 1 in Bangui, Central African Republic

01 Dec 1997

publication

Insights into the mechanisms of vertical transmission of HIV-1. BIOMED2 Working Group on the in utero transmission of HIV-1

01 Sep 1997

publication

Induction of transient murine T cell anergy by a low molecular weight compound obtained from supernatants of human placental cultures is linked to defective phosphorylation of TCR CD3 chain

01 Jun 1997

publication

Immune suppression and Th1/Th2 balance in pregnancy revisited: a (very) personal tribute to Tom Wegmann

01 Feb 1997

publication

Immunoactive products of placenta. VI. Induction of transient murine T cell anergy by a low-molecular-weight compound obtained from supernatants of human placental cultures

01 Jan 1997

publication

Immunopathology of early pregnancy

01 Jan 1997

publication

Maternal T cell reactivity in pregnancy?

01 Jan 1997

publication

[Tumor necrosis factor and induced labor]

01 Jul 1996

publication

Immunoactive products of placenta. V. Immunoregulatory properties of a low molecular weight compound obtained from human placental cultures

01 May 1996

publication

HIV type 1 Thai subtype E is predominant in South Vietnam.

01 Apr 1996

publication

The emerging role of IL-10 in pregnancy

01 Dec 1995

publication

Immuno-endocrine interactions in early pregnancy

20 Apr 1995

publication

HIV infection of choriocarcinoma cell lines derived from human placenta: the role of membrane CD4 and Fc-Rs into HIV entry

01 Feb 1995

publication

Alloimmunization against well defined polymorphic major histocompatibility or class I MHC transfected L cells antigens can prevent poly IC induced fetal death in mice

15 Sep 1994

publication

CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation

26 Jun 1992

publication

Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59

01 Apr 1992

publication

Human trophoblast cells express CD4 and are permissive for productive infection with HIV-1

01 Dec 1991

publication

In vitro and in vivo immunosuppressive effects of supernatants from human choriocarcinoma cell lines

01 Sep 1991

publication

Immunoactive products of human placenta. IV. Immunoregulatory factors obtained from cultures of human placenta inhibit in vivo local and systemic allogeneic and graft versus-host reactions in mice

01 Jul 1990

publication

Control of fetal survival in CBA x DBA/2 mice by lymphokine therapy

01 Feb 1990

publication

Immunologically mediated abortions: one or several pathways?

01 Jan 1990

publication

Immunoactive products of human placenta (III): Characterization of an inhibitor affecting lymphocyte proliferation

01 Nov 1989

publication

Immunoactive products of human placenta. II. Direct inhibition of non-MHC restricted cytolytic activity of human CD3 alpha-beta but not CD3 gamma-delta expressing T cell clones

01 Aug 1989

publication

Immunological manipulations in animal pregnancy and models of pregnancy failure

01 Apr 1989

publication

Immunoactive products of human placenta. I. An immunoregulatory factor obtained from explant cultures of human placenta inhibits CTL generation and cytotoxic effector activity

01 Feb 1989

publication

The role of M-CSF and GM-CSF in fostering placental growth, fetal growth, and fetal survival

01 Nov 1988

publication

Maternal T cells regulate placental size and fetal survival

01 Jan 1988

publication

A little guide for advanced search:

FEMIN

Women for science and science for women: Gaps, challenges and opportunities towards optimizing pre-exposure prophylaxis for HIV-1 prevention.

A Case Study to Dissect Immunity to SARS-CoV-2 in a Neonate Nonhuman Primate Model.

Role of the human vaginal microbiota in the regulation of inflammation and sexually transmitted infection acquisition: Contribution of the non-human primate model to a better understanding?

Local Innate Markers and Vaginal Microbiota Composition Are Influenced by Hormonal Cycle Phases.

Neonatal Immune System Ontogeny: The Role of Maternal Microbiota and Associated Factors. How Might the Non-Human Primate Model Enlighten the Path?

Dynamics of Vaginal and Rectal Microbiota Over Several Menstrual Cycles in Female Cynomolgus Macaques

Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae.

Modified Vaccinia Virus Ankara Vector Induces Specific Cellular and Humoral Responses in the Female Reproductive Tract, the Main HIV Portal of Entry.

NK cells control HIV-1 infection of macrophages through soluble factors and cellular contacts in the human decidua

The local environment orchestrates mucosal decidual macrophage differentiation and substantially inhibits HIV-1 replication

Group: MISTIC

Mucosal Immunity and Sexually Transmitted Infection Control (MISTIC)

Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1.

Human decidual macrophages and NK cells differentially express Toll-like receptors and display distinct cytokine profiles upon TLR stimulation

Dynamic shift from CD85j/ILT-2 to NKG2D NK receptor expression pattern on human decidual NK during the first trimester of pregnancy

Decidual soluble factors participate in the control of HIV-1 infection at the maternofetal interface

Plasmodium falciparum infection significantly impairs placental cytokine profile in HIV infected Cameroonian women

Antigen-presenting cells represent targets for R5 HIV-1 infection in the first trimester pregnancy uterine mucosa

Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells

Higher placental anti-inflammatory IL-10 cytokine expression in HIV-1 infected women receiving longer zidovudine prophylaxis associated with nevirapine

In vitro and in vivo human herpesvirus 8 infection of placenta

Distinct efficacy of HIV-1 entry inhibitors to prevent cell-to-cell transfer of R5 and X4 viruses across a human placental trophoblast barrier in a reconstitution model in vitro

Specific stimulation of HIV-1 replication in human placental trophoblasts by an antigen of Plasmodium falciparum

Characterization of the main placental cytokine profiles from HIV-1-infected pregnant women treated with anti-retroviral drugs in France

Tumour necrosis factor-alpha stimulates HIV-1 replication in single-cycle infection of human term placental villi fragments in a time, viral dose and envelope dependent manner

A natural CCL5/RANTES variant antagonist for CCR1 and CCR3

HIV-1 pol gene polymorphism and antiretroviral resistance mutations in drug-naive pregnant women in Yaoundé, Cameroon

Down modulation of TNF-alpha mRNA placental expression by AZT used for the prevention of HIV-1 mother-to-child transmission

Impact of the placental cytokine-chemokine balance on regulation of cell-cell contact-induced human immunodeficiency virus type 1 translocation across a trophoblastic barrier in vitro

First Dominique Dormont International Conference on “Host-pathogen interactions in chronic infections – viral and host determinants of HCV, HCMV, and HIV infections”.

Evaluation of the placental environment with a new in vitro model of histocultures of early and term placentae: determination of cytokine and chemokine expression profiles

Human immunodeficiency virus 1 downregulates cell surface expression of the non-classical major histocompatibility class I molecule HLA-G1

[Prevention of mother to child HIV-1 transmission (MTC) in Cameroon]

Evaluation of Cytokeratin 7 as an accurate intracellular marker with which to assess the purity of human placental villous trophoblast cells by flow cytometry

Low rate of mother-to-child transmission of HIV-1 after nevirapine intervention in a pilot public health program in Yaoundé, Cameroon

Mother-to-child transmission of HIV: developing integration of healthcare programmes with clinical, social and basic research studies. Report of the International Workshop held at Chobe Marina Lodge, Kasane, Botswana, 21-25 January 2003

Cell-free HIV type 1 infection is restricted in the human trophoblast choriocarcinoma BeWo cell line, even with expression of CD4, CXCR4 and CCR5

Predominant intracellular expression of CXCR4 and CCR5 in purified primary trophoblast cells from first trimester and term human placentae

Mother-to-child transmission of human immunodeficiency virus type 1 in relation to the season in Yaounde, Cameroon

Expression of beta chemokines in explants and trophoblasts from early and term human placentae

Placental cytokine and chemokine production in HIV-1-infected women: trophoblast cells show a different pattern compared to cells from HIV-negative women

Cell-to-cell contact results in a selective translocation of maternal human immunodeficiency virus type 1 quasispecies across a trophoblastic barrier by both transcytosis and infection

Evidence of the existence of a new circulating recombinant form of HIV type 1 subtype A/J in Cameroon. The European Network on the Study of In Utero Transmission of HIV-1

Coreceptor usage of HIV-1 isolates representing different genetic subtypes obtained from pregnant Cameroonian women. European Network for In Utero Transmission of HIV-1

HIV-1 co-receptor expression on trophoblastic cells from early placentas and permissivity to infection by several HIV-1 primary isolates

An unusual HIV type 1 env sequence embedded in a mosaic virus from Cameroon: identification of a new env clade. European Network on the study of in utero transmission of HIV-1

Vertical transmission of HIV: parameters which might affect infection of placental trophoblasts by HIV-1: a review. Biomed Group on the Study of in Utero Transmission of HIV 1

Predominance of CCR5-dependent HIV-1 subtype E isolates in Cambodia.

Selection of maternal human immunodeficiency virus type 1 variants in human placenta. European Network for In Utero Transmission of HIV-1

Introduction of HIV-1 subtype A in the French West Indies.

HIV type 1 diversity and the reliability of the heteroduplex mobility assay

High incidence of early postnatal transmission of human immunodeficiency virus type 1 in Bangui, Central African Republic

Insights into the mechanisms of vertical transmission of HIV-1. BIOMED2 Working Group on the in utero transmission of HIV-1

Induction of transient murine T cell anergy by a low molecular weight compound obtained from supernatants of human placental cultures is linked to defective phosphorylation of TCR CD3 chain

Immune suppression and Th1/Th2 balance in pregnancy revisited: a (very) personal tribute to Tom Wegmann

Immunoactive products of placenta. VI. Induction of transient murine T cell anergy by a low-molecular-weight compound obtained from supernatants of human placental cultures

Immunopathology of early pregnancy

Maternal T cell reactivity in pregnancy?

[Tumor necrosis factor and induced labor]

Immunoactive products of placenta. V. Immunoregulatory properties of a low molecular weight compound obtained from human placental cultures

HIV type 1 Thai subtype E is predominant in South Vietnam.

The emerging role of IL-10 in pregnancy

Immuno-endocrine interactions in early pregnancy

HIV infection of choriocarcinoma cell lines derived from human placenta: the role of membrane CD4 and Fc-Rs into HIV entry

Alloimmunization against well defined polymorphic major histocompatibility or class I MHC transfected L cells antigens can prevent poly IC induced fetal death in mice

CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation

Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59

Human trophoblast cells express CD4 and are permissive for productive infection with HIV-1

In vitro and in vivo immunosuppressive effects of supernatants from human choriocarcinoma cell lines

Immunoactive products of human placenta. IV. Immunoregulatory factors obtained from cultures of human placenta inhibit in vivo local and systemic allogeneic and graft versus-host reactions in mice

Control of fetal survival in CBA x DBA/2 mice by lymphokine therapy

Immunologically mediated abortions: one or several pathways?

Immunoactive products of human placenta (III): Characterization of an inhibitor affecting lymphocyte proliferation

Immunoactive products of human placenta. II. Direct inhibition of non-MHC restricted cytolytic activity of human CD3 alpha-beta but not CD3 gamma-delta expressing T cell clones

Immunological manipulations in animal pregnancy and models of pregnancy failure

Immunoactive products of human placenta. I. An immunoregulatory factor obtained from explant cultures of human placenta inhibits CTL generation and cytotoxic effector activity

The role of M-CSF and GM-CSF in fostering placental growth, fetal growth, and fetal survival

Maternal T cells regulate placental size and fetal survival