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© Charles Dauguet
Virus VIH-1 (HIV-1), agent du sida, à la surface d'un lymphocyte. Image colorisée.
Publication : American journal of reproductive immunology (New York, N.Y. : 1989)

Immunoactive products of placenta. V. Immunoregulatory properties of a low molecular weight compound obtained from human placental cultures

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in American journal of reproductive immunology (New York, N.Y. : 1989) - 01 Jul 1996

Djian V, Menu E, Thibault G, Ropert S, Chaouat G

Link to Pubmed [PMID] – 8831897

Am. J. Reprod. Immunol. 1996 Jul;36(1):11-24

We have previously shown that supernatants from short-term cultures of human placental explants (HPS) are immunosuppressive in vitro as well as in vivo. They contain a low M.W. factor endowed with immunoregulatories activities (Filtrate of such with a 5 kDa cut off). In this paper, we wanted to assess whether this low M.W. material accounts for most, if not all, of the immunosuppressive properties of crude HPS and begin to investigate its mode of action.