Timeline

Nienke Buddelmeijer

Group Leader

12 Jul 2024

event

3rd Drug Discovery & Screening Symposium – “Innovative Therapeutics: Small Molecules and Biologics in Modern Medicine” – an ATC-DDS initiative

07 Nov 2023

publication

Components Subcellular Localization: Identification of Lipoproteins Using Alkyne Fatty Acids and Click Chemistry

07 Nov 2023

publication

Components Subcellular Localization: Identification of Lipoproteins Using Globomycin and Radioactive Palmitate

27 Oct 2023

event

ATC-DDS Seminar – “Epigenetic regulation: at the apex of Innate Immune Memory” – Pr. Musa M. Mhlanga (Radboud University, Netherlands)

13 Jul 2023

event

2nd Drug Discovery & Screening Symposium – “From bench to drug discovery” – an ATC-DDS initiative

20 Sep 2022

publication

A Defect in Lipoprotein Modification by Lgt Leads to Abnormal Morphology and Cell Death in Escherichia coli That Is Independent of Major Lipoprotein Lpp

29 Aug 2022

program_project

Drug Discovery & Screening at Institut Pasteur

20 Jan 2022

team

U1306 – Host-Microbe interactions and pathophysiology

01 Mar 2021

publication

Mode of action of lipoprotein modification enzymes—Novel antibacterial targets

01 Jan 2021

publication

Editorial : Post-translational modifications in bacteria – The dynamics of bacterial physiology

13 May 2020

publication

Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening

04 Nov 2019

publication

A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt)

18 Sep 2018

event

Department of Microbiology and Department of Structural Biology & Chemistry : “Structure and function of the type 6 secretion system, a bacterial weapon of mass destruction”, by Chiara RAPISARDA

04 Jul 2017

publication

Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.

02 Jan 2017

project

Inhibition of peptidoglycan assembly complexes

01 Jan 2017

publication

Identification of Lipoproteins Using Globomycin and Radioactive Palmitate.

24 Feb 2016

team

Group : Cell Shape and Pathogenicity

02 Jul 2015

project

Biology and Genetics of Bacterial Cell Wall

11 May 2015

team

Biology and Genetics of Bacterial Cell Wall

10 Feb 2015

publication

The molecular mechanism of bacterial lipoprotein modification–how, when and why?

16 Jan 2015

publication

Residues located on membrane-embedded flexible loops are essential for the second step of the apolipoprotein N-acyltransferase reaction

01 Jan 2015

publication

Substituted Cysteine Accessibility Method for Topology and Activity Studies of Membrane Enzymes Forming Thioester Acyl Intermediates in Bacteria

01 Jan 2013

publication

Institut Pasteur Minisymposium on Bacterial Membranes 2013

01 Jan 2013

publication

Immunolabeling of Proteins in situ in Escherichia coli K12 Strains

01 Nov 2012

publication

Getting in touch: microbial molecular devices for cell-cell and cell-surface interactions

30 Mar 2012

publication

N-acylation of lipoproteins: not when sour.

27 Jan 2012

publication

Phosphatidylglycerol::Prolipoprotein Diacylglyceryl Transferase (Lgt) of Escherichia coli Has Seven Transmembrane Segments, and Its Essential Residues Are Embedded in the Membrane

01 Jan 2012

publication

Getting in touch: microbial molecular devices for cell-cell and cell-surface interactions

15 Jun 2011

publication

Kinetics and phospholipid specificity of apolipoprotein N-acyltransferase.

19 Jan 2010

publication

The Essential Escherichia coli Apolipoprotein N -Acyltransferase (Lnt) Exists as an Extracytoplasmic Thioester Acyl-Enzyme Intermediate

31 Oct 2008

publication

Type II secretion system secretin PulD localizes in clusters in the Escherichia coli outer membrane.

06 Apr 2007

publication

Identification of Essential Residues in Apolipoprotein N -Acyl Transferase, a Member of the CN Hydrolase Family

08 Dec 2006

publication

Signal recognition particle-dependent inner membrane targeting of the PulG Pseudopilin component of a type II secretion system.

01 Apr 2006

publication

Green Fluorescent Chimeras Indicate Nonpolar Localization of Pullulanase Secreton Components PulL and PulM

01 Apr 2006

publication

Green fluorescent chimeras indicate nonpolar localization of pullulanase secreton components PulL and PulM

01 Sep 2004

publication

Traffic spotting: poles apart

01 Jun 2004

publication

A complex of the Escherichia coli cell division proteins FtsL, FtsB and FtsQ forms independently of its localization to the septal region

01 Dec 2002

publication

Assembly of cell division proteins at the E. coli cell center

23 Apr 2002

publication

YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site

01 Sep 1999

publication

Timing of FtsZ assembly in Escherichia coli

01 Dec 1998

publication

Localization of cell division protein FtsQ by immunofluorescence microscopy in dividing and nondividing cells of Escherichia coli

01 Apr 1998

publication

The structure and function of Escherichia coli penicillin-binding protein 3

01 Jan 1994

publication

Analysis of a novel DNA-binding protein kinase CKII-like enzyme of Chironomus cells

01 Dec 1993

publication

A majority of casein kinase II alpha subunit is tightly bound to intranuclear components but not to the beta subunit

21 Dec 1992

publication

A novel nuclear 42-kDa casein kinase identified in Chironomus tentans

25 May 1992

publication

A little guide for advanced search:

3rd Drug Discovery & Screening Symposium – “Innovative Therapeutics: Small Molecules and Biologics in Modern Medicine” – an ATC-DDS initiative

Components Subcellular Localization: Identification of Lipoproteins Using Alkyne Fatty Acids and Click Chemistry

Components Subcellular Localization: Identification of Lipoproteins Using Globomycin and Radioactive Palmitate

ATC-DDS Seminar – “Epigenetic regulation: at the apex of Innate Immune Memory” – Pr. Musa M. Mhlanga (Radboud University, Netherlands)

2nd Drug Discovery & Screening Symposium – “From bench to drug discovery” – an ATC-DDS initiative

A Defect in Lipoprotein Modification by Lgt Leads to Abnormal Morphology and Cell Death in Escherichia coli That Is Independent of Major Lipoprotein Lpp

Drug Discovery & Screening at Institut Pasteur

U1306 – Host-Microbe interactions and pathophysiology

Mode of action of lipoprotein modification enzymes—Novel antibacterial targets

Editorial : Post-translational modifications in bacteria – The dynamics of bacterial physiology

Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening

A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt)

Department of Microbiology and Department of Structural Biology & Chemistry : “Structure and function of the type 6 secretion system, a bacterial weapon of mass destruction”, by Chiara RAPISARDA

Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.

Inhibition of peptidoglycan assembly complexes

Identification of Lipoproteins Using Globomycin and Radioactive Palmitate.

Group : Cell Shape and Pathogenicity

Biology and Genetics of Bacterial Cell Wall

Biology and Genetics of Bacterial Cell Wall

The molecular mechanism of bacterial lipoprotein modification–how, when and why?

Residues located on membrane-embedded flexible loops are essential for the second step of the apolipoprotein N-acyltransferase reaction

Substituted Cysteine Accessibility Method for Topology and Activity Studies of Membrane Enzymes Forming Thioester Acyl Intermediates in Bacteria

Institut Pasteur Minisymposium on Bacterial Membranes 2013

Immunolabeling of Proteins in situ in Escherichia coli K12 Strains

Getting in touch: microbial molecular devices for cell-cell and cell-surface interactions

N-acylation of lipoproteins: not when sour.

Phosphatidylglycerol::Prolipoprotein Diacylglyceryl Transferase (Lgt) of Escherichia coli Has Seven Transmembrane Segments, and Its Essential Residues Are Embedded in the Membrane

Getting in touch: microbial molecular devices for cell-cell and cell-surface interactions

Kinetics and phospholipid specificity of apolipoprotein N-acyltransferase.

The Essential Escherichia coli Apolipoprotein N -Acyltransferase (Lnt) Exists as an Extracytoplasmic Thioester Acyl-Enzyme Intermediate

Type II secretion system secretin PulD localizes in clusters in the Escherichia coli outer membrane.

Identification of Essential Residues in Apolipoprotein N -Acyl Transferase, a Member of the CN Hydrolase Family

Signal recognition particle-dependent inner membrane targeting of the PulG Pseudopilin component of a type II secretion system.

Green Fluorescent Chimeras Indicate Nonpolar Localization of Pullulanase Secreton Components PulL and PulM

Green fluorescent chimeras indicate nonpolar localization of pullulanase secreton components PulL and PulM

Traffic spotting: poles apart

A complex of the Escherichia coli cell division proteins FtsL, FtsB and FtsQ forms independently of its localization to the septal region

Assembly of cell division proteins at the E. coli cell center

YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site

Timing of FtsZ assembly in Escherichia coli

Localization of cell division protein FtsQ by immunofluorescence microscopy in dividing and nondividing cells of Escherichia coli

The structure and function of Escherichia coli penicillin-binding protein 3

Analysis of a novel DNA-binding protein kinase CKII-like enzyme of Chironomus cells

A majority of casein kinase II alpha subunit is tightly bound to intranuclear components but not to the beta subunit

A novel nuclear 42-kDa casein kinase identified in Chironomus tentans

A cell-free extract from yeast cells for studying mRNA turnover