Ligne de temps
Bertrand Raynal
Ingénieur(e) de Recherche
13 mars 2024
publication
Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress.
Lire plus06 déc. 2023
publication
Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease.
Lire plus01 août 2023
20 juin 2023
publication
Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs.
Lire plus27 avr. 2023
22 avr. 2023
11 janv. 2023
publication
The c-di-AMP-binding protein CbpB modulates the level of ppGpp alarmone in Streptococcus agalactiae.
Lire plus01 janv. 2023
publication
Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Lire plus24 mai 2022
publication
Dengue virus NS1 protein conveys pro-inflammatory signals by docking onto high-density lipoproteins.
Lire plus01 janv. 2022
publication
Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.
Lire plus30 nov. 2021
publication
Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex.
Lire plus21 juil. 2021
publication
SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction.
Lire plus14 mai 2021
publication
Quality control of protein reagents for the improvement of research data reproducibility.
Lire plus01 mai 2021
publication
Quality control of purified proteins to improve data quality and reproducibility: results from a large-scale survey.
Lire plus01 mai 2021
publication
A High-Affinity Calmodulin-Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells.
Lire plus24 avr. 2021
publication
RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori.
Lire plus01 janv. 2021
publication
PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations.
Lire plus06 nov. 2020
publication
Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
Lire plus15 mai 2019
publication
Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
Lire plus07 mai 2019
publication
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Lire plus01 mai 2019
publication
Regulation of measles virus gene expression by P protein coiled-coil properties.
Lire plus07 févr. 2019
publication
Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity
Lire plus09 janv. 2019
publication
Biochemical characterization of the respiratory syncytial virus N0-P complex in solution
Lire plus09 janv. 2019
publication
Biochemical characterization of the respiratory syncytial virus N-P complex in solution
Lire plus11 sept. 2018
publication
Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9
Lire plus15 janv. 2018
publication
The stress sigma factor of RNA polymerase RpoS/σ is a solvent-exposed open molecule in solution
Lire plus12 janv. 2018
publication
Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.
Lire plus28 sept. 2017
publication
Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem
Lire plus01 août 2017
publication
Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery
Lire plus30 mars 2017
publication
Bacterial kinesin light chain (Bklc) links the Btub cytoskeleton to membranes.
Lire plus29 janv. 2017
publication
The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.
Lire plus31 mai 2016
publication
Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.
Lire plus20 avr. 2016
05 févr. 2016
publication
Neurotoxic phospholipase A2 from rattlesnake as a new ligand and new regulator of prokaryotic receptor GLIC (proton-gated ion channel from G. violaceus)
Lire plus20 janv. 2016
20 nov. 2015
project
Biophysical characterization of the translocation process of Bordetella pertussis adenylate cyclase toxin CyaA
Lire plus18 nov. 2015
17 août 2015
05 mai 2015
29 avr. 2015
publication
Correction: Two Classes of Bacterial IMPDHs according to Their Quaternary Structures and Catalytic Properties
Lire plus23 févr. 2015
publication
Two classes of bacterial IMPDHs according to their quaternary structures and catalytic properties
Lire plus17 févr. 2015
01 janv. 2015
publication
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation.
Lire plus30 déc. 2014
15 oct. 2014
publication
Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/σS subunit of RNA polymerase
Lire plus02 oct. 2014
publication
Community-acquired meticillin-resistant Staphylococcus aureus strain USA300 resists staphylococcal protein A modulation by antibiotics and antimicrobial peptides
Lire plus01 oct. 2014
publication
Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members.
Lire plus30 sept. 2014
publication
Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.
Lire plus06 juin 2014
11 avr. 2014
publication
Interaction of a partially disordered antisigma factor with its partner, the signaling domain of the TonB-dependent transporter HasR
Lire plus15 janv. 2014
publication
Extracellular nucleotide catabolism by the Group B Streptococcus ectonucleotidase NudP increases bacterial survival in blood
Lire plus07 oct. 2013
publication
Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome
Lire plus07 mai 2013
publication
The carboxy-terminal αN helix of the archaeal XerA tyrosine recombinase is a molecular switch to control site-specific recombination
Lire plus02 mai 2013
30 avr. 2013
30 janv. 2013
publication
The α-helical regions of KERP1 are important in Entamoeba histolytica adherence to human cells
Lire plus12 juil. 2012
publication
Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting
Lire plus09 mai 2012
publication
A S-adenosylmethionine methyltransferase-like domain within the essential, Fe-S-containing yeast protein Dre2
Lire plus01 déc. 2011
publication
The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA
Lire plus01 déc. 2011
30 août 2011
publication
Outer membrane targeting of secretin PulD protein relies on disordered domain recognition by a dedicated chaperone
Lire plus25 sept. 2010
publication
Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone
Lire plus20 avr. 2010
publication
Analysis of the Escherichia coli glucosamine-6-phosphate synthase activity by isothermal titration calorimetry and differential scanning calorimetry
Lire plus01 mars 2010
publication
Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA
Lire plus19 janv. 2010
publication
Calmodulin-induced conformational and hydrodynamic changes in the catalytic domain of Bordetella pertussis adenylate cyclase toxin
Lire plus06 janv. 2010
publication
Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2
Lire plus04 janv. 2010
publication
Biochemical and biophysical characterisation of DBL1alpha1-varO, the rosetting domain of PfEMP1 from the VarO line of Plasmodium falciparum
Lire plus13 nov. 2009
publication
Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel
Lire plus24 oct. 2009
publication
Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity
Lire plus23 oct. 2009
publication
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding
Lire plus30 juil. 2009
publication
The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4
Lire plus17 juin 2009
publication
Structure, function, and targets of the transcriptional regulator SvtR from the hyperthermophilic archaeal virus SIRV1
Lire plus17 nov. 2008
publication
RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion
Lire plus29 oct. 2008
publication
The CymR regulator in complex with the enzyme CysK controls cysteine metabolism in Bacillus subtilis
Lire plus03 oct. 2008
01 mai 2008
20 oct. 2006
publication
Marfan syndrome-causing mutations in fibrillin-1 result in gross morphological alterations and highlight the structural importance of the second hybrid domain.
Lire plus01 août 2003
publication
Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus.
Lire plus01 mars 2002
publication