Laboratoire Groupe Junior (G5)

Régulation Spatiale des Génomes

Responsable

Romain Koszul

CNRS UMR3525

Département de Génomes et Génétique

Centre de Bioinformatique, Biostatistique et Biologie Intégrative

• Biophysics
• Cell cycle and division
• Chromatine
• Chromosome
• Evolution
• Genetics
• Genetics, Genomics
• Genomics
• Microbiota
• Nucleus
• Physics, Computer Science, Informatics Systems Biology and Technological Research
• Replication
• Scientific computing
• Archaea
• Bacillus
• Bacillus subtilis
• Bacteria
• Candida
• Candida glabrata
• Escherichia
• Escherichia coli
• Fungi
• Model systems
• Saccharomyces
• Saccharomyces cerevisiae
• Streptomyces
• Streptomyces lividans
• Vibrio
• Vibrio cholerae
• Yeast
• Genetic engineering
• Bionformatics Data Analysis and software
• Molecular Biology/Sequencing/ Gene editing

VOIR TOUSFermer

Présentation

Désolé, cet article est seulement disponible en Anglais Américain.

Membres

Romain Koszul

Responsable de Structure

Responsable

Lyam Baudry

Etudiant(e) en thèse

Martial Marbouty

Post-doctorant(e)

Luciana Lazar Stefanita

Etudiant(e) en thèse

Vittore Scolari

Post-doctorant(e)

Axel Cournac

Ingénieur(e) de Recherche

Héloïse Muller

Post-doctorant(e)

Guillaume Mercy

Etudiant(e) en thèse

Emplois

Post-doctorant(e)

Multiscale analysis of bacterial chromosome organization

The group of Romain Koszul, in the Department of Genomes and Genetics at the Institut Pasteur, is welcoming applications from independent, motivated postdocs to work on various projects related to the fields of chromosome […]

Logiciel

GRAAL: genome assembly from chromosome contact frequencies

A software to reconstruct 1D genome structures from 3D contact data obtained from Hi-C experiments.This movie shows the iterative assembly by GRAAL of the Trichoderma reesei genome (right) using contact frequencies determined by the […]

META3C (MetaHiC)

We have pushed further our analysis about the potential of 3D contact data to solve genomics limitations and problems. We have developed meta3C, a metagenomic chromosome conformation capture approach that allows characterizing individual genomes […]

Financements

• 
• 
• 
• 
• 

Publications

• 2016
  Beyond the bounds of evolution: Synthetic chromosomes… How and what for? - Koszul R - Comptes rendus biologies
• 2016
  A checkpoint control orchestrates the replication of the two chromosomes of Vibrio cholerae. - Val ME, Marbouty M, de Lemos Martins F, Kennedy SP, Kemble H, Bland MJ, Possoz C, Koszul R, Skovgaard O, Mazel D. - Science Advances
• 2016
  Evidence for actin dual role in regulating chromosome organization and dynamics in yeast - Maya Spichal, Alice Brion, Sébastien Herbert, Axel Cournac, Martial Marbouty, Christophe Zimmer, Romain Koszul, Emmanuelle Fabre - Journal of Cell Science
• 2016
  Generation and Analysis of Chromosomal Contact Maps of Yeast Species - Cournac A, Marbouty M, Mozziconacci J, Koszul R - Methods Mol Biol
• 2015
  The 3D folding of metazoan genomes correlates with the association of similar repetitive elements - Cournac A, Koszul R, Mozziconacci J - Nucleic acids research
• 2015
  Metagenome Analysis Exploiting High-Throughput Chromosome Conformation Capture (3C) Data - Marbouty M, Koszul R - Trends in genetics : TIG
• 2015
  Conception et synthèse de néochromosomes - Heloise Muller, Romain Koszul - Médecine thérapeutique / Médecine de la reproduction, gynécologie et endocrinologie
• 2015
  Spatial reorganization of telomeres in long-lived quiescent cells - Guidi M, Ruault M, Marbouty M, Loïodice I, Cournac A, Billaudeau C, Hocher A, Mozziconacci J, Koszul R, Taddei A - Genome biology
• 2015
  Genome-wide replication landscape of Candida glabrata - Descorps-Declère S, Saguez C, Cournac A, Marbouty M, Rolland T, Ma L, Bouchier C, Moszer I, Dujon B, Koszul R, Richard GF - BMC biology
• 2015
  Filling the gap: Micro-C accesses the nucleosomal fiber at 100-1000 bp resolution - Mozziconacci J, Koszul R - Genome biology
• +
  Voir la liste complète de publications

Contact

Phone: +33 1 40 61 33 25
Email: romain.koszul@pasteur.fr

Address
25-28 Rue du Docteur Roux
75015, Paris
France