A software to reconstruct 1D genome structures from 3D contact data obtained from Hi-C experiments.
This movie shows the iterative assembly by GRAAL of the Trichoderma reesei genome (right) using contact frequencies determined by the chromosome conformation capture technique (left). Starting from 77 contigs, GRAAL progressively determines 7 chromosomal scaffolds (the end of the movie is not shown).
The software source code and a readme file are available for download here. The computational method is described in Marie-Nelly et al. Nat Comm 2014.