Laboratoire

Dynamique du Génome

Responsable

Benoit Arcangioli

CNRS UMR3525

Département de Génomes et Génétique

Département de Biologie du développement & cellules souches [Affiliation secondaire]

• Biochemistry
• Cancer biology
• Cell biology and developmental biology
• Cell cycle and division
• Cell genetics
• Cell proliferation, apoptosis and growth
• DNA biosynthesis, modification, repair and degradation
• DNA repair
• Epigenetics and gene regulation
• Evolution
• General biochemistry and metabolism
• Genetics, Genomics
• Genomics
• Health services, health care research
• Microbiology and Infection
• Molecular and Structural Biology and Chemistry
• Molecular interactions
• Mycology
• Non coding RNA
• Protein synthesis, modification and turnover
• Public health research and clinical research
• Recombination
• Replication
• Reproduction
• RNA synthesis, processing, modification and degradation
• Stem cell biology
• Ageing
• Alzheimer
• Amyotrophic lateral sclerosis
• Auditory diseases
• Cancer
• Disorders of Sex Development and fertility
• Genetic disorders
• Huntington
• Multiple sclerosis
• Neurodegenerative diseases
• Neurological diseases
• Other diseases
• Parkinson
• Rare congenital diseases
• Skin cancer
• Fungi
• Model systems
• Schizosaccharomyces
• Schizosaccharomyces pombe
• Yeast
• Anticancer treatments
• Gene therapy, stem cell therapy, regenerative medicine

VOIR TOUSFermer

Présentation

Membres

Benoit Arcangioli

Responsable de Structure

Responsable

Claire Denis

Balveer Singh

Post-doctorant(e)

Célia Raimondi

Etudiant(e) en thèse

Catherine Schurra

Ingénieur(e) de Recherche

Stefania Francesconi

Chercheur(euse) Permanent(e)

Serge Gangloff

Chercheur(euse) Permanent(e)

Samia Miled

Post-doctorant(e)

Projets

Genomic imprinting

Genomic imprinting (Helen V. Crouse, 1960) is necessary for proper growth and development in many species, and as been implicated in cancer, aging and development in humans. The programmed strand-specific imprinting (SSB) at the […]

Publications

• 2014
  Fission yeast Rad52 phosphorylation restrains error prone recombination pathways - Bellini A, Girard PM, Tessier L, Sage E, Francesconi S - PloS one
• 2013
  How to choose the right mate - Arcangioli B - PLoS genetics
• 2013
  Oxidative stress in mammalian cells impinges on the cysteines redox state of human XRCC3 protein and on its cellular localization - Girard PM, Graindorge D, Smirnova V, Rigolet P, Francesconi S, Scanlon S, Sage E - PloS one
• 2013
  Deletion of the fission yeast homologue of human insulinase reveals a TORC1-dependent pathway mediating resistance to proteotoxic stress - Beuzelin C, Evnouchidou I, Rigolet P, Cauvet-Burgevin A, Girard PM, Dardalhon D, Culina S, Gdoura A, van Endert P, Francesconi S - PloS one
• 2013
  Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis - Burkovics P, Sebesta M, Sisakova A, Plault N, Szukacsov V, Robert T, Pinter L, Marini V, Kolesar P, Haracska L, Gangloff S, Krejci L - The EMBO journal
• 2012
  Lsd1 and lsd2 control programmed replication fork pauses and imprinting in fission yeast - Holmes A, Roseaulin L, Schurra C, Waxin H, Lambert S, Zaratiegui M, Martienssen RA, Arcangioli B - Cell reports
• 2012
  Stress activated protein kinase pathway modulates homologous recombination in fission yeast - Bellini A, Girard PM, Lambert S, Tessier L, Sage E, Francesconi S - PloS one
• 2011
  RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II - Zaratiegui M, Castel SE, Irvine DV, Kloc A, Ren J, Li F, de Castro E, Marín L, Chang AY, Goto D, Cande WZ, Antequera F, Arcangioli B, Martienssen RA - Nature
• 2011
  Unravelling UVA-induced mutagenesis - Sage E, Girard PM, Francesconi S - Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
• 2010
  CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR - Zaratiegui M, Vaughn MW, Irvine DV, Goto D, Watt S, Bähler J, Arcangioli B, Martienssen RA - Nature
• +
  Voir la liste complète de publications

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