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Présentation
Membres
Guy-Franck Richard
Chef(fe) de Groupe
Responsable
Anciens Membres
2000
2000
Name
Position
Alix Kerrest
PhD student
Grégoire Michoud
Master student
Valentine Mosbach
PhD student
Cyril saguez
Post-doctoral fellow
Lucie Poggi
PhD student
Olivia Frenoy
Research engineer
Lisa Emmenegger
Research engineer
Wilhelm Vaysse-Zinkhöfer
PhD student
Laureline Bétemps
Research engineer
Saliha Azebi
Research engineer
Voir tout
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Financements
Principales publications
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2021Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations., Nucleic Acids Res 2021 08; 49(14): 8120-8134.
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2021Alternative DNA Structures In Vivo: Molecular Evidence and Remaining Questions., Microbiol Mol Biol Rev 2021 Feb; 85(1): .
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2020Monitoring Double-Strand Break Repair of Trinucleotide Repeats Using a Yeast Fluorescent Reporter Assay., Methods Mol Biol 2020 ; 2056(): 113-120.
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2019Trinucleotide repeat instability during double-strand break repair: from mechanisms to gene therapy., Curr Genet 2019 Feb; 65(1): 17-28.
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2018TALEN-Induced Double-Strand Break Repair of CTG Trinucleotide Repeats., Cell Rep. 2018 Feb 20;22(8):2146-2159.
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2015Shortening trinucleotide repeats using highly specific endonucleases: a possible approach to gene therapy?, Trends Genet. 2015 Apr;31(4):177-86.
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2014Highly specific contractions of a single CAG/CTG trinucleotide repeat by TALEN in yeast, PLoS ONE 2014;9(4):e95611.
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2009SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination, Nat. Struct. Mol. Biol. 2009 Feb;16(2):159-67.
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2008Comparative genomics and molecular dynamics of DNA repeats in eukaryotes, Microbiol. Mol. Biol. Rev. 2008 Dec;72(4):686-727.
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2003Analysis of microsatellites in 13 hemiascomycetous yeast species: mechanisms involved in genome dynamics, J. Mol. Evol. 2003 Jun;56(6):730-41.
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2003Contractions and expansions of CAG/CTG trinucleotide repeats occur during ectopic gene conversion in yeast, by a MUS81-independent mechanism, J. Mol. Biol. 2003 Feb;326(3):769-82.
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2002Transcription and nuclear transport of CAG/CTG trinucleotide repeats in yeast, Nucleic Acids Res. 2002 Aug;30(16):3540-7.
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2001Microsatellite typing as a new tool for identification of Saccharomyces cerevisiae strains, J. Clin. Microbiol. 2001 Feb;39(2):551-9.
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1999Trinucleotide repeats and other microsatellites in yeasts, Res. Microbiol. 1999 Nov-Dec;150(9-10):589-602.
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Contact
Phone: +33-1-45-68-84-36 Email: gfrichar@pasteur.fr Address: 25-28 Rue du Docteur Roux 75015, Paris France