Présentation
Although many clinically and ecologically relevant processes are known to be performed by biofilm communities composed of strict or facultative anaerobic bacteria, biofilms were often studied in aerobic conditions. We use in vitro anaerobic culture systems combined with genetic and genomic approaches to study the molecular basis of biofilm formation by anaerobic commensal and pathogenic bacteria.
Recent articles on this topic
Béchon* N, Mihajlovic* J, Vendrell-Fernandez S, Chain F, Langella P, Beloin C, and Ghigo JM (2020) Capsular polysaccharides cross-regulation modulates Bacteroides thetaiotaomicron biofilm formation. mBio May/June 2020 Vol. 11 Issue 3, e00729-20
Béchon N, Jiménez-Fernández A, Witwinoski J, Bierque E, Taib N, Cokelaer T, Ma L, Ghigo JM, Gribaldo S, Beloin C (2020) Autotransporters drive biofilm formation and auto-aggregation in the diderm Firmicute Veillonella parvula. Journal of Bacteriology, in press.
• Mihajlovic ,J.; Béchon, N.; Ivanova, C.; Chain, F.; Almeida, A.; Langella, P.; Beloin, C. and J.-M. Ghigo. (2019) A putative type V pilus contributes to Bacteroides thetaiotaomicron biofilm formation capacity. Journal of Bacteriology. Mar 4. pii: JB.00650-18. doi: 10.1128/JB.00650-18.
Poppleton, D.I., M. Duchateau, V.R. Hourdel, M. Matondo, J. Flechsler, A. Klingl, C. Beloin*, and S. Gribaldo*. (2017). Outer membrane proteome of Veillonella parvula: A diderm firmicute of the human microbiome. Frontiers in Microbiology, 8, 6979-7017.
Antunes, L.C.S., D. Poppleton, A. Klingl, A. Criscuolo, B. Dupuy, C. Brochier-Armanet, C. Beloin, and S. Gribaldo. (2016). Phylogenomic analysis supports the ancestral presence of LPS-outer membranes in the Firmicutes. eLife. Aug 31;5. e14589. doi: 10.7554.