[embeddoc url=”https://research.pasteur.fr/wp-content/uploads/2015/05/research_pasteur-christophe-beloin-cvdeuxpagestypeanr-dec2022.pdf” download=”all” viewer=”google”] I prepared my PhD in the laboratory of Structure and Expression of Bacterial Genome directed by Dr. Françoise Le Hégarat at the University Paris XI where I studied histone-like proteins of the Gram positive bacteria Bacillus subtilis. I obtained my PhD in 1998. The same year I joined the laboratory of Prof. Charles J. Dorman in Trinity College Dublin as a European Post-doctoral fellow. During these three years my research has been focused on the regulation of virulence gene expression in the pathogenic bacteria Shigella flexneri. In 2001, I came back to France on a postdoctoral proposition in the 5 years group recently created by Dr. Jean-Marc Ghigo. I participated to the implementation of the G5 Genetics of Biofilms Laboratory. In 2003, I was recruited at the Institut Pasteur as Assistant Professor (Chargé de Recherche) and have been promoted Associate Professor in 2014. In the Ghigo’s laboratory, my work focuses on two biofilm-specific phenomena: initial adhesion to surfaces or between bacteria, which is a key step of any colonization process, and biofilms recalcitrance towards antibiotic , a major biofilm behavior responsible for chronic and recurrent infections in clinic. Beyond the importance of a better fundamental understanding of the molecular mechanisms controlling these two biofilm-properties , these studies have also been motivated by my desire to translate, when possible, some aspects of my work into clinically relevant situations involving biofilms. Since 2011 I’m strongly involved in teaching at the Institut Pasteur and I have been appointed Co-director of the Institut Pasteur Microbiology Course in 2014.
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Cours
Microbiology Course Institut Pasteur
I have been appointed in 2010 then Co-director together with Dr Françoise Norel-Bozouklian in 2014 of this Microbiology course. This nine-week theorical and practical course presents the latest advances in molecular and cellular microbiology. […]
2015-09-01 03:00:00
2015-10-30
Europe/Paris
Microbiology Course Institut Pasteur
I have been appointed in 2010 then Co-director together with Dr Françoise Norel-Bozouklian in 2014 of this Microbiology course. This nine-week theorical and practical course presents the latest advances in molecular and cellular microbiology. […]
28 Rue du Docteur Roux, Paris, France
Institut Pasteur Microbiology Course
Françoise Norel has been appointed Co-director of the Institut Pasteur Microbiology Course in 2014. This course is held annually and is part of master trainings proposed by 3 universities: Pierre and Marie Curie (Paris […]
2015-09-01 08:14:07
2015-10-30
Europe/Paris
Institut Pasteur Microbiology Course
Françoise Norel has been appointed Co-director of the Institut Pasteur Microbiology Course in 2014. This course is held annually and is part of master trainings proposed by 3 universities: Pierre and Marie Curie (Paris […]
28 Rue du Docteur Roux, Paris, France
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2024Identification of V. parvula and S. gordonii adhesins mediating co-agregation and its impact on physiology and mixedbiofilm structure., mBio. 2024, in press.
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2024Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance., Nanoscale 2024 Sep 26;16(37): 17567-17584.
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2023Analysis of in-patient evolution of Escherichia coli reveals potential links to relapse of bone and joint infections., J Infect Dis 2023 Dec 2:jiad528.
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2023The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope bridge for phospholipid trafficking., Nat Commun 2023 Nov; 14(1): 7642.
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2023Dual function of OmpM as outer membrane tether and nutrient uptake channel in diderm Firmicutes., Nat Commun 2023 Nov; 14(1): 7152.
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2023Characterization of Pseudomonas aeruginosa l,d-Transpeptidases and Evaluation of Their Role in Peptidoglycan Adaptation to Biofilm Growth., Microbiol Spectr 2023 Aug; 11(4): e0521722.
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2023Escherichia coli SPFH Membrane Microdomain Proteins HflKC Contribute to Aminoglycoside and Oxidative Stress Tolerance., Microbiol Spectr 2023 Aug; 11(4): e0176723.
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2023Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties., Nat Commun 2023 May; 14(1): 2553.
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2023Escherichia coli Aggregates Mediated by Native or Synthetic Adhesins Exhibit Both Core and Adhesin-Specific Transcriptional Responses., Microbiol Spectr 2023 Apr; (): e0069023.
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2023Intermittent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance., Commun Biol 2023 Mar; 6(1): 275.
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