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Biofilms formed by anaerobes
Although many clinically and ecologically relevant processes are known to be performed by biofilm communities composed of strict or facultative anaerobic bacteria, biofilms were often studied in aerobic conditions. We use in vitro anaerobic culture systems […]
Molecular Bases of Colonization Resistance
We use in vitro and in vivo models of polymicrobial communities in order to better understand the molecular events underlying colonization resistance and pathogen exclusion by commensal bacteria Articles on this topic David Pérez-Pascual, Sol Vendrell-Fernandez, […]
Although competitive interactions between bacteria (bacterial interference), are likely to represent a key aspect of many infectious processes, the nature of these interactions within mixed biofilm communities is poorly understood. We use in vitro biofilm models […]
Biofilm Volatile Compounds
Bacteria produce and release into their headspace a wide variety of volatile secondary metabolites. However, While detection and quantification of these volatiles as attractive or repellent odors and aromas are of great interest in food and cosmetic […]
Biofilm formation on medical devices is associated with hospital-acquired (nosocomial) infections. Due to biofilms’ high tolerance to antibiotics, classical treatments lack efficacy, and removal of the biofilm-contaminated device is often the only therapeutic option. […]
We designed a continuous-flow culture system in which biofilm formation can be reproducibly monitored and controlled in microfermentors handled at flow-rates avoiding accumulation of planktonic bacteria. This model is suited for biofilm macroscopic analysis, […]
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