LabEx IBEID – Integrative Biology of Emerging Infectious Diseases
Presentation Le but du projet Biologie Intégrative des Maladies Infectieuses Emergentes (IBEID), coordonné par les professeurs Philippe Sansonetti et Pascale Cossart, est de développer une structure pour anticiper et lutter contre les maladies […]
Evolutionary history of the classical biotype of Vibrio cholerae O1
The classical biotype of Vibrio cholerae O1 was responsible for the first six cholera pandemics, but is relatively unknown, with only 20 genome sequences (50% of which come from the same geographic area) for […]
Genomic insights into the 2016-2017 cholera epidemic in Yemen
Cholera is thought by many to be a disease of the Victorian era. However, Yemen has recently experienced one of the largest ever cholera epidemics. The first cases were declared in September 2016, and […]
Historical antibiotic-resistant populations of S. enterica serotype Typhimurium
Little is known about the emergence and spread of the first antibiotic-resistant populations. It is believed, for example, that the very common penicillinase gene, blaTEM-1, discovered for the first time in E. coli in Greece […]
Phylodynamics of Vibrio cholerae O1 in Africa (1970-2014)
In 1970, ten years after the beginning of the 7th pandemic (Indonesia, 1961), cholera hit Africa, where it has remained entrenched. Three decades later, the reported incidence of indigenous cholera in sub-Saharan Africa was […]
Private: Histoire évolutive du bacille de la dysenterie épidémique (Shigella dysenteriae de type 1)
L’agent de la dysenterie épidémique, la bactérie Shigella dysenteriae de type 1, a été isolé au Japon en 1897 par le Dr Kyoshi Shiga au cours d’une vaste épidémie de diarrhée sanglante ayant provoqué […]
Phylogenomics of Shiga’s epidemic dysentery bacillus (Shigella dysenteriae type 1)
The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]
The Unit includes two National Reference Centers (CNR) and a WHO Collaborating Center. Our interests are the population dynamics of bacterial enteric pathogens such Salmonella, Shigella/Escherichia coli and Vibrio, with a special focus on […]
Salmonella CRISPR Typing
CRISPR polymorphism is a powerful tool to subtype Salmonella strains and is now used in routine for epidemiological investigations. This tool gets a CRISPR profile by identifying the presence of known spacers and direct […]
2019Genomic insights into the 2016-2017 cholera epidemic in Yemen, Nature 2019 Jan;.
2018Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens, Science 2018 05;360(6390):733-738.
2018Horizontal antimicrobial resistance transfer drives epidemics of multiple Shigella species, Nat Commun 2018 Apr;9(1):1462.
2017Early transmissible ampicillin resistance in zoonotic Salmonella enterica serotype Typhimurium in the late 1950s: a retrospective, whole-genome sequencing study, Lancet Infect Dis 2018 Feb;18(2):207-214.
2017Integrated view of Vibrio cholerae in the Americas, Science 2017 11;358(6364):789-793.
2017Genomic history of the seventh pandemic of cholera in Africa, Science 2017 11;358(6364):785-789.
2017The clinical and microbiological characteristics of enteric fever in Cambodia, 2008-2015, PLoS Negl Trop Dis 2017 Sep;11(9):e0005964.
2017Private: Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings, Nat. Genet. 2017 Mar;49(4):651.
2017Private: Multinational outbreak of travel-related Salmonella Chester infections in Europe, summers 2014 and 2015, Euro Surveill. 2017 Feb;22(7).
2016Genome-scale rates of evolutionary change in bacteria, Microb Genom 2016 Nov;2(11):e000094.
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