LabEx IBEID – Integrative Biology of Emerging Infectious Diseases
Presentation Le but du projet Biologie Intégrative des Maladies Infectieuses Emergentes (IBEID), coordonné par les professeurs Philippe Sansonetti et Pascale Cossart, est de développer une structure pour anticiper et lutter contre les maladies […]
Evolutionary history of the classical biotype of Vibrio cholerae O1
The classical biotype of Vibrio cholerae O1 was responsible for the first six cholera pandemics, but is relatively unknown, with only 20 genome sequences (50% of which come from the same geographic area) for […]
Genomic insights into the 2016-2017 cholera epidemic in Yemen
Cholera is thought by many to be a disease of the Victorian era. However, Yemen has recently experienced one of the largest ever cholera epidemics. The first cases were declared in September 2016, and […]
Historical antibiotic-resistant populations of S. enterica serotype Typhimurium
Little is known about the emergence and spread of the first antibiotic-resistant populations. It is believed, for example, that the very common penicillinase gene, blaTEM-1, discovered for the first time in E. coli in Greece […]
Phylodynamics of Vibrio cholerae O1 in Africa (1970-2014)
In 1970, ten years after the beginning of the 7th pandemic (Indonesia, 1961), cholera hit Africa, where it has remained entrenched. Three decades later, the reported incidence of indigenous cholera in sub-Saharan Africa was […]
Phylogenomics of Shiga’s epidemic dysentery bacillus (Shigella dysenteriae type 1)
The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]
The Unit includes two National Reference Centers (CNR) and a WHO Collaborating Center. Our interests are the population dynamics of bacterial enteric pathogens such Salmonella, Shigella/Escherichia coli and Vibrio, with a special focus on […]
2019Genomic insights into the 2016-2017 cholera epidemic in Yemen, Nature 2019 Jan;.
2018Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens, Science 2018 05;360(6390):733-738.
2018Horizontal antimicrobial resistance transfer drives epidemics of multiple Shigella species, Nat Commun 2018 Apr;9(1):1462.
2017Early transmissible ampicillin resistance in zoonotic Salmonella enterica serotype Typhimurium in the late 1950s: a retrospective, whole-genome sequencing study, Lancet Infect Dis 2018 Feb;18(2):207-214.
2017Integrated view of Vibrio cholerae in the Americas, Science 2017 11;358(6364):789-793.
2017Genomic history of the seventh pandemic of cholera in Africa, Science 2017 11;358(6364):785-789.
2017The clinical and microbiological characteristics of enteric fever in Cambodia, 2008-2015, PLoS Negl Trop Dis 2017 Sep;11(9):e0005964.
2016Genome-scale rates of evolutionary change in bacteria, Microb Genom 2016 Nov;2(11):e000094.
2016Genomic analysis of Salmonella enterica serotype Paratyphi A during an outbreak in Cambodia, 2013-2015, Microb Genom 2016 Nov;2(11):e000092.
2016An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid, Nat Commun 2016 Oct;7:12827.
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