Timeline

Zacarias Garcia
Research Engineer
14 Jun 2021
publication

Quorum sensing governs collective dendritic cell activation in vivo.

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15 Apr 2021
publication

Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti-tumor activity in vivo.

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26 Mar 2021
publication

A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity.

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19 Feb 2021
news

Improving immunotherapies for blood cancers: real-time exploration in the tumor

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01 Feb 2021
publication

Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis.

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09 Mar 2020
publication

Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment

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01 Mar 2020
publication

Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment.

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01 Aug 2018
publication

A human immune system mouse model with robust lymph node development.

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27 Mar 2018
publication

Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division

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04 Oct 2016
publication

Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies.

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12 Jan 2016
publication

The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation

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21 Dec 2015
publication

In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity

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14 Sep 2015
publication

Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest

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15 Jun 2015
project

Immune responses against tumors

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11 May 2015
team

Dynamics of Immune Responses

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01 Nov 2013
publication

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging

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01 Feb 2013
publication

Synergy of the antibiotic colistin with echinocandin antifungals in Candida species

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15 Nov 2012
publication

Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis

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12 Oct 2012
publication

Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles

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13 Aug 2012
publication

Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis

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10 Jul 2012
publication

The CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactions

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25 Jul 2011
publication

Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells

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14 Jan 2011
publication

Selective expansion of merocytic dendritic cells and CD8DCs confers anti-tumour effect of Fms-like tyrosine kinase 3-ligand treatment in vivo

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24 Sep 2010
publication

Visualizing the functional diversification of CD8+ T cell responses in lymph nodes

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18 Aug 2010
publication

Prolonged antigen storage endows merocytic dendritic cells with enhanced capacity to prime anti-tumor responses in tumor-bearing mice

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01 Jun 2009
publication

Dendritic cells use endocytic pathway for cross-priming class Ib MHC-restricted CD8alphaalpha+TCRalphabeta+ T cells with regulatory properties

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01 Apr 2008
publication

Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway

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15 Jul 2007
publication

Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes

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02 Mar 2007
publication

Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion

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01 Aug 2006
publication

Cutting edge: cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells

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11 Apr 2006
publication

Relationship between DNA methylation and histone acetylation levels, cell redox and cell differentiation states in sugarbeet lines

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07 Nov 2005
publication

CD4 T cells integrate signals delivered during successive DC encounters in vivo

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14 Feb 2005
publication

Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo

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01 Mar 2003
publication

Role of T cell help and endoplasmic reticulum targeting in protective CTL response against influenza virus

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13 Feb 2001
publication

Human T cell leukemia virus Type I (HTLV-I) infection induces greater expansions of CD8 T lymphocytes in persons with HTLV-I-associated myelopathy/tropical spastic paraparesis than in asymptomatic carriers

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01 Oct 1999
publication

H-2 class I knockout, HLA-A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies

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01 Jul 1999
publication

Molecular characterization of cDNAs encoding squirrel monkey (Saïmiri sciureus) CD8 alpha and beta chains

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15 May 1998
publication

Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia

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01 Jul 1995
publication

Restriction of self-antigen presentation to cytolytic T lymphocytes by mouse peptide pumps

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01 May 1993
publication

Abrogation of H-2-restricted CTL responses and efficient recognition of HLA-A3 molecules in DBA/2 HLA/A24 responder mice

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