Timeline
Zacarias Garcia
Research Engineer
01 Apr 2024
publication
Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes.
Read more25 Mar 2024
news
New publication – Anti-PD-1 therapy triggers Tfh cell–dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes
Read more05 Jun 2023
news
New publication – Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity
Read more29 May 2023
publication
Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity.
Read more17 Feb 2023
publication
Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics.
Read more29 Aug 2022
23 Aug 2022
19 Jul 2022
publication
Spatiotemporal dynamics of calcium signals during neutrophil cluster formation.
Read more14 Jun 2021
15 Apr 2021
publication
Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti-tumor activity in vivo.
Read more26 Mar 2021
publication
A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity.
Read more19 Feb 2021
01 Feb 2021
publication
Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis.
Read more09 Mar 2020
publication
Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment
Read more01 Mar 2020
publication
Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment.
Read more23 Nov 2018
01 Aug 2018
27 Mar 2018
publication
Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division
Read more04 Oct 2016
publication
Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies.
Read more12 Jan 2016
publication
The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation
Read more21 Dec 2015
publication
In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity
Read more14 Sep 2015
publication
Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest
Read more15 Jun 2015
11 May 2015
01 Nov 2013
publication
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
Read more01 Feb 2013
publication
Synergy of the antibiotic colistin with echinocandin antifungals in Candida species
Read more15 Nov 2012
publication
Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis
Read more12 Oct 2012
publication
Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles
Read more13 Aug 2012
publication
Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis
Read more10 Jul 2012
publication
The CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactions
Read more25 Jul 2011
publication
Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells
Read more14 Jan 2011
publication
Selective expansion of merocytic dendritic cells and CD8DCs confers anti-tumour effect of Fms-like tyrosine kinase 3-ligand treatment in vivo
Read more24 Sep 2010
publication
Visualizing the functional diversification of CD8+ T cell responses in lymph nodes
Read more18 Aug 2010
publication
Prolonged antigen storage endows merocytic dendritic cells with enhanced capacity to prime anti-tumor responses in tumor-bearing mice
Read more01 Jun 2009
publication
Dendritic cells use endocytic pathway for cross-priming class Ib MHC-restricted CD8alphaalpha+TCRalphabeta+ T cells with regulatory properties
Read more01 Apr 2008
publication
Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway
Read more15 Jul 2007
publication
Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes
Read more02 Mar 2007
publication
Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion
Read more01 Aug 2006
publication
Cutting edge: cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells
Read more11 Apr 2006
publication
Relationship between DNA methylation and histone acetylation levels, cell redox and cell differentiation states in sugarbeet lines
Read more07 Nov 2005
publication
CD4 T cells integrate signals delivered during successive DC encounters in vivo
Read more14 Feb 2005
publication
Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo
Read more01 Mar 2003
publication
Role of T cell help and endoplasmic reticulum targeting in protective CTL response against influenza virus
Read more13 Feb 2001
publication
Human T cell leukemia virus Type I (HTLV-I) infection induces greater expansions of CD8 T lymphocytes in persons with HTLV-I-associated myelopathy/tropical spastic paraparesis than in asymptomatic carriers
Read more01 Oct 1999
publication
H-2 class I knockout, HLA-A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies
Read more01 Jul 1999
publication
Molecular characterization of cDNAs encoding squirrel monkey (Saïmiri sciureus) CD8 alpha and beta chains
Read more15 May 1998
publication
Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia
Read more01 Jul 1995
publication
Restriction of self-antigen presentation to cytolytic T lymphocytes by mouse peptide pumps
Read more01 May 1993
publication