Ligne de temps
Zacarias Garcia
Ingénieur(e) de Recherche
01 avr. 2024
publication
Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes.
Lire plus25 mars 2024
news
New publication – Anti-PD-1 therapy triggers Tfh cell–dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes
Lire plus05 juin 2023
news
New publication – Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity
Lire plus29 mai 2023
publication
Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity.
Lire plus17 févr. 2023
publication
Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics.
Lire plus29 août 2022
23 août 2022
19 juil. 2022
publication
Spatiotemporal dynamics of calcium signals during neutrophil cluster formation.
Lire plus14 juin 2021
15 avr. 2021
publication
Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti-tumor activity in vivo.
Lire plus26 mars 2021
publication
A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity.
Lire plus19 févr. 2021
01 févr. 2021
publication
Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis.
Lire plus09 mars 2020
publication
Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment
Lire plus01 mars 2020
publication
Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment.
Lire plus23 nov. 2018
01 août 2018
27 mars 2018
publication
Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division
Lire plus04 oct. 2016
publication
Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies.
Lire plus12 janv. 2016
publication
The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation
Lire plus21 déc. 2015
publication
In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity
Lire plus14 sept. 2015
publication
Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest
Lire plus15 juin 2015
11 mai 2015
01 nov. 2013
publication
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
Lire plus01 févr. 2013
publication
Synergy of the antibiotic colistin with echinocandin antifungals in Candida species
Lire plus15 nov. 2012
publication
Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis
Lire plus12 oct. 2012
publication
Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles
Lire plus13 août 2012
publication
Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis
Lire plus10 juil. 2012
publication
The CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactions
Lire plus25 juil. 2011
publication
Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells
Lire plus14 janv. 2011
publication
Selective expansion of merocytic dendritic cells and CD8DCs confers anti-tumour effect of Fms-like tyrosine kinase 3-ligand treatment in vivo
Lire plus24 sept. 2010
publication
Visualizing the functional diversification of CD8+ T cell responses in lymph nodes
Lire plus18 août 2010
publication
Prolonged antigen storage endows merocytic dendritic cells with enhanced capacity to prime anti-tumor responses in tumor-bearing mice
Lire plus01 juin 2009
publication
Dendritic cells use endocytic pathway for cross-priming class Ib MHC-restricted CD8alphaalpha+TCRalphabeta+ T cells with regulatory properties
Lire plus01 avr. 2008
publication
Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway
Lire plus15 juil. 2007
publication
Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes
Lire plus02 mars 2007
publication
Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion
Lire plus01 août 2006
publication
Cutting edge: cognate CD4 help promotes recruitment of antigen-specific CD8 T cells around dendritic cells
Lire plus11 avr. 2006
publication
Relationship between DNA methylation and histone acetylation levels, cell redox and cell differentiation states in sugarbeet lines
Lire plus07 nov. 2005
publication
CD4 T cells integrate signals delivered during successive DC encounters in vivo
Lire plus14 févr. 2005
publication
Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo
Lire plus01 mars 2003
publication
Role of T cell help and endoplasmic reticulum targeting in protective CTL response against influenza virus
Lire plus13 févr. 2001
publication
Human T cell leukemia virus Type I (HTLV-I) infection induces greater expansions of CD8 T lymphocytes in persons with HTLV-I-associated myelopathy/tropical spastic paraparesis than in asymptomatic carriers
Lire plus01 oct. 1999
publication
H-2 class I knockout, HLA-A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies
Lire plus01 juil. 1999
publication
Molecular characterization of cDNAs encoding squirrel monkey (Saïmiri sciureus) CD8 alpha and beta chains
Lire plus15 mai 1998
publication
Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia
Lire plus01 juil. 1995
publication
Restriction of self-antigen presentation to cytolytic T lymphocytes by mouse peptide pumps
Lire plus01 mai 1993
publication