Timeline

Laurence Weiss

page

01 Jan 2016

publication

Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles.

02 Nov 2015

publication

Rosuvastatin is effective to decrease CD8 T-cell activation only in HIV-infected patients with high residual T-cell activation under antiretroviral therapy

24 Sep 2015

publication

A low HIV-DNA level in peripheral blood mononuclear cells at antiretroviral treatment interruption predicts a higher probability of maintaining viral control

20 Sep 2015

project

Regulation of retroviral infections

06 Aug 2015

publication

Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical Isolates

04 Jul 2015

project

Innate Immunity and HIV infection

07 Jun 2015

publication

Dual treatment with lopinavir-ritonavir plus lamivudine versus triple treatment with lopinavir-ritonavir plus lamivudine or emtricitabine and a second nucleos(t)ide reverse transcriptase inhibitor for maintenance of HIV-1 viral suppression (OLE): a randomised, open-label, non-inferiority trial

28 May 2015

publication

Real-life long-term omalizumab therapy in children with severe allergic asthma

17 May 2015

publication

Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR

10 Apr 2015

publication

Does transient cART started during primary HIV infection undermine the long-term immunologic and virologic response on cART resumption?

01 Apr 2015

publication

Why START? Reflections that led to the conduct of this large long-term strategic HIV trial

12 Jan 2015

publication

Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells

19 Nov 2014

publication

Clinical features and risk factors for atazanavir (ATV)-associated urolithiasis: a case-control study

02 Nov 2014

publication

CD4+ cell count recovery in naïve patients initiating cART, who achieved and maintained plasma HIV-RNA suppression

03 Oct 2014

publication

Phenotype alterations in regulatory T-cell subsets in primary HIV infection and identification of Tr1-like cells as the main interleukin 10-producing CD4+ T cells

05 Aug 2014

publication

Central venous thrombosis and thrombophilia in cystic fibrosis: A prospective study

04 Aug 2014

publication

Ritonavir-boosted darunavir combined with raltegravir or tenofovir-emtricitabine in antiretroviral-naive adults infected with HIV-1: 96 week results from the NEAT001/ANRS143 randomised non-inferiority trial

17 Jul 2014

publication

T-cell activation positively correlates with cell-associated HIV-DNA level in viremic patients with primary or chronic HIV-1 infection

18 Apr 2014

publication

Autoimmune diseases in HIV-infected patients: 52 cases and literature review

18 Sep 2013

publication

Associations between 25-hydroxyvitamin D and immunologic, metabolic, inflammatory markers in treatment-naive HIV-infected persons: the ANRS CO9 «COPANA» cohort study

08 Aug 2013

publication

Imported amoebic liver abscess in France

08 Aug 2013

publication

Immunity and squamous cell carcinoma of the anus: epidemiological, clinical and therapeutic aspects

01 Aug 2013

publication

Is clinical practice concordant with the changes in guidelines for antiretroviral therapy initiation during primary and chronic HIV-1 infection? The ANRS PRIMO and COPANA cohorts

09 Jul 2013

publication

Sexually-transmitted/founder HIV-1 cannot be directly predicted from plasma or PBMC-derived viral quasispecies in the transmitting partner

20 Jun 2013

publication

The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation

21 Mar 2013

publication

Add-on omalizumab in children with severe allergic asthma: a 1-year real life survey

11 Mar 2013

publication

Efficacy, safety, and pharmacokinetics of once-daily boosted darunavir in pretreated HIV-infected patients

28 Jan 2013

publication

Lack of regression of anal squamous intraepithelial lesions despite immune restoration under cART

31 Oct 2012

publication

[Anal intraepithelial neoplasia]

04 Oct 2012

publication

The split personality of regulatory T cells in HIV infection

27 Mar 2012

publication

Effect of intermittent interleukin-2 therapy on CD4+ T-cell counts following antiretroviral cessation in patients with HIV

14 Jan 2012

publication

Level of double negative T cells, which produce TGF-β and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection.

14 Jan 2012

publication

Burden of HIV disease and comorbidities on the chances of maintaining employment in the era of sustained combined antiretoviral therapies use

01 Jan 2012

publication

Immune deficiency could be an early risk factor for altered insulin sensitivity in antiretroviral-naive HIV-1-infected patients: the ANRS COPANA cohort

28 Dec 2011

publication

Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study

19 Dec 2011

publication

Human CD90 identifies Th17/Tc17 T cell subsets that are depleted in HIV-infected patients

22 Nov 2011

publication

Repeat kidney biopsies fail to detect differences between azathioprine and mycophenolate mofetil maintenance therapy for lupus nephritis: data from the MAINTAIN Nephritis Trial

30 Aug 2011

publication

Polyacrylamide hydrogel injection in the management of human immunodeficiency virus-related facial lipoatrophy: results of the LIPOPHILL open-label study

21 Apr 2011

publication

CD4 dynamics over a 15 year-period among HIV controllers enrolled in the ANRS French observatory

22 Feb 2011

publication

Dynamics of enfuvirtide resistance mutations in enfuvirtide-experienced patients remaining in virological failure under salvage therapy

01 Nov 2010

publication

A high HIV DNA level in PBMCs at antiretroviral treatment interruption predicts a shorter time to treatment resumption, independently of the CD4 nadir

13 Oct 2010

publication

Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy

07 Oct 2010

publication

Alternative splicing at a NAGNAG acceptor site as a novel phenotype modifier

10 Sep 2010

publication

Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial

31 Aug 2010

publication

Predictors of bacterial pneumonia in Evaluation of Subcutaneous Interleukin-2 in a Randomized International Trial (ESPRIT)

16 Aug 2010

publication

[French guidelines for sweat test practice and interpretation for cystic fibrosis neonatal screening]

14 Aug 2010

publication

Optimization and robustness of blood tests for liver fibrosis and cirrhosis

11 Aug 2010

publication

IL-2 therapy: potential impact of the CD4 cell count at initiation on clinical efficacy–results from the ANRS CO4 cohort

21 Jul 2010

publication

Relationship between regulatory T cells and immune activation in human immunodeficiency virus-infected patients interrupting antiretroviral therapy

24 May 2010

publication

In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients

18 Apr 2010

publication

Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection

27 Mar 2010

publication

High frequency of integrase Q148R minority variants in HIV-infected patients naive of integrase inhibitors

03 Dec 2009

publication

Foscarnet as salvage therapy in HIV-2-infected patient with antiretroviral treatment failure

01 Nov 2009

publication

Trends in post-infection CD4 cell counts and plasma HIV-1 RNA levels in HIV-1-infected patients in France between 1997 and 2005

15 Oct 2009

publication

Switch from enfuvirtide to raltegravir in virologically suppressed multidrug-resistant HIV-1-infected patients: a randomized open-label trial

24 Sep 2009

publication

Design of a HIV-1-derived HLA-B07.02-restricted polyepitope construct

10 Aug 2009

publication

Longitudinal analysis of raltegravir susceptibility and integrase replication capacity of human immunodeficiency virus type 1 during virologic failure

17 Jul 2009

publication

Immunological success is predicted by enfuvirtide but not interleukin-2 therapy in immunodepressed patients

01 Jun 2009

publication

Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV

16 Mar 2009

publication

Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment

01 Feb 2009

publication

Interleukine-2 therapy does not increase the risk of Hodgkin or non-Hodgkin lymphoma in HIV-infected patients: results from FHDH ANRS CO4

28 Jan 2009

publication

Multidrug-experienced HIV-1-infected women demonstrated similar virological and immunological responses to tipranavir/ritonavir compared with men

01 Jan 2009

publication

A population analysis of weight-related differences in lopinavir pharmacokinetics and possible consequences for protease inhibitor-naive and -experienced patients

30 Nov 2008

publication

HIV-specific regulatory T cells are associated with higher CD4 cell counts in primary infection

28 Aug 2008

publication

Foscarnet salvage therapy efficacy is associated with the presence of thymidine-associated mutations (TAMs) in HIV-infected patients

04 Apr 2008

publication

Clinically validated mutation scores for HIV-1 resistance to fosamprenavir/ritonavir

05 Mar 2008

publication

Quantification of seven nucleoside/nucleotide reverse transcriptase inhibitors in human plasma by high-performance liquid chromatography with tandem mass-spectrometry

12 Sep 2007

publication

Long-term effects of intermittent interleukin-2 therapy in chronic HIV-infected patients (ANRS 048-079 Trials)

01 Mar 2007

publication

Predictors of CD4 count change over 8 months of follow up in HIV-1-infected patients with a CD4 count>or=300 cells/microL who were assigned to 7.5 MIU interleukin-2

01 Jan 2007

publication

Increased polymorphism in the HR-1 gp41 env gene encoding the enfuvirtide (T-20) target in HIV-1 variants harboring multiple antiretroviral drug resistance mutations in the pol gene

30 Jun 2006

publication

Alteration of cytochrome oxidase subunit I labeling is associated with severe mitochondriopathy in NRTI-related hepatotoxicity in HIV patients

01 Jan 2006

publication

Sexually transmitted acute infection with a clustered genotype 4 hepatitis C virus in HIV-1-infected men and inefficacy of early antiviral therapy

11 Nov 2005

publication

HIV infection in older patients in the HAART era

01 Aug 2005

publication

Recurring acute abdominal pains in an adolescent as the presenting manifestations of hereditary angioneurotic oedema

01 Jul 2005

publication

Response to highly active antiretroviral therapy at 6 months and long-term disease progression in HIV-1 infection

08 Dec 2004

publication

Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome

22 Jul 2004

publication

Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

01 Jul 2004

publication

Sustained exacerbation of cryoglobulinaemia-related vasculitis following treatment of hepatitis C with peginterferon alfa

15 Jun 2004

publication

Defective dendritic cell function in HIV-infected patients receiving effective highly active antiretroviral therapy: neutralization of IL-10 production and depletion of CD4+CD25+ T cells restore high levels of HIV-specific CD4+ T cell responses induced by dendritic cells generated in the presence of IFN-alpha

07 Jun 2004

publication

Dendritic cells generated in the presence of interferon-alpha stimulate allogeneic CD4+ T-cell proliferation: modulation by autocrine IL-10, enhanced T-cell apoptosis and T regulatory type 1 cells

12 Apr 2004

publication

Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames

01 Mar 2004

publication

Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases

01 Jan 2004

publication

Unusual pulmonary Enterocytozoon bieneusi microsporidiosis in an AIDS patient: case report and review

17 Oct 2003

publication

Successful implementation of a low-cost method for enumerating CD4+ T lymphocytes in resource-limited settings: the ANRS 12-26 study

15 Aug 2003

publication

Dendritic cells generated in the presence of granulocyte-macrophage colony-stimulating factor and IFN-alpha are potent inducers of HIV-specific CD8 T cells

01 Jul 2003

publication

Intraperitoneal pressure in children: fill-volume related and impacted by body mass index

01 Apr 2003

publication

Toxic effects of nucleoside reverse transcriptase inhibitors on the liver. Value of electron microscopy analysis for the diagnosis of mitochondrial cytopathy

14 Feb 2003

publication

Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: a randomized controlled trial

01 Jan 2003

publication

One-Year Evaluation of the Safety and Efficacy of Ipratropium Bromide HFA and CFC Inhalation Aerosols in Patients with Chronic Obstructive Pulmonary Disease

29 Oct 2002

publication

First model of spontaneous vagal hyperreactivity and its mode of genetic transmission

15 Aug 2002

publication

Prevalence of monoclonal gammopathy in patients presenting with acquired angioedema type 2

01 Jun 2002

publication

[Immune-based therapies and HIV infection]

01 Jan 2002

publication

A little guide for advanced search:

Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles.

Rosuvastatin is effective to decrease CD8 T-cell activation only in HIV-infected patients with high residual T-cell activation under antiretroviral therapy

A low HIV-DNA level in peripheral blood mononuclear cells at antiretroviral treatment interruption predicts a higher probability of maintaining viral control

Regulation of retroviral infections

Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical Isolates

Innate Immunity and HIV infection

Dual treatment with lopinavir-ritonavir plus lamivudine versus triple treatment with lopinavir-ritonavir plus lamivudine or emtricitabine and a second nucleos(t)ide reverse transcriptase inhibitor for maintenance of HIV-1 viral suppression (OLE): a randomised, open-label, non-inferiority trial

Real-life long-term omalizumab therapy in children with severe allergic asthma

Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR

Does transient cART started during primary HIV infection undermine the long-term immunologic and virologic response on cART resumption?

Why START? Reflections that led to the conduct of this large long-term strategic HIV trial

Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells

Clinical features and risk factors for atazanavir (ATV)-associated urolithiasis: a case-control study

CD4+ cell count recovery in naïve patients initiating cART, who achieved and maintained plasma HIV-RNA suppression

Phenotype alterations in regulatory T-cell subsets in primary HIV infection and identification of Tr1-like cells as the main interleukin 10-producing CD4+ T cells

Central venous thrombosis and thrombophilia in cystic fibrosis: A prospective study

Ritonavir-boosted darunavir combined with raltegravir or tenofovir-emtricitabine in antiretroviral-naive adults infected with HIV-1: 96 week results from the NEAT001/ANRS143 randomised non-inferiority trial

T-cell activation positively correlates with cell-associated HIV-DNA level in viremic patients with primary or chronic HIV-1 infection

Autoimmune diseases in HIV-infected patients: 52 cases and literature review

Associations between 25-hydroxyvitamin D and immunologic, metabolic, inflammatory markers in treatment-naive HIV-infected persons: the ANRS CO9 «COPANA» cohort study

Imported amoebic liver abscess in France

Immunity and squamous cell carcinoma of the anus: epidemiological, clinical and therapeutic aspects

Is clinical practice concordant with the changes in guidelines for antiretroviral therapy initiation during primary and chronic HIV-1 infection? The ANRS PRIMO and COPANA cohorts

Sexually-transmitted/founder HIV-1 cannot be directly predicted from plasma or PBMC-derived viral quasispecies in the transmitting partner

The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation

Add-on omalizumab in children with severe allergic asthma: a 1-year real life survey

Efficacy, safety, and pharmacokinetics of once-daily boosted darunavir in pretreated HIV-infected patients

Lack of regression of anal squamous intraepithelial lesions despite immune restoration under cART

[Anal intraepithelial neoplasia]

The split personality of regulatory T cells in HIV infection

Effect of intermittent interleukin-2 therapy on CD4+ T-cell counts following antiretroviral cessation in patients with HIV

Level of double negative T cells, which produce TGF-β and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection.

Burden of HIV disease and comorbidities on the chances of maintaining employment in the era of sustained combined antiretoviral therapies use

Immune deficiency could be an early risk factor for altered insulin sensitivity in antiretroviral-naive HIV-1-infected patients: the ANRS COPANA cohort

Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study

Human CD90 identifies Th17/Tc17 T cell subsets that are depleted in HIV-infected patients

Repeat kidney biopsies fail to detect differences between azathioprine and mycophenolate mofetil maintenance therapy for lupus nephritis: data from the MAINTAIN Nephritis Trial

Polyacrylamide hydrogel injection in the management of human immunodeficiency virus-related facial lipoatrophy: results of the LIPOPHILL open-label study

CD4 dynamics over a 15 year-period among HIV controllers enrolled in the ANRS French observatory

Dynamics of enfuvirtide resistance mutations in enfuvirtide-experienced patients remaining in virological failure under salvage therapy

A high HIV DNA level in PBMCs at antiretroviral treatment interruption predicts a shorter time to treatment resumption, independently of the CD4 nadir

Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy

Alternative splicing at a NAGNAG acceptor site as a novel phenotype modifier

Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial

Predictors of bacterial pneumonia in Evaluation of Subcutaneous Interleukin-2 in a Randomized International Trial (ESPRIT)

[French guidelines for sweat test practice and interpretation for cystic fibrosis neonatal screening]

Optimization and robustness of blood tests for liver fibrosis and cirrhosis

IL-2 therapy: potential impact of the CD4 cell count at initiation on clinical efficacy–results from the ANRS CO4 cohort

Relationship between regulatory T cells and immune activation in human immunodeficiency virus-infected patients interrupting antiretroviral therapy

In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients

Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection

High frequency of integrase Q148R minority variants in HIV-infected patients naive of integrase inhibitors

Foscarnet as salvage therapy in HIV-2-infected patient with antiretroviral treatment failure

Trends in post-infection CD4 cell counts and plasma HIV-1 RNA levels in HIV-1-infected patients in France between 1997 and 2005

Switch from enfuvirtide to raltegravir in virologically suppressed multidrug-resistant HIV-1-infected patients: a randomized open-label trial

Design of a HIV-1-derived HLA-B07.02-restricted polyepitope construct

Longitudinal analysis of raltegravir susceptibility and integrase replication capacity of human immunodeficiency virus type 1 during virologic failure

Immunological success is predicted by enfuvirtide but not interleukin-2 therapy in immunodepressed patients

Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV

Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment

Interleukine-2 therapy does not increase the risk of Hodgkin or non-Hodgkin lymphoma in HIV-infected patients: results from FHDH ANRS CO4

Multidrug-experienced HIV-1-infected women demonstrated similar virological and immunological responses to tipranavir/ritonavir compared with men

A population analysis of weight-related differences in lopinavir pharmacokinetics and possible consequences for protease inhibitor-naive and -experienced patients

HIV-specific regulatory T cells are associated with higher CD4 cell counts in primary infection

Foscarnet salvage therapy efficacy is associated with the presence of thymidine-associated mutations (TAMs) in HIV-infected patients

Clinically validated mutation scores for HIV-1 resistance to fosamprenavir/ritonavir

Quantification of seven nucleoside/nucleotide reverse transcriptase inhibitors in human plasma by high-performance liquid chromatography with tandem mass-spectrometry

Long-term effects of intermittent interleukin-2 therapy in chronic HIV-infected patients (ANRS 048-079 Trials)

Predictors of CD4 count change over 8 months of follow up in HIV-1-infected patients with a CD4 count>or=300 cells/microL who were assigned to 7.5 MIU interleukin-2

Increased polymorphism in the HR-1 gp41 env gene encoding the enfuvirtide (T-20) target in HIV-1 variants harboring multiple antiretroviral drug resistance mutations in the pol gene

Alteration of cytochrome oxidase subunit I labeling is associated with severe mitochondriopathy in NRTI-related hepatotoxicity in HIV patients

Sexually transmitted acute infection with a clustered genotype 4 hepatitis C virus in HIV-1-infected men and inefficacy of early antiviral therapy

HIV infection in older patients in the HAART era

Recurring acute abdominal pains in an adolescent as the presenting manifestations of hereditary angioneurotic oedema

Response to highly active antiretroviral therapy at 6 months and long-term disease progression in HIV-1 infection

Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome

Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

Sustained exacerbation of cryoglobulinaemia-related vasculitis following treatment of hepatitis C with peginterferon alfa

Dendritic cells generated in the presence of interferon-alpha stimulate allogeneic CD4+ T-cell proliferation: modulation by autocrine IL-10, enhanced T-cell apoptosis and T regulatory type 1 cells