Timeline

Hugues Aschard
Head of Structure
07 Jan 2020
publication

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

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13 Dec 2019
publication

Mixed-model admixture mapping identifies smoking-dependent loci of lung function in African Americans

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21 Nov 2019
publication

Making the Most of Clumping and Thresholding for Polygenic Scores

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12 Nov 2019
publication

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

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01 Nov 2019
publication

RAISS: robust and accurate imputation from summary statistics

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21 Oct 2019
publication

A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

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13 Sep 2019
publication

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

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20 May 2019
publication

Genetic correlations between diabetes and glaucoma: an analysis of continuous and dichotomous phenotypes

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10 Apr 2019
publication

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

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29 Mar 2019
publication

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

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08 Mar 2019
publication

Genetic effects on the commensal microbiota in inflammatory bowel disease patients

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26 Feb 2019
publication

Efficient Implementation of Penalized Regression for Genetic Risk Prediction

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29 Jan 2019
publication

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

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28 Jan 2019
publication

Adjusting for Principal Components of Molecular Phenotypes Induces Replicating False Positives

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22 Jan 2019
publication

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

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21 Dec 2018
publication

Joint Analysis of Multiple Interaction Parameters in Genetic Association Studies

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18 Dec 2018
publication

Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation

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01 Oct 2018
publication

VarExp: estimating variance explained by genome-wide GxE summary statistics

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15 Aug 2018
publication

Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr

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27 Jul 2018
publication

Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

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19 Jul 2018
software

JASS – Joint Analysis of (GWAS) Summary Statistics

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18 Jun 2018
publication

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

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27 Feb 2018
publication

lme4qtl: linear mixed models with flexible covariance structure for genetic studies of related individuals

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15 Feb 2018
publication

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

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08 Feb 2018
publication

A test for gene-environment interaction in the presence of measurement error in the environmental variable

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01 Feb 2018
publication

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

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17 Jan 2018
publication

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

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27 Dec 2017
publication

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

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08 Nov 2017
publication

An ancestry-based approach for detecting interactions

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16 Oct 2017
publication

Covariate selection for association screening in multiphenotype genetic studies

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01 Oct 2017
publication

Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases

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01 Oct 2017
publication

Update on the State of the Science for Analytical Methods for Gene-Environment Interactions

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01 Oct 2017
publication

Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions

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30 Aug 2017
publication

Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis

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01 Jun 2017
publication

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function

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16 Mar 2017
publication

Screening for interaction effects in gene expression data

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16 Mar 2017
publication

A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts

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01 Mar 2017
publication

Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women

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01 Feb 2017
publication

Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample

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25 Oct 2016
publication

Pancreatic Cancer Risk Associated with Prediagnostic Plasma Levels of Leptin and Leptin Receptor Genetic Polymorphisms

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29 Sep 2016
team

Statistical Genetics

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26 Jul 2016
publication

Genomics, Telomere Length, Epigenetics, and Metabolomics in the Nurses’ Health Studies

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07 Jul 2016
publication

A perspective on interaction effects in genetic association studies

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21 Jun 2016
publication

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

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27 May 2016
publication

An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

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18 May 2016
publication

Power Calculation of Multi-step Combined Principal Components with Applications to Genetic Association Studies

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04 Feb 2016
publication

Response to Day et al

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03 Feb 2016
publication

Fungal microbiota dysbiosis in IBD

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11 Jan 2016
publication

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

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26 Nov 2015
publication

Emergence of Antimicrobial-Resistant Escherichia coli of Animal Origin Spreading in Humans

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24 Oct 2015
publication

Leveraging local ancestry to detect gene-gene interactions in genome-wide data

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22 Jul 2015
publication

Fitness cost of antibiotic susceptibility during bacterial infection

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01 May 2015
publication

Finding the missing gene-environment interactions

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18 Mar 2015
publication

[Genetic and environmental factors of asthma and allergy: Results of the EGEA study]

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29 Jan 2015
publication

Adjusting for heritable covariates can bias effect estimates in genome-wide association studies

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01 Jan 2015
publication

Variation in predictive ability of common genetic variants by established strata: the example of breast cancer and age

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17 Apr 2014
publication

Maximizing the power of principal-component analysis of correlated phenotypes in genome-wide association studies

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18 Nov 2013
publication

Enhanced in vivo fitness of carbapenem-resistant oprD mutants of Pseudomonas aeruginosa revealed through high-throughput sequencing

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04 Nov 2013
publication

Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study

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05 Sep 2013
publication

A comprehensive analysis of in vitro and in vivo genetic fitness of Pseudomonas aeruginosa using high-throughput sequencing of transposon libraries

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19 Mar 2013
publication

A nonparametric test to detect quantitative trait loci where the phenotypic distribution differs by genotypes

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30 Jan 2013
publication

Exploring genome-wide – dietary heme iron intake interactions and the risk of type 2 diabetes

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02 Jan 2013
publication

Transcriptional response of mucoid Pseudomonas aeruginosa to human respiratory mucus

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20 Dec 2012
publication

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

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04 Jul 2012
publication

Challenges and opportunities in genome-wide environmental interaction (GWEI) studies

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24 May 2012
publication

Inclusion of gene-gene and gene-environment interactions unlikely to dramatically improve risk prediction for complex diseases

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29 Nov 2011
publication

Combining effects from rare and common genetic variants in an exome-wide association study of sequence data

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03 Feb 2011
publication

Genome-wide meta-analysis of joint tests for genetic and gene-environment interaction effects

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01 Jan 2011
publication

Inflated type I error rates when using aggregation methods to analyze rare variants in the 1000 Genomes Project exon sequencing data in unrelated individuals: summary results from Group 7 at Genetic Analysis Workshop 17

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23 Dec 2009
publication

17q21 variants modify the association between early respiratory infections and asthma

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18 Jun 2009
publication

Sex-specific effect of IL9 polymorphisms on lung function and polysensitization

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15 Oct 2008
publication

Effect of 17q21 variants and smoking exposure in early-onset asthma

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18 Dec 2007
publication

A two-step multiple-marker strategy for genome-wide association studies

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01 Jan 2007
publication

Multistage designs in the genomic era: providing balance in complex disease studies

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