Timeline

Nicolas Wolff
Group Leader
13 Oct 2020
course

Biochimie des Protéines

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02 Oct 2020
publication

Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.

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21 Sep 2020
publication

Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.

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16 Jul 2020
project

Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)

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14 Nov 2019
event

DPT NEUROSCIENCE – Thesis defence : Mariano GENERA – Structural and functional study of the human phosphatase PTPN3 and its interaction with oncogenic viruses.

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25 Jul 2019
publication

Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth

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01 Jan 2019
publication

High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay

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05 Sep 2018
publication

Structural plasticity of the HHD2 domain of whirlin

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09 Mar 2018
publication

Tuning interval Branch-and-Prune for protein structure determination

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08 Feb 2018
project

Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome

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08 Feb 2018
project

Rabies virus neuronal infection

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31 Oct 2017
publication

Interfering peptides targeting protein-protein interactions: the next generation of drugs?

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28 Sep 2017
publication

Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem

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20 May 2016
project

Role of PDZ-binding motif from Flavivirus non-structural proteins in flaviviral life cycle

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09 Sep 2015
tool

Nuclear Magnetic Resonance spectrometers

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16 Jul 2015
team

Signalling and Molecular interactions

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08 Jun 2015
publication

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay

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05 May 2015
publication

Deciphering the unconventional peptide binding to the PDZ domain of MAST2

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05 Mar 2015
publication

Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus

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18 Oct 2014
publication

Quantitative and dynamic analysis of PTEN phosphorylation by NMR

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30 Sep 2014
publication

Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain

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21 Sep 2014
team

Channel Receptors

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01 Jul 2014
publication

A unified nomenclature and amino acid numbering for human PTEN

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07 Dec 2012
publication

Ordered phosphorylation events in two independent cascades of the PTEN C-tail revealed by NMR

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14 Jun 2012
publication

Role of the iron axial ligands of heme carrier HasA in heme uptake and release

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12 Oct 2011
publication

Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death

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13 Jan 2009
publication

1H, 13C and 15N resonance assignments of the PDZ of microtubule-associated serine/threonine kinase 205 (MAST205) in complex with the C-terminal motif from the rabies virus glycoprotein

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04 Dec 2007
publication

Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications

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18 Apr 2006
publication

Structural and functional characterization of the TgDRE multidomain protein, a DNA repair enzyme from Toxoplasma gondii

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01 Aug 2004
publication

Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels

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26 Jun 2003
publication

Antifolding activity of the SecB chaperone is essential for secretion of HasA, a quickly folding ABC pathway substrate

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01 Apr 2002
publication

Histidine pK(a) shifts and changes of tautomeric states induced by the binding of gallium-protoporphyrin IX in the hemophore HasA(SM)

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