Ligne de temps
Nicolas Wolff
Chef(fe) de Groupe
31 juil. 2023
26 juil. 2023
publication
Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.
Lire plus01 janv. 2023
publication
Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Lire plus01 janv. 2022
publication
Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Lire plus01 janv. 2022
publication
Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.
Lire plus15 nov. 2021
30 sept. 2021
23 juin 2021
event
Internal Seminar Dept Neuroscience “Molecular organization and regulation of the Usher2 complex, a protein assembly related to deafness and blindness”, Nicolas Wolff
Lire plus17 avr. 2021
14 avr. 2021
05 févr. 2021
publication
Role of PDZ-binding motif from West Nile virus NS5 protein on viral replication.
Lire plus13 janv. 2021
publication
Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein.
Lire plus01 janv. 2021
01 janv. 2021
publication
PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations.
Lire plus08 déc. 2020
publication
Ultrarare heterozygous pathogenic variants of genes causing dominant forms of early-onset deafness underlie severe presbycusis.
Lire plus06 nov. 2020
publication
Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
Lire plus13 oct. 2020
02 oct. 2020
publication
Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.
Lire plus18 août 2020
publication
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate.
Lire plus16 juil. 2020
project
Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)
Lire plus14 nov. 2019
event
DPT NEUROSCIENCE – Thesis defence : Mariano GENERA – Structural and functional study of the human phosphatase PTPN3 and its interaction with oncogenic viruses.
Lire plus25 juil. 2019
publication
Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth
Lire plus01 janv. 2019
publication
High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay
Lire plus05 sept. 2018
09 mars 2018
08 févr. 2018
project
Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome
Lire plus08 févr. 2018
31 oct. 2017
publication
Interfering peptides targeting protein-protein interactions: the next generation of drugs?
Lire plus28 sept. 2017
publication
Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem
Lire plus09 sept. 2015
16 juil. 2015
08 juin 2015
publication
Quantifying domain-ligand affinities and specificities by high-throughput holdup assay
Lire plus05 mai 2015
05 mars 2015
publication
Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus.
Lire plus18 oct. 2014
30 sept. 2014
publication
Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.
Lire plus21 sept. 2014
01 juil. 2014
07 déc. 2012
publication
Ordered phosphorylation events in two independent cascades of the PTEN C-tail revealed by NMR
Lire plus12 oct. 2011
publication
Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death
Lire plus13 janv. 2009
publication
1H, 13C and 15N resonance assignments of the PDZ of microtubule-associated serine/threonine kinase 205 (MAST205) in complex with the C-terminal motif from the rabies virus glycoprotein
Lire plus04 déc. 2007
publication
Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications
Lire plus18 avr. 2006
publication
Structural and functional characterization of the TgDRE multidomain protein, a DNA repair enzyme from Toxoplasma gondii
Lire plus01 août 2004
publication
Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels
Lire plus26 juin 2003
publication
Antifolding activity of the SecB chaperone is essential for secretion of HasA, a quickly folding ABC pathway substrate
Lire plus01 avr. 2002
publication