Timeline

Ludovic Sauguet
Permanent Researcher
20 Jan 2021
project

DNA Replisome in Archaea

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02 Dec 2020
publication

Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases.

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27 Mar 2020
publication

Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.

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20 Sep 2019
publication

The Extended “Two-Barrel” Polymerases Superfamily: Structure, Function and Evolution

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18 Sep 2019
event

Department of Structural Biology and Chemistry Department: Prof. Xiadong Zhang, Structures and Mechanisms of Transcription Initiation and Regulation

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18 Jan 2019
publication

Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

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18 Jan 2019
publication

Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

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15 Jan 2019
publication

An updated structural classification of replicative DNA polymerases

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12 Dec 2018
publication

Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel

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24 Apr 2018
publication

Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels

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09 Apr 2018
publication

Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation

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01 Oct 2016
publication

Vaccination Against Human Papilloma Viruses Leads to a Favorable Cytokine Profile of Specific T Cells

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22 Aug 2016
publication

Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography.

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15 Jun 2016
publication

Neurotoxic phospholipase A2 from rattlesnake as a new ligand and new regulator of prokaryotic receptor GLIC (proton-gated ion channel from G. violaceus).

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24 Mar 2016
publication

Sites of Anesthetic Inhibitory Action on a Cationic Ligand-Gated Ion Channel

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24 Feb 2016
publication

Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel

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11 May 2015
team

Architecture and Dynamics of Biological Macromolecules

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03 Mar 2015
publication

Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure.

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14 May 2014
publication

Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels

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23 Dec 2013
publication

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation

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12 Feb 2013
publication

Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels

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01 Jan 2013
publication

Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel

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03 Oct 2012
publication

Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines

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06 Jun 2012
publication

Structure and pharmacology of pentameric receptor channels: from bacteria to brain

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13 May 2012
publication

A locally closed conformation of a bacterial pentameric proton-gated ion channel

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