Timeline

Spencer Shorte

Head of Structure

07 Jan 2023

publication

Deep learning in image-based phenotypic drug discovery.

07 Dec 2021

news

New two-photon microscope open for new projects at Photonic Bio Imaging Facility

07 Dec 2021

news

New Super Resolution microscope open for new projects at Photonic Bio Imaging at PBI

02 Jul 2021

publication

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.

01 Jan 2021

publication

Corrigendum: Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

01 Jan 2020

publication

Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

25 Oct 2018

publication

Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting.

03 Jul 2018

center

Center for Technological Resources and Research

12 Apr 2018

software

MaMuT

29 Mar 2018

publication

Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb.

06 Mar 2018

publication

Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy.

01 Mar 2018

publication

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

16 Jan 2018

publication

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.

29 Nov 2017

software

TrackMate

17 Aug 2017

team

Photonic BioImaging (UTechS PBI)

15 Feb 2017

publication

TrackMate: An open and extensible platform for single-particle tracking.

01 Jan 2017

publication

Assessing Vacuolar Escape of Listeria Monocytogenes

06 Sep 2016

publication

Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses.

10 Apr 2016

tool

Dual microscopy assay to discriminate Listeria cellular entry & vacuolar escape

07 Sep 2015

project

FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)

27 Feb 2015

publication

Spatially resolved contrast measurement of diffractive micromirror arrays

25 Feb 2015

project

Development and Application of new Molecular Probes

25 Jan 2015

publication

Spatio-angular light control in microscopes using micro mirror arrays

25 Jan 2015

publication

A new method to achieve tens of nm axial super-localisation based on conical diffraction PSF shaping

11 Dec 2014

publication

Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus

08 Oct 2014

publication

Shigella subverts the host recycling compartment to rupture its vacuole

28 Aug 2014

publication

Conical diffraction as a versatile building block to implement new imaging modalities for superresolution in fluorescence microscopy

06 Aug 2014

publication

High-throughput monitoring of major cell functions by means of lensfree video microscopy

23 May 2014

publication

A step beyond BRET: Fluorescence by Unbound Excitation from Luminescence (FUEL)

16 Apr 2014

publication

Silencing the radicals improves Click Chemistry

15 Mar 2014

publication

In vitro characterization of Fluorescence by Unbound Excitation from Luminescence: broadening the scope of energy transfer.

01 Mar 2014

publication

Real-time label-free detection of dividing cells by means of lensfree video-microscopy

01 Mar 2014

publication

Objective comparison of particle tracking methods.

01 Jan 2014

publication

Conical diffraction illumination opens the way for low phototoxicity super-resolution imaging.

01 Jan 2014

publication

In vitro and in vivo demonstrations of Fluorescence by Unbound Excitation from Luminescence (FUEL)

23 May 2013

publication

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.

08 Mar 2013

publication

Micro mirror arrays as high-resolution spatial light modulators for photoactivation and optogenetics

21 May 2012

publication

In vivo excitation of nanoparticles using luminescent bacteria

01 Jan 2012

publication

A quantitative method for measuring phototoxicity of a live cell imaging microscope.

06 Dec 2010

publication

Confocal bi-protocol: a new strategy for isotropic 3D live cell imaging

01 Jun 2009

publication

Perspective: Hidden treasures from the archives

01 Jun 2009

publication

Retrospective: Birth of the cool – imaging and microbiology from Ibn al-Haytham to Jean Comandon

01 Mar 2009

publication

Isotropic high-resolution three-dimensional confocal micro-rotation imaging for non-adherent living cells

01 May 2008

publication

Electron-multiplying charge-coupled detector-based bioluminescence recording of single-cell Ca2+

13 Mar 2008

publication

Three-dimensional FRET reconstruction microscopy for analysis of dynamic molecular interactions in live cells

01 Feb 2008

publication

A Bayesian reconstruction method for micro-rotation imaging in light microscopy

01 Jan 2008

publication

High-resolution 3-D imaging of living cells in suspension using confocal axial tomography

07 Jun 2007

publication

The SPI-2 type III secretion system restricts motility of Salmonella-containing vacuoles

30 Mar 2007

publication

Over-expression of Leishmania major MAP kinases reveals stage-specific induction of phosphotransferase activity

01 Jan 2007

publication

In vivo imaging of malaria parasites in the murine liver

01 Jan 2007

publication

Imaging malaria sporozoites in the dermis of the mammalian host

01 Oct 2006

publication

Quantitative four-dimensional tracking of cytoplasmic and nuclear HIV-1 complexes

17 Aug 2006

publication

Quantitative imaging of Plasmodium sporozoites in the mammalian host

01 Jun 2006

publication

Quantitative real-time analysis of HIV-1 gene expression dynamics in single living primary cells

23 May 2006

publication

Actin polymerisation at the cytoplasmic face of eukaryotic nuclei

09 May 2006

publication

Imaging today’s infectious animalcules

22 Jan 2006

publication

Quantitative imaging of Plasmodium transmission from mosquito to mammal

01 Jun 2005

publication

Use of micro-rotation imaging to study JNK-mediated cell survival in Theileria parva-infected B-lymphocytes

08 Apr 2005

publication

Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites.

01 Feb 2005

publication

Visualization of local Ca2+ dynamics with genetically encoded bioluminescent reporters

01 Jul 2004

publication

Imaging movement of malaria parasites during transmission by Anopheles mosquitoes

01 Apr 2004

publication

Focusing light on infection in four dimensions

15 Oct 2002

publication

Cloning and mRNA expression of the Ca2+-binding DREAM protein in the pituitary

01 Mar 2002

publication

PRL gene expression in individual living mammotropes displays distinct functional pulses that oscillate in a noncircadian temporal pattern

01 Dec 2001

publication

Pulsatile exocytosis is functionally associated with GnRH gene expression in immortalized GnRH-expressing cells

01 May 2001

publication

Synchronized exocytotic bursts from gonadotropin-releasing hormone-expressing cells: dual control by intrinsic cellular pulsatility and gap junctional communication

01 Sep 2000

publication

Spontaneous calcium oscillatory patterns in mammotropes display non-random dynamics

01 Jun 1999

publication

Functional integrity of green fluorescent protein conjugated glycine receptor channels

01 Aug 1997

publication

N-methyl-D-aspartate evokes rapid net depolymerization of filamentous actin in cultured rat cerebellar granule cells

01 Jan 1996

publication

The effect of extracellular polyvalent cations on bovine anterior pituitary cells. Evidence for a Ca(2+)-sensing receptor coupled to release of intracellular calcium stores

01 Nov 1995

publication

Simultaneous measurement of [Ca2+]i and secretion-coupled membrane turnover, by single cell fluorescence microscopy

01 Oct 1993

publication

Thyroliberin-induced changes in the fluorescence of a membrane probe in individual bovine anterior pituitary cells

01 Feb 1993

publication

Use of a fluorescent dye to measure secretion from intact bovine anterior pituitary cells

01 Aug 1991

publication

Thyrotropin-releasing hormone-induced cytosolic calcium transients: characterisation of store refilling in bovine anterior pituitary cells

01 Apr 1991

publication

A little guide for advanced search:

Deep learning in image-based phenotypic drug discovery.

New two-photon microscope open for new projects at Photonic Bio Imaging Facility

New Super Resolution microscope open for new projects at Photonic Bio Imaging at PBI

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.

Corrigendum: Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting.

Center for Technological Resources and Research

MaMuT

Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb.

Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy.

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.

TrackMate

Photonic BioImaging (UTechS PBI)

TrackMate: An open and extensible platform for single-particle tracking.

Assessing Vacuolar Escape of Listeria Monocytogenes

Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses.

Dual microscopy assay to discriminate Listeria cellular entry & vacuolar escape

FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)

Spatially resolved contrast measurement of diffractive micromirror arrays

Development and Application of new Molecular Probes

Spatio-angular light control in microscopes using micro mirror arrays

A new method to achieve tens of nm axial super-localisation based on conical diffraction PSF shaping

Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus

Shigella subverts the host recycling compartment to rupture its vacuole

Conical diffraction as a versatile building block to implement new imaging modalities for superresolution in fluorescence microscopy

High-throughput monitoring of major cell functions by means of lensfree video microscopy

A step beyond BRET: Fluorescence by Unbound Excitation from Luminescence (FUEL)

Silencing the radicals improves Click Chemistry

In vitro characterization of Fluorescence by Unbound Excitation from Luminescence: broadening the scope of energy transfer.

Real-time label-free detection of dividing cells by means of lensfree video-microscopy

Objective comparison of particle tracking methods.

Conical diffraction illumination opens the way for low phototoxicity super-resolution imaging.

In vitro and in vivo demonstrations of Fluorescence by Unbound Excitation from Luminescence (FUEL)

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.

Micro mirror arrays as high-resolution spatial light modulators for photoactivation and optogenetics

In vivo excitation of nanoparticles using luminescent bacteria

A quantitative method for measuring phototoxicity of a live cell imaging microscope.

Confocal bi-protocol: a new strategy for isotropic 3D live cell imaging

Perspective: Hidden treasures from the archives

Retrospective: Birth of the cool – imaging and microbiology from Ibn al-Haytham to Jean Comandon

Isotropic high-resolution three-dimensional confocal micro-rotation imaging for non-adherent living cells

Electron-multiplying charge-coupled detector-based bioluminescence recording of single-cell Ca2+

Three-dimensional FRET reconstruction microscopy for analysis of dynamic molecular interactions in live cells

A Bayesian reconstruction method for micro-rotation imaging in light microscopy

High-resolution 3-D imaging of living cells in suspension using confocal axial tomography

The SPI-2 type III secretion system restricts motility of Salmonella-containing vacuoles

Over-expression of Leishmania major MAP kinases reveals stage-specific induction of phosphotransferase activity

In vivo imaging of malaria parasites in the murine liver

Imaging malaria sporozoites in the dermis of the mammalian host

Quantitative four-dimensional tracking of cytoplasmic and nuclear HIV-1 complexes

Quantitative imaging of Plasmodium sporozoites in the mammalian host

Quantitative real-time analysis of HIV-1 gene expression dynamics in single living primary cells

Actin polymerisation at the cytoplasmic face of eukaryotic nuclei

Imaging today’s infectious animalcules

Quantitative imaging of Plasmodium transmission from mosquito to mammal

Use of micro-rotation imaging to study JNK-mediated cell survival in Theileria parva-infected B-lymphocytes

Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites.

Visualization of local Ca2+ dynamics with genetically encoded bioluminescent reporters

Imaging movement of malaria parasites during transmission by Anopheles mosquitoes

Focusing light on infection in four dimensions

Cloning and mRNA expression of the Ca2+-binding DREAM protein in the pituitary

PRL gene expression in individual living mammotropes displays distinct functional pulses that oscillate in a noncircadian temporal pattern

Pulsatile exocytosis is functionally associated with GnRH gene expression in immortalized GnRH-expressing cells

Synchronized exocytotic bursts from gonadotropin-releasing hormone-expressing cells: dual control by intrinsic cellular pulsatility and gap junctional communication

Spontaneous calcium oscillatory patterns in mammotropes display non-random dynamics

Functional integrity of green fluorescent protein conjugated glycine receptor channels

N-methyl-D-aspartate evokes rapid net depolymerization of filamentous actin in cultured rat cerebellar granule cells

The effect of extracellular polyvalent cations on bovine anterior pituitary cells. Evidence for a Ca(2+)-sensing receptor coupled to release of intracellular calcium stores

Simultaneous measurement of [Ca2+]i and secretion-coupled membrane turnover, by single cell fluorescence microscopy

Thyroliberin-induced changes in the fluorescence of a membrane probe in individual bovine anterior pituitary cells

Use of a fluorescent dye to measure secretion from intact bovine anterior pituitary cells

Thyrotropin-releasing hormone-induced cytosolic calcium transients: characterisation of store refilling in bovine anterior pituitary cells

Ammonium ions mobilize calcium from an internal pool which is insensitive to TRH and ionomycin in bovine anterior pituitary cells