Timeline

Timothy Wai
Head of Structure
26 Aug 2019
event

BCI Seminar – “Cytoskeletal cross-talk with integrin adhesion complexes in cell morphogenesis”

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01 Jan 2019
publication

Loss of the mitochondrial -AAA protease YME1L leads to ocular dysfunction and spinal axonopathy

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03 Jun 2018
project

Fat4Heart ERA-CVD 2016

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02 Jun 2018
project

Mitomorphosis ERC-StG 2016

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01 Jun 2018
team

Mitochondrial Biology

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01 Aug 2017
publication

Lung ultrasound as a translational approach for non-invasive assessment of heart failure with reduced or preserved ejection fraction in mice

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13 Oct 2016
publication

The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L

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06 Aug 2016
publication

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

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02 Jan 2016
publication

Mitochondrial Dynamics and Metabolic Regulation

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04 Dec 2015
publication

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

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06 Aug 2015
publication

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

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16 Mar 2015
publication

Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function

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12 Feb 2015
publication

The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis

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10 Mar 2014
publication

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

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06 Aug 2013
publication

TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid

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07 Oct 2012
publication

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

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14 Oct 2010
publication

Gimap3 regulates tissue-specific mitochondrial DNA segregation

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03 Mar 2010
publication

LRPPRC and SLIRP interact in a ribonucleoprotein complex that regulates posttranscriptional gene expression in mitochondria

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03 Feb 2010
publication

The role of mitochondrial DNA copy number in mammalian fertility

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01 Dec 2008
publication

The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

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15 Feb 2008
publication

Medicine. Sidestepping mutational meltdown

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01 Jan 2007
publication

Mitochondrial DNA and the mammalian oocyte

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09 Jun 2006
publication

A hemizygous SCO2 mutation in an early onset rapidly progressive, fatal cardiomyopathy

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01 Dec 2004
publication

Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism

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15 Dec 2002
publication

Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria

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