Ligne de temps
Timothy Wai
Responsable de Structure
11 avr. 2025
event
BCI & BSC joint Seminar – “Conformational flexibility and molecular plasticity in herpesvirus entry and egress”
Lire plus01 oct. 2024
11 juin 2024
publication
Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling.
Lire plus20 déc. 2023
news
New publication – Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis
Lire plus20 déc. 2023
publication
Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis.
Lire plus10 oct. 2023
project
MitoDeath: Dissecting the molecular mechanisms responsible for a mitochondrial defect leading to motor neuron death (FRM)
Lire plus10 oct. 2023
project
IMHOTEP: Role of hepatocyte mitochondrial dysfunction in the occurrence and progression of NAFLD (ANR)
Lire plus10 oct. 2023
project
MitoCure: Mitochondrial Disease Platform-Institut Pasteur (ArgoBIO et Institut Pasteur)
Lire plus01 mars 2023
publication
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Lire plus20 févr. 2023
01 févr. 2023
01 févr. 2023
event
BCI Seminar – “Deciphering the spatiotemporal and mechanical regulation of integrin and actin regulators at the nanoscale”
Lire plus03 janv. 2023
news
New publication – Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure
Lire plus01 janv. 2023
publication
Mitochondrial dynamics and metabolic regulation control T cell fate in the thymus.
Lire plus04 nov. 2022
publication
Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure.
Lire plus21 oct. 2022
publication
CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability.
Lire plus09 mai 2022
event
Combination of spectroscopy with microscopy enables new dimensions in quantitative biology – Leonel Malacrida, IP Montevideo
Lire plus06 avr. 2022
09 nov. 2021
publication
Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling.
Lire plus18 oct. 2021
04 oct. 2021
publication
Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A.
Lire plus07 juin 2021
publication
High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts.
Lire plus27 mai 2021
news
Mitochondrial diseases: a new screening leads to insight on the effect of various genes on DOA
Lire plus01 mai 2021
05 avr. 2021
01 janv. 2021
publication
Mitochondrial Nucleic Acid as a Driver of Pathogenic Type I Interferon Induction in Mendelian Disease.
Lire plus26 août 2019
event
BCI Seminar – “Cytoskeletal cross-talk with integrin adhesion complexes in cell morphogenesis”
Lire plus01 janv. 2019
publication
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
Lire plus03 juin 2018
01 juin 2018
01 août 2017
publication
Lung ultrasound as a translational approach for non-invasive assessment of heart failure with reduced or preserved ejection fraction in mice
Lire plus13 oct. 2016
publication
The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L
Lire plus06 août 2016
publication
Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation
Lire plus02 janv. 2016
04 déc. 2015
publication
Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice
Lire plus06 août 2015
publication
SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation
Lire plus16 mars 2015
publication
Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function
Lire plus12 févr. 2015
publication
The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis
Lire plus10 mars 2014
publication
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
Lire plus06 août 2013
publication
TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid
Lire plus07 oct. 2012
publication
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission
Lire plus14 oct. 2010
03 mars 2010
publication
LRPPRC and SLIRP interact in a ribonucleoprotein complex that regulates posttranscriptional gene expression in mitochondria
Lire plus03 févr. 2010
01 déc. 2008
publication
The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes
Lire plus15 févr. 2008
01 janv. 2007
09 juin 2006
publication
A hemizygous SCO2 mutation in an early onset rapidly progressive, fatal cardiomyopathy
Lire plus01 déc. 2004
publication
Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism
Lire plus15 déc. 2002
publication