The research conducted at UMR 3569 aligns closely with the strategic priorities of the Institut CNRS Biology. It focuses on fundamental virology, with the overarching goal of deepening our understanding of viral emergence and the pathogenesis of viral infections. We study viruses of significant public health concern, including coronaviruses, influenza viruses, enteroviruses, and arboviruses, and we investigate the full replication cycle — from viral entry to the release of progeny virions — alongside host immune responses and viral evasion strategies. Our research integrates diverse experimental methodologies, such as molecular biology, genetics, biochemistry, structural biology, omics technologies, and advanced imaging.
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Connections
Groups
Laboratory

Structural Virology

Félix A. Rey
Laboratory

RNA Biology of Influenza Virus

Nadia Naffakh
Laboratory

Virus sensing and signaling

Nolwenn Jouvenet
Members
Fundings
Publications
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2025Squirrel reservoirs of monkeypox virus are sister species separated by the Sanaga River (Cameroon), as are the two main viral clades., One Health 2025 Dec; 21(): 101157.
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2025LRP8 is a receptor for tick-borne encephalitis virus., Nature 2025 Sep; (): .
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2025Antibody cross-reactivity among alphaviruses clinical practice., Trends Microbiol 2025 Aug; (): .
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2025Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious., Nat Commun 2025 Aug; 16(1): 7491.
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2025Adaptive immune responses to SARS-CoV-2 in DMARD-treated patients with chronic inflammatory rheumatisms., RMD Open 2025 Jul; 11(3): .
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2025Modulation of SARS-CoV-2 spike binding to ACE2 through conformational selection., Nat Nanotechnol 2025 Jul; 20(7): 926-934.
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2025Influenza A virus induces PI4P production at the endoplasmic reticulum in an ATG16L1-dependent manner to promote the egress of viral ribonucleoproteins., PLoS Biol 2025 Jul; 23(7): e3002958.
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2025Use of Recombinant Chikungunya Virus expressing Nanoluciferase to Identify Chondrocytes as Target Cells in an Immunocompetent Mouse Model, Journal of Infectious Diseases, In press, pp.jiaf232. ⟨10.1093/infdis/jiaf232⟩.
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2025A MERS-CoV-like mink coronavirus uses ACE2 as an entry receptor., Nature 2025 Jun; 642(8068): 739-746.
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2025Toward a deeper understanding of dengue: novel method for quantification and isolation of envelope protein epitope-specific antibodies., mSphere 2025 May; 10(5): e0096124.
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