Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
Scientific Fields
Diseases
Organisms
Applications
Technique

About

Bacteria are remarkable models for biology and have phenotypic characteristics of great cognitive, health or biotechnological values. Most bacteria are constantly exposed to fluctuating environments, thus are ideally set to detect, react and adapt to various stress conditions. The Pasteur unit “Adaptation to stress and metabolism of enterobacteria” aims to understand the stress response at the populational, cellular and molecular level. Our unit comprises 12 scientists, including Pasteur and CNRS researchers , engineers and technicians, post-docs and students.
We study how a wide range of basic functional processes are modified, and possibly coordinated, to control cellular homeostasis. Our research mainly uses E. coli as a model, but concepts will be as well tested on pathogens such as Salmonella or Shigella. Focusing on two global cellular processes, Fe-S cluster biogenesis and lipid homeostasis, allows us to study the impact of stress on aerobic and anaerobic metabolism, cell envelope and membrane homeostasis, redox changes, limitation of nutrients, metabolic and antibiotics stresses.
Molecular, biochemical and genetic approaches, as well as cutting-edge technologies (-omics, imaging, single-cell analysis), aim to achieve an integrated and mechanistic vision of the bacterial cell. To multiply and diversify the ways to approach a process is very rewarding, and we collaborate with biochemists, structuralists, chemists, biophysicists, bioinformaticians and phylogeneticists.

Former Members

2000
2000
Name
Position
2018
2020
Alessandra Lo Sciuto
Post-doc

Publications

Download