Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinician Researcher
  • Department Manager
  • Full Professor
  • Graduate Student
  • Honorary Professor
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinician Researcher
  • Department Manager
  • Full Professor
  • Graduate Student
  • Honorary Professor
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share

About

The Metabolomics Core Facility (MCF) was created on December 1st, 2020 and is part of the Center for Technological Resources and Research (C2RT) and the Microbiology Department.

The main objective of the platform is to provide researchers with metabolomic strategies to help them answer their biological questions. The metabolomic team will support researchers from the definition of experimental design to the interpretation of the results. They benefit from state-of-the-art instrumentation and computational methods. It includes the latest generation of high speed, high-resolution mass spectrometers as well as bioinformatics and statistical tools to analyze the complex high-dimensional data generated.

Our activities

Large-scale metabolomic and lipidomic analyses can provide with important information about many cellular processes and their disturbances:

  • comparison of metabolomes between several biological systems allows genotypes and phenotypes to be linked.
  • comparison of metabolomes within the same group of biological systems under different conditions enables to elucidate the influence of the environment on the expressed phenotype.

One of the main challenges of these analyses is to be able to measure metabolites with extremely diverse physico-chemical properties whilst we have not an exhaustive knowledge of all existing metabolites yet. One of the specificities of the platform is to elucidate on a large scale these unknown compounds for a fine understanding of cellular physiological mechanisms.

The main goal of the platform is to help researchers by conducting metabolomic experiments and analyses. Our activity can be divided into 3 main project types:

  • Help researchers answer their biological questions: projects submitted by Pasteur or external teams
  • Internal developments: MCF-specific projects to acquire new approaches in metabolomics and to anticipate the future needs of the Institut Pasteur
  • Transversal technological research with other internal or external teams (platforms, research units)

We are also eager to give advice and help researchers elaborate their metabolomic projects.

Do not hesitate to contact us at metabolomics@pasteur.fr if you have any question.

How to work with us

Metabolomic analyses can be long processes, and their objectives must be well defined prior to any work at the bench. The experimental design is particularly critical to make sure the results obtained are robust enough and unbiased with regards to your biological question. Sample preparation, data acquisition and analysis method must be carefully planned in advance.

In this context, feel free to email us metabolomics@pasteur.fr  and we will be happy to discuss about your needs.

Note that an online submission form is being developed in collaboration with the Bioinformatics and Biostatistics Hub and will be available soon.

 

Practical information

We are part of the C2RT (Center for Technological Resources and Research), a center encompassing the Technology and Service units (UTechS) and the technological core facilities of the campus. As such, we follow the common guidelines and good practices (click here for french version) regarding costs, communication, acknowledgments and authorship.

C2RT Booklet

Invoicing

Users agree to pay the service fees related to the facility activities. The billing policy of the platform has been built following the C2RT recommendations and with the help of the financial services. A quote will be edited after the first discussions and before any analyses at the bench.

Certification

We plan to obtain the Quality Management System norm ISO-9001:2015 early 2023.

Steering committee

David Touboul, CNRSSerge Rudaz, Université de Genève, Timothy Wai, Institut Pasteur, Anna Kehres, Institut Pasteur, Gérard Eberl, Institut Pasteur, Marie-Agnès Dillies, Institut Pasteur

 

Equipments

Note that our machines are fully dedicated to the projects of the platform and are not accessible to autonomous users.

Orbitrap Exploris 120 Mass Spectrometer • ThermoFisher Scientific • Exploris 120

The Thermo Scientific™ Orbitrap Exploris™ 120 high resolution mass spectrometer can be used for both method development and everyday testing analyses (metabolomics and lipidomics) and as well from exploratory to targeted quantitation experiments.   […]

Orbitrap IQx Mass Spectrometer • ThermoFisher Scientific • Orbitrap IQx

Built specifically for small molecule analysis, the Thermo Scientific™ Orbitrap IQ-X™ Tribrid™ high resolution mass spectrometer utilizes technology that significantly augments unknown analysis capabilities in metabolite identification (Met-ID), untargeted metabolomics, and lipidomics research, but […]

Fundings

Partners

Contact

Metabolomics Core Facility, Institut Pasteur Centre François Jacob – building 27 (Volont), 2nd floor, 28 Rue du Docteur Roux 75015, Paris France

Phone : +33 1 45 68 84 90

Email: metabolomics@pasteur.fr