The timsTOF fleX brings a spatial dimension to meltabolomics analyses
Dual source (MALDI / ESI) design to match PASEF® empowered LC-MS/MS identification with label-free spatial localization to decode the molecular make up of sample
Applicable for examining a wide range of analytes, including metabolites, lipids or glycans, and seamlessly compatible with microscopy workflows, MALDI Imaging can identify regionally specific compound distributions. The timsTOF fleX combines 4D-Omics with Bruker’s cutting edge MALDI Imaging technology, including smartbeam 3D laser optics to be a fast measurement all in one platform. A dual source instrument, timsTOF fleX conducts robust ESI measurements and spatially resolves a wide range of molecules directly from tissue using one platform. MALDI / ESI workflows can take advantage of the most advanced features found in the timsTOF HT, including trapped ion mobility separation (TIMS) based on the collisional cross section (CCS) of detected molecules to provide identification support of unknown compounds.