Members
Former Members
2000
2000
Name
Position
2015
2018
Biology of Malaria targets and Antimalarials
2015
2018
Lucile Le Chevalier-Sontag
Technician
Fundings
Partners
Publications
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2014Computational design of protein-based inhibitors of Plasmodium vivax subtilisin-like 1 protease, PLoS ONE 2014;9(10):e109269.
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2014A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity, Eur J Med Chem 2015 Jan;89:386-400.
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2014A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase, Nat Commun 2014 Sep;5:4833.
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2014Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study, Malar. J. 2014;13:110.
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2014Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens., PLoS One 2014 ; 9(1): e86658.
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2013A molecular marker of artemisinin-resistant Plasmodium falciparum malaria, Nature 2014 Jan;505(7481):50-5.
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2013A key role for Plasmodium subtilisin-like SUB1 protease in egress of malaria parasites from host hepatocytes, J. Biol. Chem. 2013 Nov;288(46):33336-46.
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2013In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound, J. Biol. Chem. 2013 Jun;288(25):18561-73.
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2013Screening and evaluation of inhibitors of Plasmodium falciparum merozoite egress and invasion using cytometry, Methods Mol. Biol. 2013;923:523-34.
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2012Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia, Antimicrob. Agents Chemother. 2013 Feb;57(2):914-23.
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Contact
Phone: + 33 1 40 61 33 72
Email: jean-christophe.barale@pasteur.fr
Address
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75015, Paris
France