Project
Organic Chemistry [75]
Project
FlexBiVac
Laurence Mulard
Laboratory
Bioorganic chemistry of nucleic acids
Marcel Hollenstein
Project
A synthetic glycopeptide for anti-tumor immunotherapy: from design to first use in human
Sylvie Bay
Project
CarbUniVax
Laurence Mulard
Epartner
Serge Van Calenbergh
Tool
Nuclear Magnetic Resonance spectrometers
Muriel Delepierre • Iñaki Guijarro • Florence Cordier • Nicolas Wolff • Nadia Izadi-Pruneyre • Bruno Vitorge
Project
Inhibitors of TMPK from Mycobacterium tuberculosis
Hélène Munier-Lehmann • Sylvie Pochet
Project
Design and optimization of new bioluminescent systems better-suited to in cellulo and in vivo conditions
Project
Inhibitors of the 2’-deoxyribonucleotide N-hydrolase DNPH1, an enzyme involved in cellular growth and angiogenesis
Sylvie Pochet • Pierre Alexandr Kaminski
Project
Alkoxypyrazoles, inhibitors of dihydroorotate dehydrogenase (DHODH)
Project
Alkoxypyrazoles, new chemical entities
Group
Group: Biochemistry and chemobiology
Hélène Munier-Lehmann
2015
Publication
Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)
Journal of medicinal chemistry
Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YLTechnician
Christelle Ganneau
Chemistry of Biomolecules
Technician