Protein conjugates for the diagnosis of Alzheimer’s disease
Development of specific imaging nanoprobes against intracerebral targets is a challenging field of research, particularly for the diagnosis of neurodegenerative diseases. Probes based on camelid single-domain antibody-fragments (VHHs or nanobodies) are promising tools due […]
A synthetic glycopeptide for anti-tumor immunotherapy: from design to first use in human
Within the framework of developing a carbohydrate-based vaccine against cancer, we designed and prepared the MAG-Tn3, a fully synthetic immunogen based on the tumor-associated Tn antigen. The MAG-Tn3 is a glycopeptide associating Tn clusters […]
2017Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide, Mol Microbiol. 2017 Aug;105(4); 525-539.
2017Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Organic & Biomolecular Chemistry, 2017, 15, 114 - 123.
2016Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Org. Biomol. Chem. 2016 Dec;15(1):114-123.
2015New tools for amyloid plaques detection by MRI: Gadolinium-VHH antibody conjugates, 2014; 10, Supplement, P14–P15.
2009Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide, ChemMedChem 2009 Apr;4(4):582-7.