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  • patent
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  • Assistant Professor
  • Associate Professor
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  • Clinician Researcher
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  • Honorary Professor
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  • PhD Student
  • Physician
  • Post-doc
  • Prize
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  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
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© Laurent Debarbieux
Bactériophages sur la bactérie Escherichia coli 0104:H4 souche 55989.

Projects

Project
Completed
16 Members

Oncobiomics – THE (heterogenity tumor ecosystem)

Marc Monot (PI)

The Oncobiomics project is conducted in the HTE (heterogenity tumor ecosystem) national program launched by the cancer nation institute (Inca) in the third national cancer plan 2014-2019. It’s a consortium project involving 8 teams […]
Project
Ongoing
5 Members

Identification of a « crypt-specific core microbiota, CSCM » in human and murine intestine

Thierry Pedron (PI)

In an attempt to explore the microbial content of colonic crypts of the mouse gut that contain the stem cells, thereby accounting for epithelial regeneration, we proceeded to targeted molecular microbial diagnostic. We showed […]
Project
Ongoing
5 Members

Virulents bacteriophages and microbial ecosystems

Laurent Debarbieux (PI)

Digestive tract of mammals is one of the most complex microbial ecosystems subject to both external and internal factors, through food consumption and interactions with intestinal cells. We are developing and using several experimental […]

CV

My research started in 1984 in the Unité d’Immunophysiologie Moléculaire directed by Guy Bordenave (Institut Pasteur, Paris), where I worked under the supervision of Robert Girard on the interactions of the lipopolysaccharides with the immune cells.

In 2001, I joined the Unité de Pathogénie Microbienne Moléculaire directed by Philippe Sansonetti (Institut Pasteur, Paris), where I first investigated the modulation of the intestinal epithelial gene expression during Shigella flexneri infection. My work is now focused on commensal bacteria. A few years ago, we analysed the anti-inflammatory properties of Lactobacilli strains. I am characterizing the crypt-specific core microbiota in human and murine intestinal tissues and their variation during dysbiosis.

Publications

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