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2023Generation of embryo-like structures from mouse embryonic stem cells treated with a chemical inhibitor of SUMOylation and cultured in microdroplets, STAR Protoc . 2023 Sep 17;4(4):102573.
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2023Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures, Cell Rep . 2023 Apr 15;42(4):112380. doi: 10.1016/j.celrep.2023.112380.
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2021ddPCR increases detection of SARS-CoV-2 RNA in patients with low viral loads., Arch Virol 2021 Sep; 166(9): 2529-2540.
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2021Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry, Oncotarget. 2021; 12:475-492.
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2020SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes., Neuron 2020 09; 107(6): 1141-1159.e7.
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2020An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency., Oncogene 2020 Sep; (): .
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2020Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells., Cell Rep 2020 09; 32(11): 108146.
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2020Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells, Immunity 2020 02; 52(2): 328-341.e5.
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2018SUMO safeguards somatic and pluripotent cell identities by enforcing distinct chromatin states, Cell Stem Cell. 2018 Nov 1;23(5):742-757.e8. doi: 10.1016/j.stem.2018.10.001.
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2018Early-onset liver cancer in South America associates with low hepatitis B virus DNA burden, Sci Rep 2018 Aug;8(1):12031.
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2017entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation, Elife 2017 12;6.
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2017Shigella entry unveals a calcium/calpain-dependent mechanism for inhibiting sumoylation, Elife. 2017 Dec 12;6. pii: e27444. doi: 10.7554/eLife.27444..
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2017Is Required for Positive Selection and Late-Stage Maturation of Thymocytes, J. Immunol. 2017 05;198(9):3461-3470.
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2017SUMO and the robustness of cancer, Nat. Rev. Cancer 2017 01;.
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2017Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes., J. Immunol. 2017 May 1;198(9):3461-3470. .
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2016Protein SUMOylation Is Required for Regulatory T Cell Expansion and Function, Cell Rep 2016 Jul;16(4):1055-66.
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2015Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing, Nat. Immunol. 2016 Feb;17(2):140-9.
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2015TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma, Mol. Cancer 2015;14(1):74.
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2014A peculiar mutation spectrum emerging from young peruvian patients with hepatocellular carcinoma, PLoS ONE 2014;9(12):e114912.
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2014Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit, Nat Commun 2014 Nov;5:5323.
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2014Sumoylation controls host anti-bacterial response to the gut invasive pathogen Shigella flexneri, EMBO Rep. 2014 Sep;15(9):965-72.
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2014Sumoylation of human argonaute 2 at lysine-402 regulates its stability, PLoS ONE 2014;9(7):e102957.
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2014Common polymorphic effectors of immunity against hepatitis B and C modulate susceptibility to infection and spontaneous clearance in a Moroccan population, Infect. Genet. Evol. 2014 Aug;26:1-7.
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2014Mutation spectrum of hepatocellular carcinoma from eastern-European patients betrays the impact of a complex exposome, J Expo Sci Environ Epidemiol 2015 May;25(3):256-63.
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2013Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation, Genome Res. 2013 Oct;23(10):1563-79.
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2013Somatic changes in primary liver cancer in Russia: a pilot study, Mutat. Res. 2013 Aug;755(2):90-9.
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2013Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation, Mol. Cell. Biol. 2013 Jun;33(11):2163-77.
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2013Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway, EMBO Rep. 2013 Apr;14(4):356-63.
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2012Insertion/deletion polymorphisms are convenient and reliable markers to assess chromosomal instability in human tumors, Int. J. Biol. Markers 2012 Jul-Sep;27(3):e232-40.
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2012Associations of genetic variants in the transcriptional coactivators EP300 and PCAF with hepatocellular carcinoma, Cancer Epidemiol 2012 Oct;36(5):e300-5.
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2012[A new player in PML-mediated cellular senescence: TBX2 gets into the loop], Med Sci (Paris) 2012 Mar;28(3):248-50.
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2012Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells, Nat. Cell Biol. 2012 Mar;14(3):266-75.
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2011Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence, EMBO J. 2012 Jan;31(1):95-109.
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2011p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2, J. Exp. Med. 2011 May;208(5):875-83.
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2011Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism, Proc. Natl. Acad. Sci. U.S.A. 2011 Mar;108(12):4858-63.
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2011First multicenter study for risk factors for hepatocellular carcinoma development in North Africa, World J Hepatol 2011 Jan;3(1):24-30.
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2010Sumoylation by Ubc9 regulates the stem cell compartment and structure and function of the intestinal epithelium in mice, Gastroenterology 2011 Jan;140(1):286-96.
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2010Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis, PLoS Pathog. 2010 May;6(5):e1000928.
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2010Reprogramming of miRNA networks in cancer and leukemia, Genome Res. 2010 May;20(5):589-99.
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2010Listeria monocytogenes impairs SUMOylation for efficient infection, Nature 2010 Apr;464(7292):1192-5.
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2010SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7, Hum. Mol. Genet. 2010 Jan;19(1):181-95.
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2009miR-221 overexpression contributes to liver tumorigenesis, Proc. Natl. Acad. Sci. U.S.A. 2010 Jan;107(1):264-9.
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2009PARP-1 transcriptional activity is regulated by sumoylation upon heat shock, EMBO J. 2009 Nov;28(22):3534-48.
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2009The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer, Genome Res. 2009 Mar;19(3):438-51.
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2009[A review of cellular senescence: friend or foe of tumorigenesis?], Med Sci (Paris) 2009 Feb;25(2):153-60.
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2008Chromosome instability in human hepatocellular carcinoma depends on p53 status and aflatoxin exposure, Mutat. Res. 2008 May;653(1-2):6-13.
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2008Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity, Mol. Cell. Biol. 2008 Apr;28(8):2771-81.
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2008Genotype determination in Moroccan hepatitis B chronic carriers, Infect. Genet. Evol. 2008 May;8(3):306-12.
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2007Genomic stability prevails in North-African hepatocellular carcinomas, Dig Liver Dis 2007 Jul;39(7):671-7.
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2007SUMO is growing senescent, Cell Cycle 2007 Mar;6(6):677-81.
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2007C-terminal modifications regulate MDM2 dissociation and nuclear export of p53, Nat. Cell Biol. 2007 Apr;9(4):428-35.
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2007An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity, Mol. Cell. Biol. 2007 Apr;27(7):2661-75.
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2007Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer, Cancer Res. 2007 Feb;67(3):901-10.
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2007Role of SUMO in the dynamics of telomere maintenance in fission yeast, Proc. Natl. Acad. Sci. U.S.A. 2007 Jan;104(3):893-8.
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2006Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus, Nat. Cell Biol. 2007 Jan;9(1):45-56.
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2006Mutation analysis of the 8p22 candidate tumor suppressor gene ATIP/MTUS1 in hepatocellular carcinoma, Mol. Cell. Endocrinol. 2006 Jun;252(1-2):207-15.
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2005The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice, Dev. Cell 2005 Dec;9(6):769-79.
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2005FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family, J. Biol. Chem. 2005 Nov;280(45):38035-46.
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2005Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein, Mol. Cell. Biol. 2005 Jul;25(14):6289-302.
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2004A universal primer set for PCR amplification of nuclear histone H4 genes from all animal species, Mol. Biol. Evol. 2005 Mar;22(3):582-8.
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2004HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF, Oncogene 2004 Nov;23(54):8777-84.
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2004Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance, EMBO J. 2004 Oct;23(19):3844-53.
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2003Loss of parental-specific methylation at the IGF2 locus in human hepatocellular carcinoma, J. Pathol. 2003 Nov;201(3):473-9.
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2003Protein inhibitor of activated signal transducer and activator of transcription 1 interacts with the N-terminal domain of mineralocorticoid receptor and represses its transcriptional activity: implication of small ubiquitin-related modifier 1 modification, Mol. Endocrinol. 2003 Dec;17(12):2529-42.
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2003Nuclear and unclear functions of SUMO, Nat. Rev. Mol. Cell Biol. 2003 Sep;4(9):690-9.
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2003Homozygous deletions scanning in tumor cell lines detects previously unsuspected loci, Int. J. Cancer 2003 Aug;106(2):216-23.
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2003Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis, Hepatology 2003 Apr;37(4):852-61.
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2003Mutation analysis of novel human liver-related putative tumor suppressor gene in hepatocellular carcinoma, World J. Gastroenterol. 2003 Jan;9(1):89-93.
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2002Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1alpha, EMBO Rep. 2002 Oct;3(10):975-81.
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2002Deconstructing PML-induced premature senescence, EMBO J. 2002 Jul;21(13):3358-69.
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2002The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase, EMBO J. 2002 Jun;21(11):2682-91.
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2002The nucleoporin RanBP2 has SUMO1 E3 ligase activity, Cell 2002 Jan;108(1):109-20.
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2001SUMO: of branched proteins and nuclear bodies, Oncogene 2001 Oct;20(49):7243-9.
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2001Chromosomal abnormalities in liver cell dysplasia detected by comparative genomic hybridisation, MP, Mol. Pathol. 2001 Aug;54(4):270-4.
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2001Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modification, Mol. Cell. Biol. 2001 May;21(10):3314-24.
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2001Regulation of Pax3 transcriptional activity by SUMO-1-modified PML, Oncogene 2001 Jan;20(1):1-9.
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2000Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients, Oncogene 2000 Aug;19(33):3733-8.
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2000Role of SUMO-1-modified PML in nuclear body formation, Blood 2000 May;95(9):2748-52.
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2000c-Jun and p53 activity is modulated by SUMO-1 modification, J. Biol. Chem. 2000 May;275(18):13321-9.
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2000Effect of TT virus infection on hepatocellular carcinoma development: results of a Euro-Asian survey, J. Infect. Dis. 2000 Mar;181(3):1138-42.
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2000Covalent modification of the transcriptional repressor tramtrack by the ubiquitin-related protein Smt3 in Drosophila flies, Mol. Cell. Biol. 2000 Feb;20(3):1072-82.
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1999Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas, Oncogene 1999 Nov;18(47):6583-8.
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1999Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption, J. Virol. 1999 Jun;73(6):5137-43.
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1999The PML nuclear bodies: actors or extras?, Current Opinion in Genetics and Development, 1999, 9 (3), pp.362-367. ⟨10.1016/s0959-437x(99)80054-9⟩.
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1999Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma, Oncogene 1999 May;18(20):3127-34.
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1998Trivalent antimonials induce degradation of the PML-RAR oncoprotein and reorganization of the promyelocytic leukemia nuclear bodies in acute promyelocytic leukemia NB4 cells, Blood 1998 Dec;92(11):4308-16.
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1998Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment, Proc. Natl. Acad. Sci. U.S.A. 1998 Jun;95(13):7316-21.
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1998Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein, Oncogene 1998 May;16(19):2549-56.
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1998Extensive analysis of duplicated-inverted hepatitis B virus integrations in human hepatocellular carcinoma, J. Gen. Virol. 1998 Mar;79 ( Pt 3):591-600.
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1998Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus, EMBO J. 1998 Jan;17(1):61-70.
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1997SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia, Proc. Natl. Acad. Sci. U.S.A. 1997 Aug;94(17):9028-33.
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1997Molecular cloning of a new interferon-induced PML nuclear body-associated protein, J. Biol. Chem. 1997 Aug;272(31):19457-63.
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1997Comprehensive allelotyping of human hepatocellular carcinoma, Oncogene 1997 Jun;14(24):2927-33.
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1997The acute promyelocytic leukemia PML-RAR alpha protein induces hepatic preneoplastic and neoplastic lesions in transgenic mice, Oncogene 1997 Apr;14(13):1547-54.
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1997Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization, Genes Chromosomes Cancer 1997 Jan;18(1):59-65.
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1996A t(3;8) chromosomal translocation associated with hepatitis B virus intergration involves the carboxypeptidase N locus, J. Virol. 1996 Oct;70(10):7280-4.
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1996A retrovirus carrying the promyelocyte-retinoic acid receptor PML-RARalpha fusion gene transforms haematopoietic progenitors in vitro and induces acute leukaemias, EMBO J. 1996 Jun;15(11):2707-16.
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1996Retroviral vectors for the transduction of the PML-RARalpha fusion product of acute promyelocytic leukemia, Exp. Hematol. 1996 Mar;24(4):544-51.
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1995Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies, J. Cell Biol. 1995 Oct;131(1):45-56.
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1995The acute promyelocytic leukaemia-associated PML gene is induced by interferon, Oncogene 1995 Sep;11(5):871-6.
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1995Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways, Proc. Natl. Acad. Sci. U.S.A. 1995 Aug;92(16):7401-5.
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1995PML nuclear bodies are general targets for inflammation and cell proliferation, Cancer Res. 1995 Apr;55(7):1590-7.
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1994The PML-RAR gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells, Oncogene 1994, 9, 545-551..
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1994Retinoic acid regulates aberrant nuclear localization of PML-RAR in acute promyelocytic leukaemia cells, Cell 1994, 76, 345-356..
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1993A hepatitis B virus pre-S-retinoic acid receptor beta chimera transforms erythrocytic progenitor cells in vitro, Proc. Natl. Acad. Sci. U.S.A. 1993 Jan;90(1):89-93.
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1992A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia, Blood 1992 Jun;79(12):3110-5.
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1990Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene, Nature 1990 Jan;343(6254):177-80.
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1989Differential expression and ligand regulation of the retinoic acid receptor alpha and beta genes, EMBO J. 1989 Feb;8(2):429-33.
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1988Assignment of the human hap retinoic acid receptor RAR beta gene to the p24 band of chromosome 3, Hum. Genet. 1988 Oct;80(2):189-90.
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1988Identification of a second human retinoic acid receptor, Nature 1988 Apr;332(6167):850-3.
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1987A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma, Nature 1987 Dec 17-23;330(6149):667-70.
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1984Specific hepatitis B virus integration in hepatocellular carcinoma DNA through a viral 11-base-pair direct repeat, Proc. Natl. Acad. Sci. U.S.A. 1984 Sep;81(17):5350-4.
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1983Characterization of integrated hepatitis B viral DNA cloned from a human hepatoma and the hepatoma-derived cell line PLC/PRF/5, Proc. Natl. Acad. Sci. U.S.A. 1983 May;80(9):2505-9.
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1982Presence and state of woodchuck hepatitis virus DNA in liver and serum of woodchucks: further analogies with human hepatitis B virus, Virology 1982 Aug;121(1):195-9.
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