• 2017
  Bryant JM, Regnault C, Scheidig-Benatar C, Baumgarten S, Guizetti J, Scherf A, CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum, mBio. 2017 8(4):e00729-17.
• 2015
  Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL, Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH), J. Med. Chem. 2015 Jul;58(14):5579-98.
• 2015
  MacPherson CR, Scherf A, Flexible guide-RNA design for CRISPR applications using Protospacer Workbench, Nat. Biotechnol. 2015 Aug;33(8):805-6.
• 2015
  Doerig C, Rayner JC, Scherf A, Tobin AB, Post-translational protein modifications in malaria parasites, Nat. Rev. Microbiol. 2015 Mar;13(3):160-72.
• 2014
  Malmquist NA, Sundriyal S, Caron J, Chen P, Witkowski B, Menard D, Suwanarusk R, Renia L, Nosten F, Jiménez-Díaz MB, Angulo-Barturen I, Santos Martínez M, Ferrer S, Sanz LM, Gamo FJ, Wittlin S, Duffy S, Avery VM, Ruecker A, Delves MJ, Sinden RE, Fuchter MJ, Scherf A, Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans, Antimicrob. Agents Chemother. 2015 Feb;59(2):950-9.
• 2014
  Religa AA, Ramesar J, Janse CJ, Scherf A, Waters AP, P. berghei telomerase subunit TERT is essential for parasite survival, PLoS ONE 2014;9(9):e108930.
• 2014
  Vembar SS, Scherf A, Siegel TN, Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression, Curr. Opin. Microbiol. 2014 Aug;20:153-61.
• 2014
  Zhang Q, Siegel TN, Martins RM, Wang F, Cao J, Gao Q, Cheng X, Jiang L, Hon CC, Scheidig-Benatar C, Sakamoto H, Turner L, Jensen AT, Claes A, Guizetti J, Malmquist NA, Scherf A, Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria, Nature 2014 Sep;513(7518):431-5.
• 2014
  Ghorbal M, Gorman M, Macpherson CR, Martins RM, Scherf A, Lopez-Rubio JJ, Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system, Nat. Biotechnol. 2014 Aug;32(8):819-21.
• 2014
  Siegel TN, Hon CC, Zhang Q, Lopez-Rubio JJ, Scheidig-Benatar C, Martins RM, Sismeiro O, Coppée JY, Scherf A, Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum, BMC Genomics 2014;15:150.
• 2014
  Dembélé L, Franetich JF, Lorthiois A, Gego A, Zeeman AM, Kocken CH, Le Grand R, Dereuddre-Bosquet N, van Gemert GJ, Sauerwein R, Vaillant JC, Hannoun L, Fuchter MJ, Diagana TT, Malmquist NA, Scherf A, Snounou G, Mazier D, Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures, Nat. Med. 2014 Mar;20(3):307-12.
• 2013
  Jiang L, Mu J, Zhang Q, Ni T, Srinivasan P, Rayavara K, Yang W, Turner L, Lavstsen T, Theander TG, Peng W, Wei G, Jing Q, Wakabayashi Y, Bansal A, Luo Y, Ribeiro JM, Scherf A, Aravind L, Zhu J, Zhao K, Miller LH, PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum, Nature 2013 Jul;499(7457):223-7.
• 2013
  Guizetti J, Martins RM, Guadagnini S, Claes A, Scherf A, Nuclear pores and perinuclear expression sites of var and ribosomal DNA genes correspond to physically distinct regions in Plasmodium falciparum, Eukaryotic Cell 2013 May;12(5):697-702.
• 2013
  Guizetti J, Scherf A, Silence, activate, poise and switch! Mechanisms of antigenic variation in Plasmodium falciparum, Cell. Microbiol. 2013 May;15(5):718-26.
• 2013
  Dastidar EG, Dzeyk K, Krijgsveld J, Malmquist NA, Doerig C, Scherf A, Lopez-Rubio JJ, Comprehensive histone phosphorylation analysis and identification of Pf14-3-3 protein as a histone H3 phosphorylation reader in malaria parasites, PLoS ONE 2013;8(1):e53179.
• 2013
  Mancio-Silva L, Lopez-Rubio JJ, Claes A, Scherf A, Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum, Nat Commun 2013;4:1530.
• 2013
  Mancio-Silva L, Scherf A, In situ fluorescence visualization of transcription sites and genomic Loci in blood stages of Plasmodium falciparum, Methods Mol. Biol. 2013;923:335-51.
• 2013
  Lopez-Rubio JJ, Siegel TN, Scherf A, Genome-wide chromatin immunoprecipitation-sequencing in Plasmodium, Methods Mol. Biol. 2013;923:321-33.
• 2012
  Ghorbal M, Scheidig-Benatar C, Bouizem S, Thomas C, Paisley G, Faltermeier C, Liu M, Scherf A, Lopez-Rubio JJ, Gopaul DN, Initial characterization of the Pf-Int recombinase from the malaria parasite Plasmodium falciparum, PLoS ONE 2012;7(10):e46507.
• 2012
  Malmquist NA, Moss TA, Mecheri S, Scherf A, Fuchter MJ, Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum, Proc. Natl. Acad. Sci. U.S.A. 2012 Oct;109(41):16708-13.
• 2012
  Dastidar EG, Dayer G, Holland ZM, Dorin-Semblat D, Claes A, Chêne A, Sharma A, Hamelin R, Moniatte M, Lopez-Rubio JJ, Scherf A, Doerig C, Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathway, BMC Biol. 2012;10:5.
• 2011
  Nacer A, Roux E, Pomel S, Scheidig-Benatar C, Sakamoto H, Lafont F, Scherf A, Mattei D, Clag9 is not essential for PfEMP1 surface expression in non-cytoadherent Plasmodium falciparum parasites with a chromosome 9 deletion, PLoS ONE 2011;6(12):e29039.
• 2011
  Chêne A, Vembar SS, Rivière L, Lopez-Rubio JJ, Claes A, Siegel TN, Sakamoto H, Scheidig-Benatar C, Hernandez-Rivas R, Scherf A, PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites, Nucleic Acids Res. 2012 Apr;40(7):3066-77.
• 2011
  Zhang Q, Huang Y, Zhang Y, Fang X, Claes A, Duchateau M, Namane A, Lopez-Rubio JJ, Pan W, Scherf A, A critical role of perinuclear filamentous actin in spatial repositioning and mutually exclusive expression of virulence genes in malaria parasites, Cell Host Microbe 2011 Nov;10(5):451-63.
• 2010
  Fernandez P, Petres S, Mécheri S, Gysin J, Scherf A, Strain-transcendent immune response to recombinant Var2CSA DBL5-ε domain block P. falciparum adhesion to placenta-derived BeWo cells under flow conditions, PLoS ONE 2010;5(9):e12558.
• 2010
  Nunes MC, Okada M, Scheidig-Benatar C, Cooke BM, Scherf A, Plasmodium falciparum FIKK kinase members target distinct components of the erythrocyte membrane, PLoS ONE 2010;5(7):e11747.
• 2009
  Lopez-Rubio JJ, Mancio-Silva L, Scherf A, Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites, Cell Host Microbe 2009 Feb;5(2):179-90.
• 2008
  Issar N, Ralph SA, Mancio-Silva L, Keeling C, Scherf A, Differential sub-nuclear localisation of repressive and activating histone methyl modifications in P. falciparum, Microbes Infect. 2009 Mar;11(3):403-7.
• 2008
  Fernandez P, Viebig NK, Dechavanne S, Lépolard C, Gysin J, Scherf A, Gamain B, Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites, Malar. J. 2008;7:170.
• 2008
  Scherf A, Rivière L, Lopez-Rubio JJ, SnapShot: var gene expression in the malaria parasite, Cell 2008 Jul;134(1):190.
• 2008
  Nunes MC, Sterkers Y, Gamain B, Scherf A, Investigation of host factors possibly enhancing the emergence of the chondroitin sulfate A-binding phenotype in Plasmodium falciparum, Microbes Infect. 2008 Jul;10(8):928-32.
• 2008
  Mancio-Silva L, Rojas-Meza AP, Vargas M, Scherf A, Hernandez-Rivas R, Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum, J. Cell. Sci. 2008 Jun;121(Pt 12):2046-53.
• 2008
  Issar N, Roux E, Mattei D, Scherf A, Identification of a novel post-translational modification in Plasmodium falciparum: protein sumoylation in different cellular compartments, Cell. Microbiol. 2008 Oct;10(10):1999-2011.
• 2008
  Scherf A, Lopez-Rubio JJ, Riviere L, Antigenic variation in Plasmodium falciparum, Annu. Rev. Microbiol. 2008;62:445-70.
• 2007
  Nunes MC, Goldring JP, Doerig C, Scherf A, A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell, Mol. Microbiol. 2007 Jan;63(2):391-403.
• 2007
  Lopez-Rubio JJ, Gontijo AM, Nunes MC, Issar N, Hernandez Rivas R, Scherf A, 5′ flanking region of var genes nucleate histone modification patterns linked to phenotypic inheritance of virulence traits in malaria parasites, Mol. Microbiol. 2007 Dec;66(6):1296-305.
• 2007
  Lopez-Rubio JJ, Riviere L, Scherf A, Shared epigenetic mechanisms control virulence factors in protozoan parasites, Curr. Opin. Microbiol. 2007 Dec;10(6):560-8.
• 2007
  Viebig NK, Levin E, Dechavanne S, Rogerson SJ, Gysin J, Smith JD, Scherf A, Gamain B, Disruption of var2csa gene impairs placental malaria associated adhesion phenotype, PLoS ONE 2007;2(9):e910.
• 2006
  Gamain B, Smith JD, Viebig NK, Gysin J, Scherf A, Pregnancy-associated malaria: parasite binding, natural immunity and vaccine development, Int. J. Parasitol. 2007 Mar;37(3-4):273-83.
• 2006
  Avril M, Gamain B, Lépolard C, Viaud N, Scherf A, Gysin J, Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies, Microbes Infect. 2006 Nov-Dec;8(14-15):2863-71.
• 2006
  Scherf A, A greedy promoter controls malarial var-iations, Cell 2006 Jan;124(2):251-3.
• 2005
  Viebig NK, Nunes MC, Scherf A, Gamain B, The human placental derived BeWo cell line: a useful model for selecting Plasmodium falciparum CSA-binding parasites, Exp. Parasitol. 2006 Feb;112(2):121-5.
• 2005
  Ralph SA, Bischoff E, Mattei D, Sismeiro O, Dillies MA, Guigon G, Coppee JY, David PH, Scherf A, Transcriptome analysis of antigenic variation in Plasmodium falciparum–var silencing is not dependent on antisense RNA, Genome Biol. 2005;6(11):R93.
• 2005
  Gratepanche S, Scherf A, BioMalPar–a collaborative network of excellence on basic malaria research, Acta Trop. 2005 Sep;95(3):256-9.
• 2005
  Viebig NK, Gamain B, Scheidig C, Lépolard C, Przyborski J, Lanzer M, Gysin J, Scherf A, A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A, EMBO Rep. 2005 Aug;6(8):775-81.
• 2005
  Ralph SA, Scherf A, The epigenetic control of antigenic variation in Plasmodium falciparum, Curr. Opin. Microbiol. 2005 Aug;8(4):434-40.
• 2005
  Freitas-Junior LH, Hernandez-Rivas R, Ralph SA, Montiel-Condado D, Ruvalcaba-Salazar OK, Rojas-Meza AP, Mâncio-Silva L, Leal-Silvestre RJ, Gontijo AM, Shorte S, Scherf A, Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites, Cell 2005 Apr;121(1):25-36.
• 2005
  Ralph SA, Scheidig-Benatar C, Scherf A, Antigenic variation in Plasmodium falciparum is associated with movement of var loci between subnuclear locations, Proc. Natl. Acad. Sci. U.S.A. 2005 Apr;102(15):5414-9.
• 2005
  Figueiredo LM, Rocha EP, Mancio-Silva L, Prevost C, Hernandez-Verdun D, Scherf A, The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus, Nucleic Acids Res. 2005;33(3):1111-22.
• 2005
  Gamain B, Trimnell AR, Scheidig C, Scherf A, Miller LH, Smith JD, Identification of multiple chondroitin sulfate A (CSA)-binding domains in the var2CSA gene transcribed in CSA-binding parasites, J. Infect. Dis. 2005 Mar;191(6):1010-3.
• 2002
  Figueiredo LM, Freitas-Junior LH, Bottius E, Olivo-Marin JC, Scherf A, A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation, EMBO J. 2002 Feb;21(4):815-24.