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Guides
  • 2022
    Mallet A, Bastin P, , Restriction of intraflagellar transport to some microtubule doublets: An opportunity for cilia diversification?, Bioessays 2022 May; (): e2200031.
  • 2021
    Hutchinson S, Foulon S, Crouzols A, Menafra R, Rotureau B, Griffiths AD, Bastin P, , The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands., PLoS Pathog 2021 Sep; 17(9): e1009904.
  • 2021
    Calvo-Álvarez E, Bonnefoy S, Salles A, Benson FE, McKean PG, Bastin P, Rotureau B, , Redistribution of FLAgellar Member 8 during the trypanosome life cycle: Consequences for cell fate prediction., Cell Microbiol 2021 Apr; (): e13347.
  • 2021
    Bílý T, Sheikh S, Mallet A, Bastin P, Pérez-Morga D, Lukeš J, Hashimi H, , Ultrastructural Changes of the Mitochondrion During the Life Cycle of Trypanosoma brucei., J Eukaryot Microbiol 2021 Feb; (): e12846.
  • 2021
    Atkins M, Týč J, Shafiq S, Ahmed M, Bertiaux E, De Castro Neto AL, Sunter J, Bastin P, Dean SD, Vaughan S, , CEP164C regulates flagellum length in stable flagella., J Cell Biol 2021 Jan; 220(1): .
  • 2020
    Bertiaux E, Mallet A, Rotureau B, Bastin P, , Intraflagellar transport during assembly of flagella of different length in Trypanosoma brucei isolated from tsetse flies., J Cell Sci 2020 Sep; 133(18): .
  • 2020
    Rosazza T, Lecoeur H, Blisnick T, Moya-Nilges M, Pescher P, Bastin P, Prina E, Späth GF, , Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages., J Cell Sci 2020 06; 134(5): .
  • 2020
    Lemos M, Mallet A, Bertiaux E, Imbert A, Rotureau B, Bastin P, , Timing and original features of flagellum assembly in trypanosomes during development in the tsetse fly., Parasit Vectors 2020 Apr; 13(1): 169.
  • 2020
    Bertiaux E, Bastin P, Dealing with several flagella in the same cell, Cell. Microbiol. 2020 Jan;:e13162.
  • 2019
    Mallet A, Bastin P, [Molecular motors and microtubules: which type of relationship?], Med Sci (Paris) 2019 Apr;35(4):302-304.
  • 2019
    Wachter S, Jung J, Shafiq S, Basquin J, Fort C, Bastin P, Lorentzen E, Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly, EMBO J. 2019 Apr;.
  • 2019
    Efstathiou A, Gaboriaud-Kolar N, Myrianthopoulos V, Vougogiannopoulou K, Subota I, Aicher S, Mikros E, Bastin P, Skaltsounis AL, Soteriadou K, Smirlis D, Indirubin analogues inhibit Glycogen Synthase Kinase 3 short and growth, Antimicrob. Agents Chemother. 2019 Mar;.
  • 2019
    Huet D, Blisnick T, Perrot S, Bastin P, IFT25 is required for the construction of the trypanosome flagellum, J. Cell. Sci. 2019 Feb;.
  • 2018
    Bertiaux E, Mallet A, Fort C, Blisnick T, Bonnefoy S, Jung J, Lemos M, Marco S, Vaughan S, Trépout S, Tinevez JY, Bastin P, , Bidirectional intraflagellar transport is restricted to two sets of microtubule doublets in the trypanosome flagellum., J Cell Biol 2018 12; 217(12): 4284-4297.
  • 2018
    Bertiaux E, Morga B, Blisnick T, Rotureau B, Bastin P, A Grow-and-Lock Model for the Control of Flagellum Length in Trypanosomes, Curr. Biol. 2018 ;28(23):3802-3814.
  • 2018
    Bonnefoy S, Watson CM, Kernohan KD, Lemos M, Hutchinson S, Poulter JA, Crinnion LA, Berry I, Simmonds J, Vasudevan P, O'Callaghan C, Hirst RA, Rutman A, Huang L, Hartley T, Grynspan D, Moya E, Li C, Carr IM, Bonthron DT, Leroux M, , Boycott KM, Bastin P, Sheridan EG, Biallelic Mutations in LRRC56, Encoding a Protein Associated with Intraflagellar Transport, Cause Mucociliary Clearance and Laterality Defects, Am. J. Hum. Genet. 2018 Nov;103(5):727-739.
  • 2017
    Trépout S, Tassin AM, Marco S, Bastin P, STEM tomography analysis of the trypanosome transition zone, J. Struct. Biol. 2018 202 (1):51-60.
  • 2017
    Vincensini L, Blisnick T, Bertiaux E, Hutchinson S, Georgikou C, Ooi CP, Bastin P, Flagellar incorporation of proteins follows at least two different routes in trypanosomes, Biol. Cell 2018 110(2):33-47.
  • 2017
    Trépout S, Bastin P, Marco S, Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography, J Vis Exp 2017 Mar;(121).
  • 2016
    Fort C, Bonnefoy S, Kohl L, Bastin P, Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length, J Cell Sci. 2016 Aug 1;129(15):3026-41. doi: 10.1242/jcs.188227. Epub 2016 Jun 24.
  • 2015
    Serricchio M, Schmid AW, Steinmann ME, Sigel E, Rauch M, Julkowska D, Bonnefoy S, Fort C, Bastin P, Bütikofer P, Flagellar membranes are rich in raft-forming phospholipids, Biol Open 2015 Aug;.
  • 2015
    Perrault I, Halbritter J, Porath JD, Gérard X, Braun DA, Gee HY, Fathy HM, Saunier S, Cormier-Daire V, Thomas S, Attié-Bitach T, Boddaert N, Taschner M, Schueler M, Lorentzen E, Lifton RP, Lawson JA, Garfa-Traore M, Otto EA, Bastin P, Caillaud C, Kaplan J, Rozet JM, Hildebrandt F, IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype, J. Med. Genet. 2015 Aug;.
  • 2015
    Ooi CP, Rotureau B, Gribaldo S, Georgikou C, Julkowska D, Blisnick T, Perrot S, Subota I, Bastin P, The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies, PLoS ONE 2015;10(7):e0133676.
  • 2015
    Trepout S, Messaoudi C, Perrot S, Bastin P, Marco S, Scanning transmission electron microscopy through-focal tilt-series on biological specimens, Micron 2015 May;77:9-15.
  • 2015
    Benmerah A, Durand B, Giles RH, Harris T, Kohl L, Laclef C, Meilhac SM, Mitchison HM, Pedersen LB, Roepman R, Swoboda P, Ueffing M, Bastin P, The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies, Cilia 2015;4:5.
  • 2015
    Santi-Rocca J, Chenouard N, Fort C, Lagache T, Olivo-Marin JC, Bastin P, Imaging intraflagellar transport in trypanosomes, Methods Cell Biol. 2015;127:487-508.
  • 2015
    Bastin P, Rotureau B, Social motility in African trypanosomes: fact or model?, Trends Parasitol. 2015 Feb;31(2):37-8.
  • 2014
    Obishakin E, Stijlemans B, Santi-Rocca J, Vandenberghe I, Devreese B, Muldermans S, Bastin P, Magez S, Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes, PLoS ONE 2014;9(12):e115893.
  • 2014
    Fort C, Bastin P, [Elongation of the axoneme and dynamics of intraflagellar transport], Med Sci (Paris) 2014 Nov;30(11):955-61.
  • 2014
    Blisnick T, Buisson J, Absalon S, Marie A, Cayet N, Bastin P, The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions, Mol. Biol. Cell 2014 Sep;25(17):2620-33.
  • 2014
    Yau WL, Pescher P, MacDonald A, Hem S, Zander D, Retzlaff S, Blisnick T, Rotureau B, Rosenqvist H, Wiese M, Bastin P, Clos J, Späth GF, The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status, Mol. Microbiol. 2014 Jul;93(1):80-97.
  • 2014
    Huet D, Blisnick T, Perrot S, Bastin P, The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport, Elife 2014;3:e02419.
  • 2014
    Subota I, Julkowska D, Vincensini L, Reeg N, Buisson J, Blisnick T, Huet D, Perrot S, Santi-Rocca J, Duchateau M, Hourdel V, Rousselle JC, Cayet N, Namane A, Chamot-Rooke J, Bastin P, Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics, Mol. Cell Proteomics 2014 Jul;13(7):1769-86.
  • 2014
    Fort C, Bastin P, Boarder control on the IFT train, Elife 2014;3:e02531.
  • 2013
    Morga B, Bastin P, Getting to the heart of intraflagellar transport using Trypanosoma and Chlamydomonas models: the strength is in their differences, Cilia 2013;2(1):16.
  • 2013
    Ooi CP, Bastin P, More than meets the eye: understanding Trypanosoma brucei morphology in the tsetse, Front Cell Infect Microbiol 2013;3:71.
  • 2013
    Rotureau B, Ooi CP, Huet D, Perrot S, Bastin P, Forward motility is essential for trypanosome infection in the tsetse fly, Cell. Microbiol. 2014 Mar;16(3):425-33.
  • 2013
    Rotureau B, Blisnick T, Subota I, Julkowska D, Cayet N, Perrot S, Bastin P, Flagellar adhesion in Trypanosoma brucei relies on interactions between different skeletal structures in the flagellum and cell body, J. Cell. Sci. 2014 Jan;127(Pt 1):204-15.
  • 2013
    Bhogaraju S, Cajanek L, Fort C, Blisnick T, Weber K, Taschner M, Mizuno N, Lamla S, Bastin P, Nigg EA, Lorentzen E, Molecular basis of tubulin transport within the cilium by IFT74 and IFT81, Science 2013 Aug;341(6149):1009-12.
  • 2012
    Foucher AL, Rachidi N, Gharbi S, Blisnick T, Bastin P, Pemberton IK, Späth GF, , Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani., Antimicrob Agents Chemother 2013 Mar; 57(3): 1252-61.
  • 2012
    Brasseur A, Rotureau B, Vermeersch M, Blisnick T, Salmon D, Bastin P, Pays E, Vanhamme L, Pérez-Morga D, Trypanosoma brucei FKBP12 differentially controls motility and cytokinesis in procyclic and bloodstream forms, Eukaryotic Cell 2013 Feb;12(2):168-81.
  • 2012
    Buisson J, Chenouard N, Lagache T, Blisnick T, Olivo-Marin JC, Bastin P, Intraflagellar transport proteins cycle between the flagellum and its base, J. Cell. Sci. 2013 Jan;126(Pt 1):327-38.
  • 2012
    Rotureau B, Subota I, Buisson J, Bastin P, A new asymmetric division contributes to the continuous production of infective trypanosomes in the tsetse fly, Development 2012 May;139(10):1842-50.
  • 2012
    DuBois KN, Alsford S, Holden JM, Buisson J, Swiderski M, Bart JM, Ratushny AV, Wan Y, Bastin P, Barry JD, Navarro M, Horn D, Aitchison JD, Rout MP, Field MC, NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions, PLoS Biol. 2012;10(3):e1001287.
  • 2011
    Subota I, Rotureau B, Blisnick T, Ngwabyt S, Durand-Dubief M, Engstler M, Bastin P, ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation, Mol. Biol. Cell 2011 Nov;22(22):4205-19.
  • 2011
    Pescher P, Blisnick T, Bastin P, Späth GF, Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation, Cell. Microbiol. 2011 Jul;13(7):978-91.
  • 2011
    Vincensini L, Blisnick T, Bastin P, [The importance of model organisms to study cilia and flagella biology], Biol Aujourdhui 2011;205(1):5-28.
  • 2011
    Vincensini L, Blisnick T, Bastin P, 1001 model organisms to study cilia and flagella, Biol. Cell 2011 Mar;103(3):109-30.
  • 2011
    Ghossoub R, Molla-Herman A, Bastin P, Benmerah A, The ciliary pocket: a once-forgotten membrane domain at the base of cilia, Biol. Cell 2011 Mar;103(3):131-44.
  • 2011
    Rotureau B, Subota I, Bastin P, Molecular bases of cytoskeleton plasticity during the Trypanosoma brucei parasite cycle, Cell. Microbiol. 2011 May;13(5):705-16.
  • 2010
    Yau WL, Blisnick T, Taly JF, Helmer-Citterich M, Schiene-Fischer C, Leclercq O, Li J, Schmidt-Arras D, Morales MA, Notredame C, Romo D, Bastin P, Späth GF, , Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability., PLoS Negl Trop Dis 2010 Jun; 4(6): e729.
  • 2010
    Bastin P, The peculiarities of flagella in parasitic protozoa, Curr. Opin. Microbiol. 2010 Aug;13(4):450-2.
  • 2010
    Molla-Herman A, Ghossoub R, Blisnick T, Meunier A, Serres C, Silbermann F, Emmerson C, Romeo K, Bourdoncle P, Schmitt A, Saunier S, Spassky N, Bastin P, Benmerah A, The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia, J. Cell. Sci. 2010 May;123(Pt 10):1785-95.
  • 2009
    Julkowska D, Bastin P, Tools for analyzing intraflagellar transport in trypanosomes, Methods Cell Biol. 2009;93:59-80.
  • 2009
    Duquesnoy P, Escudier E, Vincensini L, Freshour J, Bridoux AM, Coste A, Deschildre A, de Blic J, Legendre M, Montantin G, Tenreiro H, Vojtek AM, Loussert C, Clément A, Escalier D, Bastin P, Mitchell DR, Amselem S, Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia, Am. J. Hum. Genet. 2009 Dec;85(6):890-6.
  • 2009
    Demonchy R, Blisnick T, Deprez C, Toutirais G, Loussert C, Marande W, Grellier P, Bastin P, Kohl L, Kinesin 9 family members perform separate functions in the trypanosome flagellum, J. Cell Biol. 2009 Nov;187(5):615-22.
  • 2009
    Adhiambo C, Blisnick T, Toutirais G, Delannoy E, Bastin P, A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum, J. Cell. Sci. 2009 Mar;122(Pt 6):834-41.
  • 2009
    Rotureau B, Morales MA, Bastin P, Späth GF, The flagellum-mitogen-activated protein kinase connection in Trypanosomatids: a key sensory role in parasite signalling and development?, Cell. Microbiol. 2009 May;11(5):710-8.
  • 2008
    Absalon S, Blisnick T, Bonhivers M, Kohl L, Cayet N, Toutirais G, Buisson J, Robinson D, Bastin P, Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei, J. Cell. Sci. 2008 Nov;121(Pt 22):3704-16.
  • 2007
    Absalon S, Blisnick T, Kohl L, Toutirais G, Doré G, Julkowska D, Tavenet A, Bastin P, Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes, Mol. Biol. Cell 2008 Mar;19(3):929-44.
  • 2007
    Durand-Dubief M, Absalon S, Menzer L, Ngwabyt S, Ersfeld K, Bastin P, The Argonaute protein TbAGO1 contributes to large and mini-chromosome segregation and is required for control of RIME retroposons and RHS pseudogene-associated transcripts, Mol. Biochem. Parasitol. 2007 Dec;156(2):144-53.
  • 2007
    Absalon S, Kohl L, Branche C, Blisnick T, Toutirais G, Rusconi F, Cosson J, Bonhivers M, Robinson D, Bastin P, Basal body positioning is controlled by flagellum formation in Trypanosoma brucei, PLoS ONE 2007;2(5):e437.
  • 2006
    Branche C, Kohl L, Toutirais G, Buisson J, Cosson J, Bastin P, Conserved and specific functions of axoneme components in trypanosome motility, J. Cell. Sci. 2006 Aug;119(Pt 16):3443-55.
  • 2005
    Rusconi F, Durand-Dubief M, Bastin P, Functional complementation of RNA interference mutants in trypanosomes, BMC Biotechnol. 2005;5:6.
  • 2005
    Kohl L, Bastin P, The flagellum of trypanosomes, Int. Rev. Cytol. 2005;244:227-85.
  • 2003
    Durand-Dubief M, Bastin P, TbAGO1, an argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma brucei, BMC Biol. 2003;1:2.
  • 2003
    Kohl L, Robinson D, Bastin P, Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes, EMBO J. 2003 Oct;22(20):5336-46.
  • 2003
    Durand-Dubief M, Kohl L, Bastin P, Efficiency and specificity of RNA interference generated by intra- and intermolecular double stranded RNA in Trypanosoma brucei, Mol. Biochem. Parasitol. 2003 Jun;129(1):11-21.
  • 2003
    Kohl L, Robinson D, Bastin P, [The flagellum: from cell motility to morphogenesis], J. Soc. Biol. 2003;197(4):379-87.
  • 2001
    Bastin P, Galvani A, Sperling L, Genetic interference in protozoa, Res. Microbiol. 2001 Mar;152(2):123-9.
  • 2000
    Bastin P, Pullen TJ, Moreira-Leite FF, Gull K, Inside and outside of the trypanosome flagellum:a multifunctional organelle, Microbes Infect. 2000 Dec;2(15):1865-74.
  • 2000
    Bastin P, Ellis K, Kohl L, Gull K, Flagellum ontogeny in trypanosomes studied via an inherited and regulated RNA interference system, J. Cell. Sci. 2000 Sep;113 ( Pt 18):3321-8.
  • 1999
    Bastin P, MacRae TH, Francis SB, Matthews KR, Gull K, Flagellar morphogenesis: protein targeting and assembly in the paraflagellar rod of trypanosomes, Mol. Cell. Biol. 1999 Dec;19(12):8191-200.
  • 1999
    Bastin P, Pullen TJ, Sherwin T, Gull K, Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1, J. Cell. Sci. 1999 Nov;112 ( Pt 21):3769-77.
  • 1999
    Bastin P, Gull K, Assembly and function of complex flagellar structures illustrated by the paraflagellar rod of trypanosomes, Protist 1999 Aug;150(2):113-23.
  • 1998
    Bastin P, Sherwin T, Gull K, Paraflagellar rod is vital for trypanosome motility, Nature 1998 Feb;391(6667):548.
  • 1997
    Santrich C, Moore L, Sherwin T, Bastin P, Brokaw C, Gull K, LeBowitz JH, A motility function for the paraflagellar rod of Leishmania parasites revealed by PFR-2 gene knockouts, Mol. Biochem. Parasitol. 1997 Dec;90(1):95-109.
  • 1996
    Bastin P, Matthews KR, Gull K, The paraflagellar rod of kinetoplastida: solved and unsolved questions, Parasitol. Today (Regul. Ed.) 1996 Aug;12(8):302-7.
  • 1996
    Bastin P, Bagherzadeh Z, Matthews KR, Gull K, A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei, Mol. Biochem. Parasitol. 1996 May;77(2):235-9.
  • 1996
    Bastin P, Stephan A, Raper J, Saint-Remy JM, Opperdoes FR, Courtoy PJ, An M(r) 145,000 low-density lipoprotein (LDL)-binding protein is conserved throughout the Kinetoplastida order, Mol. Biochem. Parasitol. 1996 Feb-Mar;76(1-2):43-56.
  • 1995
    Coppens I, Bastin P, Levade T, Courtoy PJ, Activity, pharmacological inhibition and biological regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Trypanosoma brucei, Mol. Biochem. Parasitol. 1995 Jan;69(1):29-40.
  • 1994
    Bastin P, Coppens I, Saint-Remy JM, Baudhuin P, Opperdoes FR, Courtoy PJ, Identification of a specific epitope on the extracellular domain of the LDL-receptor of Trypanosoma brucei brucei, Mol. Biochem. Parasitol. 1994 Feb;63(2):193-202.
  • 1992
    Coppens I, Bastin P, Opperdoes FR, Baudhuin P, Courtoy PJ, Trypanosoma brucei brucei: antigenic stability of its LDL receptor and immunological cross-reactivity with the LDL receptor of the mammalian host, Exp. Parasitol. 1992 Feb;74(1):77-86.
  • 1991
    Coppens I, Bastin P, Courtoy PJ, Baudhuin P, Opperdoes FR, A rapid method purifies a glycoprotein of Mr 145,000 as the LDL receptor of Trypanosoma brucei brucei, Biochem. Biophys. Res. Commun. 1991 Jul;178(1):185-91.
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