• 2022
  Melanie Albrecht, Bianca Schaub, Stefanie Gilles, Jörg Köhl, Sabine Altrichter, David Voehringer, Edzard Spillner, Marc Ehlers, Friederike Jönsson, Karin Loser, Johannes U Mayer, Lennart M Rösner, Christian Möbs, Guido Heine, Wolfgang Pfützner, Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology, Eur J Immunol . 2022 Jun;52(6):851-855.
• 2022
  Krémer V, de Chaisemartin L, Jönsson F, , The role of neutrophils in antibody-driven autoimmune cytopenias., Int J Biochem Cell Biol 2022 Jun; 147(): 106231.
• 2022
  Canales-Herrerias P, Crickx E, Broketa M, Sokal A, Chenon G, Azzaoui I, Vandenberghe A, Perima A, Iannascoli B, Richard-Le Goff O, Castrillon C, Mottet G, Sterlin D, Robbins A, Michel M, England P, Millot GA, Eyer K, Baudry J, Mahevas M, Bruhns P, , High-affinity autoreactive plasma cells disseminate through multiple organs in patients with immune thrombocytopenic purpura., J Clin Invest 2022 May; (): .
• 2022
  Wang Y, Krémer V, Iannascoli B, Goff OR, Mancardi DA, Ramke L, de Chaisemartin L, Bruhns P, Jönsson F, , Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species., Eur J Immunol 2022 Feb; (): .
• 2021
  Marie-Belle El Mdawar, Blandine Maître, Stephanie Magnenat, Florian Tupin, Friederike Jonsson, Christian Gachet, Henri de la Salle, Béatrice Hechler, Platelet FcγRIIA-induced serotonin release exacerbates the severity of Transfusion-Related Acute Lung Injury in mice, Blood Adv. 2021 Sep 14;bloodadvances.2021004336.
• 2021
  Julien Stackowicz, Nicolas Gaudenzio, Nadine Serhan, Eva Conde, Ophélie Godon, Thomas Marichal, Philipp Starkl, Bianca Balbino, Axel Roers, Pierre Bruhns, Friederike Jönsson, Philippe Moguelet, Sophie Georgin-Lavialle, Lori Broderick, Hal M Hoffman, Stephen J Galli, Laurent L Reber , Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome, J Exp Med. 2021 Oct 4;218(10):e20201466. doi: 10.1084/jem.20201466.
• 2021
  Conde E, Bertrand R, Balbino B, Bonnefoy J, Stackowicz J, Caillot N, Colaone F, Hamdi S, Houmadi R, Loste A, Kamphuis JBJ, Huetz F, Guilleminault L, Gaudenzio N, Mougel A, Hardy D, Snouwaert JN, Koller BH, Serra V, Bruhns P, Grouard-Vogel G, Reber LL, , Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice., Nat Commun 2021 May; 12(1): 2574.
• 2021
  Godon O, Hechler B, Jönsson F, , The role of IgG subclasses and platelets in experimental anaphylaxis., J Allergy Clin Immunol 2021 Jan; (): .
• 2021
  Anna F, Goyard S, Lalanne AI, Nevo F, Gransagne M, Souque P, Louis D, Gillon V, Turbiez I, Bidard FC, Gobillion A, Savignoni A, Guillot-Delost M, Dejardin F, Dufour E, Petres S, Richard-Le Goff O, Choucha Z, Helynck O, Janin YL, Escriou N, Charneau P, Perez F, Rose T, Lantz O, , High seroprevalence but short-lived immune response to SARS-CoV-2 infection in Paris., Eur J Immunol 2021 01; 51(1): 180-190.
• 2020
  , High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics, Nat Biotechnol . 2020 Jun;38(6):715-721. doi: 10.1038/s41587-020-0466-7. Epub 2020 Mar 30..
• 2020
  Salz A, Gurniak C, Jönsson F, Witke W., Cofilin1-driven Actin Dynamics Controls Migration of Thymocytes and Is Essential for Positive Selection in the Thymus, J Cell Sci. 2020 Mar 6;133(5):jcs238048..
• 2020
  Sterlin D, Fadlallah J, Adams O, Fieschi C, Parizot C, Dorgham K, Rajkumar A, Autaa G, El-Kafsi H, Charuel JL, Juste C, Jönsson F, Candela T, Wardemann H, Aubry A, Capito C, Brisson H, Tresallet C, Cummings RD, Larsen M, Yssel H, von Gunten S, Gorochov G, Human IgA binds a diverse array of commensal bacteria, J. Exp. Med. 2020 Mar;217(3).
• 2020
  Stackowicz J, Jönsson F, Reber LL., Mouse Models and Tools for the in vivo Study of Neutrophils., Front Immunol. 2020 Jan 21;10:3130..
• 2019
  Wang Y, Jönsson F., Expression, Role, and Regulation of Neutrophil Fcγ Receptors., Front Immunol. 2019 Aug 27;10:1958. Review..
• 2019
  Friederike Jönsson*, Luc de Chaisemartin*, Vanessa Granger†, Aurélie Gouel-Chéron†, Caitlin M. Gillis, Qianqian Zhu, Fadia Dib, Pascale Nicaise-Roland, Christelle Ganneau, Maria Hurtado-Nedelec, Catherine Paugam-Burtz, Skander Necib, Hawa Keita-Meyer, Matthieu Le Dorze, Bernard Cholley, Olivier Langeron, Laurent Jacob, Benoit Plaud, Marc Fischler, Caroline Sauvan, Marie-Thérèse Guinnepain, Philippe Montravers, Michel Aubier, Sylvie Bay, Catherine Neukirch, Florence Tubach‡, Dan Longrois‡, Sylvie Chollet-Martin‡,§ and Pierre Bruhns‡,§ , An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis, Sci Transl Med. 2019 Jul 10: Vol. 11, Issue 500, eaat1479 DOI: 10.1126/scitranslmed.aat1479 .
• 2018
  Anderson MC, Chaze T, Coïc YM, Injarabian L, Jonsson F, Lombion N, Selimoglu-Buet D, Souphron J, Ridley C, Vonaesch P, Baron B, Arena ET, Tinevez JY, Nigro G, Nothelfer K, Solary E, Lapierre V, Lazure T, Matondo M, Thornton D, Sansonetti PJ, Baleux F, Marteyn BS, , MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker., Cell Chem Biol 2018 04; 25(4): 483-493.e9.
• 2018
  Beutier H, Hechler B, Godon O, Wang Y, Gillis CM, de Chaisemartin L, Gouel-Chéron A, Magnenat S, Macdonald LE, Murphy AJ; NASA study group, Chollet-Martin S, Longrois D, Gachet C, Bruhns P, Jönsson F., Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis., Sci Immunol. 2018 Apr 13;3(22). .
• 2017
  Gouel-Chéron A, de Chaisemartin L, Jönsson F, Nicaise-Roland P, Granger V, Sabahov A, Guinnepain MT, Chollet-Martin S, Bruhns P, Neukirch C, Longrois D; NASA study group., Low end-tidal CO2 as a real-time severity marker of intra-anaesthetic acute hypersensitivity reactions., Br J Anaesth. 2017 Nov 1;119(5):908-917.
• 2017
  [Laurent L. Reber*, Caitlin M. Gillis*], Philipp Starkl, Friederike Jönsson, Riccardo Sibilano, Thomas Marichal, Nicolas Gaudenzio, Marion Bérard, Stephan Rogalla, Christopher H. Contag, [Pierre Bruhns$ and Stephen J. Galli$], Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide, J Exp Med, 2017; in press.
• 2016
  Gillis CM, Zenatti PP, Mancardi DA, Beutier H, Fiette L, Macdonald LE, Murphy AJ, Celli S, Bousso P, Jönsson F, Bruhns P., In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models., J Autoimmun. 2016 Oct 10. pii: S0896-8411(16)30183-4..
• 2016
  Gillis CM, Jönsson F, Mancardi DA, Tu N, Beutier H, Van Rooijen N, Macdonald LE, Murphy AJ, Bruhns P., Mechanisms of anaphylaxis in human low-affinity IgG receptor locus knock-in mice., J Allergy Clin Immunol. 2016 Aug 24..
• 2016
  Reitz M, Brunn ML, Rodewald HR, Feyerabend TB, Roers A, Dudeck A, Voehringer D, Jönsson F, Kühl AA, Breloer M., Mucosal mast cells are indispensable for the timely termination of Strongyloides ratti infection.fr, Mucosal Immunol. 2016 Jul 6..
• 2016
  Beutier H, Gillis CM, Iannascoli B, Godon O, England P, Sibilano R, Reber LL, Galli SJ, Cragg MS, Van Rooijen N, Mancardi DA, Bruhns P, Jönsson F, IgG subclasses determine pathways of anaphylaxis in mice, J. Allergy Clin. Immunol. 2017 01;139(1):269-280.e7.
• 2016
  Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J., Human IgG1 antibodies suppress angiogenesis in a target-independent manner, Signal Transduct Target Ther. 2016;1. pii: 15001. Epub 2016 Jan 28..
• 2015
  Bruhns P, Jönsson F., Mouse and human FcR effector functions., Immunol Rev. 2015 Nov;268(1):25-51..
• 2015
  Guenin-Macé L, Baron L, Chany AC, Tresse C, Saint-Auret S, Jönsson F, Le Chevalier F, Bruhns P, Bismuth G, Hidalgo-Lucas S, Bisson JF, Blanchard N, Demangel C, Shaping mycolactone for therapeutic use against inflammatory disorders, Sci Transl Med 2015 May;7(289):289ra85.
• 2014
  Domínguez-Soto A, de las Casas-Engel M, Bragado R, Medina-Echeverz J, Aragoneses-Fenoll L, Martín-Gayo E, van Rooijen N, Berraondo P, Toribio ML, Moro MA, Cuartero I, Castrillo A, Sancho D, Sánchez-Torres C, Bruhns P, Sánchez-Ramón S, Corbí AL, Intravenous immunoglobulin promotes antitumor responses by modulating macrophage polarization, J. Immunol. 2014 Nov;193(10):5181-9.
• 2014
  Turini M, Chames P, Bruhns P, Baty D, Kerfelec B, A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy, Oncotarget 2014 Jul;5(14):5304-19.
• 2014
  Ben Mkaddem S, Hayem G, Jönsson F, Rossato E, Boedec E, Boussetta T, El Benna J, Launay P, Goujon JM, Benhamou M, Bruhns P, Monteiro RC, Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis, J. Clin. Invest. 2014 Sep;124(9):3945-59.
• 2014
  Gillis C, Gouel-Chéron A, Jönsson F, Bruhns P, Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies, Front Immunol 2014;5:254.
• 2014
  Gurniak CB, Chevessier F, Jokwitz M, Jönsson F, Perlas E, Richter H, Matern G, Boyl PP, Chaponnier C, Fürst D, Schröder R, Witke W, Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance, Eur. J. Cell Biol. 2014 May-Jun;93(5-6):252-66.
• 2014
  Guilliams M, Bruhns P, Saeys Y, Hammad H, Lambrecht BN, The function of Fcγ receptors in dendritic cells and macrophages, Nat. Rev. Immunol. 2014 Feb;14(2):94-108.
• 2013
  Albanesi M, Mancardi DA, Jönsson F, Iannascoli B, Fiette L, Di Santo JP, Lowell CA, Bruhns P, Neutrophils mediate antibody-induced antitumor effects in mice, Blood 2013 Oct;122(18):3160-4.
• 2013
  Jönsson F, Mancardi DA, Albanesi M, Bruhns P, Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions, J. Leukoc. Biol. 2013 Oct;94(4):643-56.
• 2013
  Mancardi DA, Albanesi M, Jönsson F, Iannascoli B, Van Rooijen N, Kang X, England P, Daëron M, Bruhns P, The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy, Blood 2013 Feb;121(9):1563-73.
• 2012
  Montaudouin C, Anson M, Hao Y, Duncker SV, Fernandez T, Gaudin E, Ehrenstein M, Kerr WG, Colle JH, Bruhns P, Daëron M, Freitas AA, Quorum sensing contributes to activated IgM-secreting B cell homeostasis, J. Immunol. 2013 Jan;190(1):106-14.
• 2012
  Albanesi M, Mancardi DA, Macdonald LE, Iannascoli B, Zitvogel L, Murphy AJ, Daëron M, Leusen JH, Bruhns P, Cutting edge: FcγRIII (CD16) and FcγRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma, J. Immunol. 2012 Dec;189(12):5513-7.
• 2012
  Ordoñez-Rueda D, Jönsson F, Mancardi DA, Zhao W, Malzac A, Liang Y, Bertosio E, Grenot P, Blanquet V, Sabrautzki S, de Angelis MH, Méresse S, Duprez E, Bruhns P, Malissen B, Malissen M, A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia, Eur. J. Immunol. 2012 Sep;42(9):2395-408.
• 2012
  Hoffmann E, Kotsias F, Visentin G, Bruhns P, Savina A, Amigorena S, Autonomous phagosomal degradation and antigen presentation in dendritic cells, Proc. Natl. Acad. Sci. U.S.A. 2012 Sep;109(36):14556-61.
• 2012
  Cassard L, Jönsson F, Arnaud S, Daëron M, Fcγ receptors inhibit mouse and human basophil activation, J. Immunol. 2012 Sep;189(6):2995-3006.
• 2012
  Fang Y, Larsson L, Bruhns P, Xiang Z, Apoptosis of mouse mast cells is reciprocally regulated by the IgG receptors FcγRIIB and FcγRIIIA, Allergy 2012 Oct;67(10):1233-40.
• 2012
  Jönsson F, Gurniak CB, Fleischer B, Kirfel G, Witke W, Immunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADF, PLoS ONE 2012;7(4):e36034.
• 2012
  Bruhns P, Properties of mouse and human IgG receptors and their contribution to disease models, Blood 2012 Jun;119(24):5640-9.
• 2012
  Jönsson F, Daëron M, Mast cells and company, Front Immunol 2012;3:16.
• 2011
  Jönsson F, Mancardi DA, Zhao W, Kita Y, Iannascoli B, Khun H, van Rooijen N, Shimizu T, Schwartz LB, Daëron M, Bruhns P, Human FcγRIIA induces anaphylactic and allergic reactions, Blood 2012 Mar;119(11):2533-44.
• 2011
  Jönsson F, Mancardi DA, Daëron M, Bruhns P, [An unexpected role for neutrophils in anaphylaxis], Med Sci (Paris) 2011 Oct;27(10):823-5.
• 2011
  Schiffer C, Lalanne AI, Cassard L, Mancardi DA, Malbec O, Bruhns P, Dif F, Daëron M, A strain of Lactobacillus casei inhibits the effector phase of immune inflammation, J. Immunol. 2011 Sep;187(5):2646-55.
• 2011
  Jönsson F, Mancardi DA, Kita Y, Karasuyama H, Iannascoli B, Van Rooijen N, Shimizu T, Daëron M, Bruhns P, Mouse and human neutrophils induce anaphylaxis, J. Clin. Invest. 2011 Apr;121(4):1484-96.
• 2011
  Araujo LM, Chauvineau A, Zhu R, Diem S, Bourgeois EA, Levescot A, Huerre M, Gombert JM, Bayry J, Daëron M, Bruhns P, Kaveri SV, Herbelin A, Cutting edge: intravenous Ig inhibits invariant NKT cell-mediated allergic airway inflammation through FcγRIIIA-dependent mechanisms, J. Immunol. 2011 Mar;186(6):3289-93.
• 2011
  Mancardi DA, Jönsson F, Iannascoli B, Khun H, Van Rooijen N, Huerre M, Daëron M, Bruhns P, Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis, J. Immunol. 2011 Feb;186(4):1899-903.
• 2010
  Lochner M, Ohnmacht C, Presley L, Bruhns P, Si-Tahar M, Sawa S, Eberl G, Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells, J. Exp. Med. 2011 Jan;208(1):125-34.
• 2010
  Syam S, Mero P, Pham T, McIntosh CA, Bruhns P, Booth JW, Differential recruitment of activating and inhibitory Fc gamma RII during phagocytosis, J. Immunol. 2010 Mar;184(6):2966-73.
• 2009
  Hudrisier D, Clemenceau B, Balor S, Daubeuf S, Magdeleine E, Daëron M, Bruhns P, Vié H, Ligand binding but undetected functional response of FcR after their capture by T cells via trogocytosis, J. Immunol. 2009 Nov;183(10):6102-13.
• 2009
  Meknache N, Jönsson F, Laurent J, Guinnepain MT, Daëron M, Human basophils express the glycosylphosphatidylinositol-anchored low-affinity IgG receptor FcgammaRIIIB (CD16B), J. Immunol. 2009 Feb;182(4):2542-50.
• 2008
  Bruhns P, Iannascoli B, England P, Mancardi DA, Fernandez N, Jorieux S, Daëron M, Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses, Blood 2009 Apr;113(16):3716-25.
• 2008
  Mancardi DA, Iannascoli B, Hoos S, England P, Daëron M, Bruhns P, FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation, J. Clin. Invest. 2008 Nov;118(11):3738-50.
• 2005
  Isnardi I, Bruhns P, Bismuth G, Fridman WH, Daëron M, The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcgammaRIIB and is mandatory for negative regulation of B cell activation, Immunol. Lett. 2006 Apr;104(1-2):156-65.
• 2005
  Bruhns P, Frémont S, Daëron M, Regulation of allergy by Fc receptors, Curr. Opin. Immunol. 2005 Dec;17(6):662-9.
• 2005
  Nimmerjahn F, Bruhns P, Horiuchi K, Ravetch JV, FcgammaRIV: a novel FcR with distinct IgG subclass specificity, Immunity 2005 Jul;23(1):41-51.
• 2005
  Olsson M, Bruhns P, Frazier WA, Ravetch JV, Oldenborg PA, Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia, Blood 2005 May;105(9):3577-82.
• 2004
  Isnardi I, Lesourne R, Bruhns P, Fridman WH, Cambier JC, Daëron M, Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap, J. Biol. Chem. 2004 Dec;279(50):51931-8.
• 2003
  Turhan A, Jenab P, Bruhns P, Ravetch JV, Coller BS, Frenette PS, Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes, Blood 2004 Mar;103(6):2397-400.
• 2003
  Bruhns P, Samuelsson A, Pollard JW, Ravetch JV, Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease, Immunity 2003 Apr;18(4):573-81.