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Guides
  • 2022
    Freyer L, Lallemand Y, Dardenne P, Sommer A, Biton A, Gomez Perdiguero E, , Erythro-myeloid progenitor origin of Hofbauer cells in the early mouse placenta., Development 2022 Apr; 149(8): .
  • 2021
    Iturri L, Freyer L, Biton A, Dardenne P, Lallemand Y, Gomez Perdiguero E, , Megakaryocyte production is sustained by direct differentiation from erythromyeloid progenitors in the yolk sac until midgestation., Immunity 2021 May; (): .
  • 2021
    Soares-da-Silva F, Freyer L, Elsaid R, Burlen-Defranoux O, Iturri L, Sismeiro O, Pinto-do-Ó P, Gomez-Perdiguero E, Cumano A, , Yolk sac, but not hematopoietic stem cell-derived progenitors, sustain erythropoiesis throughout murine embryonic life., J Exp Med 2021 04; 218(4): .
  • 2020
    Lacerda Mariano L, Rousseau M, Varet H, Legendre R, Gentek R, Saenz Coronilla J, Bajenoff M, Gomez Perdiguero E, Ingersoll MA, , Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder., Sci Adv 2020 Nov; 6(48): .
  • 2020
    Weinberger T, Esfandyari D, Messerer D, Percin G, Schleifer C, Thaler R, Liu L, Stremmel C, Schneider V, Vagnozzi RJ, Schwanenkamp J, Fischer M, Busch K, Klapproth K, Ishikawa-Ankerhold H, Klösges L, Titova A, Molkentin JD, Kobayashi Y, Engelhardt S, Massberg S, Waskow C, Perdiguero EG, Schulz C, , Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation., Nat Commun 2020 09; 11(1): 4549.
  • 2020
    Elsaid R, Meunier S, Burlen-Defranoux O, Soares-da-Silva F, Perchet T, Iturri L, Freyer L, Vieira P, Pereira P, Golub R, Bandeira A, Gomez Perdiguero E, Cumano A, , A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner., Blood 2021 Feb 25; 137(8): 1024-1036.
  • 2018
    Yang S, Pascual-Guiral S, Ponce R, Giménez-Llort L, Baltrons MA, Arancio O, Palacio JR, Clos VM, Yuste VJ, Bayascas JR, Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides, Front Aging Neurosci 2017;9:435.
  • 2017
    Freyer L, Hsu CW, Nowotschin S, Pauli A, Ishida J, Kuba K, Fukamizu A, Schier AF, Hoodless PA, Dickinson ME, Hadjantonakis AK, , Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives., Cell Rep 2017 Aug; 20(9): 2116-2130.
  • 2017
    Iturri L, Saenz Coronilla J, Lallemand Y, Gomez Perdiguero E, Identification Of Erythromyeloid Progenitors And Their Progeny In The Mouse Embryo By Flow Cytometry, J Vis Exp 2017 Jul;(125).
  • 2017
    Kasaai B, Caolo V, Peacock HM, Lehoux S, Gomez-Perdiguero E, Luttun A, Jones EA, , Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling., Sci Rep 2017 03; 7(): 43817.
  • 2016
    Menezes S, Melandri D, Anselmi G, Perchet T, Loschko J, Dubrot J, Patel R, Gautier EL, Hugues S, Longhi MP, Henry JY, Quezada SA, Lauvau G, Lennon-Duménil AM, Gutiérrez-Martínez E, Bessis A, Gomez-Perdiguero E, Jacome-Galarza CE, Garner H, Geissmann F, Golub R, Nussenzweig MC, Guermonprez P, The Heterogeneity of Ly6C(hi) Monocytes Controls Their Differentiation into iNOS(+) Macrophages or Monocyte-Derived Dendritic Cells, Immunity 2016 Dec;45(6):1205-1218.
  • 2016
    Gomez Perdiguero E, Liabotis-Fontugne A, Durand M, Faye C, Ricard-Blum S, Simonutti M, Augustin S, Robb BM, Paques M, Valenzuela DM, Murphy AJ, Yancopoulos GD, Thurston G, Galaup A, Monnot C, Germain S, ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2, J. Pathol. 2016 Aug;.
  • 2016
    Kierdorf K, Prinz M, Geissmann F, Gomez Perdiguero E, Development and function of tissue resident macrophages in mice, Semin. Immunol. 2015 Dec;27(6):369-78.
  • 2016
    Elisa Gomez Perdiguero and Frederic Geissmann, The development and maintenance of resident macrophages, Nature Immunology 17, 2–8 (2016).
  • 2015
    Perdiguero EG, Geissmann F, The development and maintenance of resident macrophages, Nat. Immunol. 2015 Dec;17(1):2-8.
  • 2015
    Gomez Perdiguero E, Klapproth K, Schulz C, Busch K, de Bruijn M, Rodewald HR, Geissmann F, The Origin of Tissue-Resident Macrophages: When an Erythro-myeloid Progenitor Is an Erythro-myeloid Progenitor, Immunity 2015 Dec;43(6):1023-4.
  • 2015
    Freyer L, Schröter C, Saiz N, Schrode N, Nowotschin S, Martinez-Arias A, Hadjantonakis AK, A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice, BMC Dev. Biol. 2015 Oct;15:38.
  • 2014
    Gomez Perdiguero E, Klapproth K, Schulz C, Busch K, Azzoni E, Crozet L, Garner H, Trouillet C, de Bruijn MF, Geissmann F, Rodewald HR, Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors, Nature 2015 Feb;518(7540):547-51.
  • 2014
    Bain CC, Bravo-Blas A, Scott CL, Gomez Perdiguero E, Geissmann F, Henri S, Malissen B, Osborne LC, Artis D, Mowat AM, Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice, Nat. Immunol. 2014 Oct;15(10):929-37.
  • 2014
    Gomez Perdiguero E, Geissmann F, Cancer immunology. Identifying the infiltrators, Science 2014 May;344(6186):801-2.
  • 2013
    Gomez Perdiguero E, Geissmann F, Myb-independent macrophages: a family of cells that develops with their tissue of residence and is involved in its homeostasis, Cold Spring Harb. Symp. Quant. Biol. 2013;78:91-100.
  • 2013
    Böiers C, Carrelha J, Lutteropp M, Luc S, Green JC, Azzoni E, Woll PS, Mead AJ, Hultquist A, Swiers G, Perdiguero EG, Macaulay IC, Melchiori L, Luis TC, Kharazi S, Bouriez-Jones T, Deng Q, Pontén A, Atkinson D, Jensen CT, Sitnicka E, Geissmann F, Godin I, Sandberg R, de Bruijn MF, Jacobsen SE, Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells, Cell Stem Cell 2013 Nov;13(5):535-48.
  • 2013
    Freyer L, Nowotschin S, Pirity MK, Baldini A, Morrow BE, Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice, BMC Dev. Biol. 2013 Aug;13:33.
  • 2013
    Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M, Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways, Nat. Neurosci. 2013 Mar;16(3):273-80.
  • 2012
    Gomez Perdiguero E, Schulz C, Geissmann F, Development and homeostasis of “resident” myeloid cells: the case of the microglia, Glia 2013 Jan;61(1):112-20.
  • 2012
    Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F, A lineage of myeloid cells independent of Myb and hematopoietic stem cells, Science 2012 Apr;336(6077):86-90.
  • 2011
    Freyer L, Aggarwal V, Morrow BE, Dual embryonic origin of the mammalian otic vesicle forming the inner ear, Development 2011 Dec;138(24):5403-14.
  • 2011
    Galaup A, Gomez E, Souktani R, Durand M, Cazes A, Monnot C, Teillon J, Le Jan S, Bouleti C, Briois G, Philippe J, Pons S, Martin V, Assaly R, Bonnin P, Ratajczak P, Janin A, Thurston G, Valenzuela DM, Murphy AJ, Yancopoulos GD, Tissier R, Berdeaux A, Ghaleh B, Germain S, Protection against myocardial infarction and no-reflow through preservation of vascular integrity by angiopoietin-like 4, Circulation 2012 Jan;125(1):140-9.
  • 2011
    Perdiguero EG, Galaup A, Durand M, Teillon J, Philippe J, Valenzuela DM, Murphy AJ, Yancopoulos GD, Thurston G, Germain S, Alteration of developmental and pathological retinal angiogenesis in angptl4-deficient mice, J. Biol. Chem. 2011 Oct;286(42):36841-51.
  • 2011
    Guo X, Freyer L, Morrow B, Zheng D, Characterization of the past and current duplication activities in the human 22q11.2 region, BMC Genomics 2011 Jan;12:71.
  • 2011
    Todorovic V, Finnegan E, Freyer L, Zilberberg L, Ota M, Rifkin DB, Long form of latent TGF-β binding protein 1 (Ltbp1L) regulates cardiac valve development, Dev. Dyn. 2011 Jan;240(1):176-87.
  • 2010
    Freyer L, Morrow BE, Canonical Wnt signaling modulates Tbx1, Eya1, and Six1 expression, restricting neurogenesis in the otic vesicle, Dev. Dyn. 2010 Jun;239(6):1708-22.
  • 2010
    Aggarwal VS, Carpenter C, Freyer L, Liao J, Petti M, Morrow BE, Mesodermal Tbx1 is required for patterning the proximal mandible in mice, Dev. Biol. 2010 Aug;344(2):669-81.
  • 2008
    Bréchot N, Gomez E, Bignon M, Khallou-Laschet J, Dussiot M, Cazes A, Alanio-Bréchot C, Durand M, Philippe J, Silvestre JS, Van Rooijen N, Corvol P, Nicoletti A, Chazaud B, Germain S, Modulation of macrophage activation state protects tissue from necrosis during critical limb ischemia in thrombospondin-1-deficient mice, PLoS ONE 2008;3(12):e3950.
  • 2007
    Todorovic V, Frendewey D, Gutstein DE, Chen Y, Freyer L, Finnegan E, Liu F, Murphy A, Valenzuela D, Yancopoulos G, Rifkin DB, Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling, Development 2007 Oct;134(20):3723-32.
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