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Regulatory roles of signaling Nucleotides
Undine Mechold (PI)
Other research projects are aimed at exploring the regulatory role of different nucleotides such ppGpp and pppGpp that are both thought to act as second messengers in many complex cellular responses to nutritional […]
2017ExoY, an actin-activated nucleotidyl cyclase toxin from P. aeruginosa: A minireview, Toxicon 2018 Jul;149:65-71.
2016Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins, Nat Commun 2016 Dec;7:13582.
2015Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa, Proc. Natl. Acad. Sci. U.S.A. 2015 Aug;.
2014Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis, PLoS ONE 2014;9(1):e86096.
2013Differential regulation by ppGpp versus pppGpp in Escherichia coli, Nucleic Acids Res. 2013 Jul;41(12):6175-89.
20123′-5′ phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo, Biochem. J. 2012 Apr;443(2):485-90.
2012Identification of a novel nanoRNase in Bartonella, Microbiology (Reading, Engl.) 2012 Apr;158(Pt 4):886-95.
2011Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae, RNA 2012 Jan;18(1):155-65.
2009Analysis of interaction partners of H4 histone by a new proteomics approach, Proteomics 2009 Nov;9(21):4934-43.
2009Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis, Nucleic Acids Res. 2009 Aug;37(15):5114-25.
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