• 2023
  Magda Teixeira Nunes, Pascal Retailleau, Dorothée Raoux-Barbot, Martine Comisso, Anani Amegan Missinou, Christophe Velours, Stéphane Plancqueel, Daniel Ladant, Undine Mechold, Louis Renault, Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin, PLoS Pathogens, 2023, 19 (9), pp.e1011654. ⟨10.1371/journal.ppat.1011654⟩.
• 2021
  Belyy A, Merino F, Mechold U, Raunser S, , Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens., Nat Commun 2021 11; 12(1): 6628.
• 2018
  Raoux-Barbot D, Belyy A, Worpenberg L, Montluc S, Deville C, Henriot V, Velours C, Ladant D, Renault L, Mechold U, Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin, PLoS ONE 2018;13(11):e0206133.
• 2018
  Belyy A, Santecchia I, Renault L, Bourigault B, Ladant D, Mechold U, The extreme C terminus of the effector ExoY is crucial for binding to its eukaryotic activator, F-actin, J. Biol. Chem. 2018 12;293(51):19785-19796.
• 2017
  Belyy A, Mechold U, Renault L, Ladant D, ExoY, an actin-activated nucleotidyl cyclase toxin from P. aeruginosa: A minireview, Toxicon 2018 Jul;149:65-71.
• 2016
  Belyy A*, Raoux-Barbot D*, Saveanu C*, Namane A, Ogryzko V, Worpenberg L, David V, Henriot V, Fellous S, Merrifield C, Assayag E, Ladant D, Renault L, Mechold U, Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins, Nat Commun 2016 Dec;7:13582.
• 2015
  Cohen D, Mechold U, Nevenzal H, Yarmiyhu Y, Randall TE, Bay DC, Rich JD, Parsek MR, Kaever V, Harrison JJ, Banin E, Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa, Proc. Natl. Acad. Sci. U.S.A. 2015 Aug;.
• 2014
  Manikandan K, Sabareesh V, Singh N, Saigal K, Mechold U, Sinha KM, Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis, PLoS ONE 2014;9(1):e86096.
• 2013
  Mechold U, Potrykus K, Murphy H, Murakami KS, Cashel M, Differential regulation by ppGpp versus pppGpp in Escherichia coli, Nucleic Acids Res. 2013 Jul;41(12):6175-89.
• 2012
  Toledano E, Ogryzko V, Danchin A, Ladant D, Mechold U, 3′-5′ phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo, Biochem. J. 2012 Apr;443(2):485-90.
• 2012
  Liu MF, Cescau S, Mechold U, Wang J, Cohen D, Danchin A, Boulouis HJ, Biville F, Identification of a novel nanoRNase in Bartonella, Microbiology (Reading, Engl.) 2012 Apr;158(Pt 4):886-95.
• 2011
  Postic G, Danchin A, Mechold U, Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae, RNA 2012 Jan;18(1):155-65.
• 2009
  Saade E, Mechold U, Kulyyassov A, Vertut D, Lipinski M, Ogryzko V, Analysis of interaction partners of H4 histone by a new proteomics approach, Proteomics 2009 Nov;9(21):4934-43.
• 2009
  Fang M, Zeisberg WM, Condon C, Ogryzko V, Danchin A, Mechold U, Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis, Nucleic Acids Res. 2009 Aug;37(15):5114-25.
• 2008
  Shoaib M, Baconnais S, Mechold U, Le Cam E, Lipinski M, Ogryzko V, Multiple displacement amplification for complex mixtures of DNA fragments, BMC Genomics 2008;9:415.
• 2007
  Mechold U, Fang G, Ngo S, Ogryzko V, Danchin A, YtqI from Bacillus subtilis has both oligoribonuclease and pAp-phosphatase activity, Nucleic Acids Res. 2007;35(13):4552-61.
• 2006
  Viens A, Mechold U, Brouillard F, Gilbert C, Leclerc P, Ogryzko V, Analysis of human histone H2AZ deposition in vivo argues against its direct role in epigenetic templating mechanisms, Mol. Cell. Biol. 2006 Jul;26(14):5325-35.
• 2006
  Mechold U, Ogryzko V, Ngo S, Danchin A, Oligoribonuclease is a common downstream target of lithium-induced pAp accumulation in Escherichia coli and human cells, Nucleic Acids Res. 2006;34(8):2364-73.
• 2005
  Mechold U, Gilbert C, Ogryzko V, Codon optimization of the BirA enzyme gene leads to higher expression and an improved efficiency of biotinylation of target proteins in mammalian cells, J. Biotechnol. 2005 Mar;116(3):245-9.
• 2004
  Hogg T, Mechold U, Malke H, Cashel M, Hilgenfeld R, Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response [corrected], Cell 2004 Apr;117(1):57-68.
• 2004
  Viens A, Mechold U, Lehrmann H, Harel-Bellan A, Ogryzko V, Use of protein biotinylation in vivo for chromatin immunoprecipitation, Anal. Biochem. 2004 Feb;325(1):68-76.
• 2003
  Givens RM, Lin MH, Taylor DJ, Mechold U, Berry JO, Hernandez VJ, Inducible expression, enzymatic activity, and origin of higher plant homologues of bacterial RelA/SpoT stress proteins in Nicotiana tabacum, J. Biol. Chem. 2004 Feb;279(9):7495-504.
• 2002
  Mechold U, Murphy H, Brown L, Cashel M, Intramolecular regulation of the opposing (p)ppGpp catalytic activities of Rel(Seq), the Rel/Spo enzyme from Streptococcus equisimilis, J. Bacteriol. 2002 Jun;184(11):2878-88.
• 1998
  Wehmeier L, Schäfer A, Burkovski A, Krämer R, Mechold U, Malke H, Pühler A, Kalinowski J, The role of the Corynebacterium glutamicum rel gene in (p)ppGpp metabolism, Microbiology (Reading, Engl.) 1998 Jul;144 ( Pt 7):1853-62.
• 1997
  Mechold U, Malke H, Characterization of the stringent and relaxed responses of Streptococcus equisimilis, J. Bacteriol. 1997 Apr;179(8):2658-67.
• 1997
  Steiner K, Mechold U, Malke H, Elicitation of high (p)ppGpp levels in Streptococcus equisimilis without imposing nutritional deprivation, Adv. Exp. Med. Biol. 1997;418:991-3.
• 1996
  Mechold U, Cashel M, Steiner K, Gentry D, Malke H, Functional analysis of a relA/spoT gene homolog from Streptococcus equisimilis, J. Bacteriol. 1996 Mar;178(5):1401-11.
• 1995
  Malke H, Steiner K, Gase K, Mechold U, Ellinger T, The streptokinase gene: allelic variation, genomic environment and expression control, Dev. Biol. Stand. 1995;85:183-93.
• 1994
  Malke H, Mechold U, Gase K, Gerlach D, Inactivation of the streptokinase gene prevents Streptococcus equisimilis H46A from acquiring cell-associated plasmin activity in the presence of plasminogen, FEMS Microbiol. Lett. 1994 Feb;116(1):107-12.
• 1993
  Mechold U, Steiner K, Vettermann S, Malke H, Genetic organization of the streptokinase region of the Streptococcus equisimilis H46A chromosome, Mol. Gen. Genet. 1993 Oct;241(1-2):129-40.