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FUNPOLYVAC – Exploring fungal cell-wall polysaccharides for immunotherapies
Vishu Kumar Aimanianda Bopaiah (PI)
Interaction between host immunity and fungus starts with the fungal cell-wall (CW) contacting immune cell. Although this fungal CW is composed of a complex mixture of polysaccharides, their immunotherapeutic applications have been underexplored. The […]
2023The New GPI-Anchored Protein, SwgA, Is Involved in Nitrogen Metabolism in the Pathogenic Filamentous Fungus Aspergillus fumigatus., J Fungi (Basel) 2023 Feb; 9(2): .
2023Conidium Specific Polysaccharides in Aspergillus fumigatus., J Fungi (Basel) 2023 Jan; 9(2): .
2021Functional Genomic and Biochemical Analysis Reveals Pleiotropic Effect of Congo Red on Aspergillus fumigatus., mBio 2021 May; 12(3): .
2020Potential of chemically synthesized oligosaccharides to define the carbohydrate moieties of the fungal cell wall responsible for the human immune response, using Aspergillus fumigatus galactomannan as a model, mSphere 2020 01; 5(1): .
2018Novel mouse monoclonal antibodies specifically recognize Aspergillus fumigatus galactomannan, PLoS ONE 2018;13(3):e0193938.
2018Glycosylphosphatidylinositol Anchors from Galactomannan and GPI-Anchored Protein Are Synthesized by Distinct Pathways in Aspergillus fumigatus, J Fungi (Basel) 2018 Feb;4(1).
2017Aspergillus fumigatus Cell Wall α-(1,3)-Glucan Stimulates Regulatory T-Cell Polarization by Inducing PD-L1 Expression on Human Dendritic Cells, J. Infect. Dis. 2017 12;216(10):1281-1294.
2017Sphingolipids from the human fungal pathogen Aspergillus fumigatus, Biochimie 2017 Oct;141:9-15.
2017First Report of CD4 Lymphopenia and Defective Neutrophil Functions in a Patient with Amebiasis Associated with CMV Reactivation and Severe Bacterial and Fungal Infections, Front Microbiol 2017;8:203.
2016Biosynthesis of cell wall mannan in the conidium and the mycelium of Aspergillus fumigatus, Cell. Microbiol. 2016 Dec;18(12):1881-1891.
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