Sophie Bachellier-Bassi is a research assistant at Institut Pasteur. She obtained her PhD at Institut Pasteur, working on bacterial repetitive sequences, with Prof. Maurice Hofnung and Prof. Eric Gilson. She performed her post-doctoral training at the Dundee University (UK) with Prof. David Lilley. There, she studied the regulation of transcription by supercoiling in Escherichia coli. She then went on studying the baker’s yeast condensing complex with Dr. Ulf Nehrbass at Institut Pasteur. She joined the lab of Prof. Christophe d’Enfert in 2009 to study morphogenesis regulation pathways as well as biofilm formation in the pathogenic yeast Candida albicans. Sophie Bachellier-Bassi has been “Head of practical studies” at the Institut Pasteur course “Molecular Genetics and Epigenetics” since 2010.
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2021Regulators of commensal and pathogenic life-styles of an opportunistic fungus-Candida albicans., Yeast 2021 04; 38(4): 243-250.
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2021Involvement of amyloid proteins in the formation of biofilms in the pathogenic yeast Candida albicans., Res Microbiol 2021 Jan; (): 103813.
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2020A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224.
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2019The Candida albicans biofilm gene circuit modulated at the chromatin level by a recent molecular histone innovation, PLoS Biol. 2019 Aug;17(8):e3000422.
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2019Biofilms Are Generally Devoid of Persister Cells, Antimicrob. Agents Chemother. 2019 May;63(5).
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2019From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis., Curr Top Microbiol Immunol 2019 ; 422(): 61-99.
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2018Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut., Cell Microbiol 2018 Nov; 20(11): e12890.
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2018Generating genomic platforms to study Candida albicans pathogenesis., Nucleic Acids Res 2018 08; 46(14): 6935-6949.
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2017The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation., Mol Microbiol 2017 Oct; 106(1): 157-182.
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2014Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes, PLoS Pathog. 2014 Jun;10(6):e1004211.
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