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© Research

About

Sophie Bachellier-Bassi is a research assistant at Institut Pasteur. She obtained her PhD at Institut Pasteur, working on bacterial repetitive sequences, with Prof. Maurice Hofnung and Prof. Eric Gilson. She performed her post-doctoral training at the Dundee University (UK) with Prof. David Lilley. There, she studied the regulation of transcription by supercoiling in Escherichia coli. She then went on studying the baker’s yeast condensing complex with Dr. Ulf Nehrbass at Institut Pasteur. She joined the lab of Prof. Christophe d’Enfert in 2009 to study morphogenesis regulation pathways as well as biofilm formation in the pathogenic yeast Candida albicans. Sophie Bachellier-Bassi has been “Head of practical studies” at the Institut Pasteur course “Molecular Genetics and Epigenetics” since 2010.

Projects

Project
Ongoing
2 Members

HelPath

Sophie Bachellier-Bassi (PI)

This project aims at understanding the molecular basis of Candida albicans oscillatory hyphal growth. In collaboration with the teams of Catherine Villard at Université Paris Cité and Igor Kulic at the Institute Charles Sadron […]
Project
Completed
9 Members

A personal database system for large scale quantitative results exploration (Cassandre, PTR 463)

Christophe Malabat (PI)

Cassandre is a project of personal database system, integrating a “user-friendly” interface to manage and explore multiple sets of large-scale experimental results in biology. Large-scale experiments that generate quantitative data, such as changes in […]
Project
Ongoing
10 Members

Candida albicans colonization of abiotic and biotic surfaces

Christophe D’Enfert (PI)

Biofilms formed by C. albicans on indwelling devices play a major role in the persistence of nosocomial infections, largely because of their elevated tolerance to antifungals. The Fungal Biology and Pathogenicity Unit at Institut […]
Project
Ongoing
5 Members

Regulation of Candida albicans morphogenesis

Christophe D’Enfert (PI)

The Fungal Biology and Pathogenicity Unit at Institut Pasteur is interested in the regulation of the yeast-to-hypha transition in C. albicans because of its role in biofilm formation and, more generally, in virulence. While […]
Project
Ongoing
5 Members

CANDIHUB

Christophe D’Enfert (PI)

Candida albicans and Candida glabrata are the two major yeast species responsible for invasive fungal infections in humans. Systemic infections due to C. albicans and C. glabrata are associated with high mortality rates despite […]

Publications

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