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About

Simon Cauchemez joined Institut Pasteur in 2013 to head the new Mathematical Modelling of Infectious Diseases Unit. The main research objective of his unit is to develop state-of-the-art statistical and mathematical methods to address these challenges, with the aim to increase the understanding of how pathogens spread in human populations as well as the impact of interventions, to support policy making and optimize control strategies. His approach is therefore highly multidisciplinary, looking at infectious diseases through multiple perspectives (statistics, modelling, epidemiology, surveillance, Public Health, policy making, microbiology), multiple scales and multiple data streams. Before joining Institut Pasteur, Simon Cauchemez was working in the Department of Infectious Disease Epidemiology at Imperial College London.

Selected publications:

  • Andronico A, Dorléans F, Fergé JL, Salje H, Ghawché F, Signate A, Daudens-Vaysse E, Baudouin L, Dub T, Aubry M, Cao-Lormeau VM, Ledrans M, Noel H, Mallet HP, Fontanet A, Cabié A, Cauchemez S. Real-Time Assessment of Health-Care Requirements During the Zika Virus Epidemic in Martinique. American Journal of Epidemiology 2017; early publication.
  • Nikolay N, Salje H, Sturm-Ramirez K, Azziz-Baumgartner E, Homaira N, Ahmed M, Iuliano AD, Paul RC, Rahman M, Hossain MJ, Luby SP, Cauchemez S*, Gurley E*. Evaluating hospital-based surveillance for outbreak detection in Bangladesh: analysis of healthcare utilization data. PLoS Medicine 2017; 14:e1002218. *: Equal contribution.
  • Kraemer MUG, Faria NR, Reiner Jr RC, Golding N, Nikolay B, Stasse S, Johansson MA, Salje H, Faye O, Wint GRW, Niedrig M, Shearer FM, Hill SC, Thompson RN, Bisanzio D, Taveira N, Nax HH, Pradelski BSR, Nsoesie EO, Murphy NR, Bogoch II, Khan K, Brownstein JS, Tatem AJ, de Oliveira , Smith DL, Sall A, Pybus OG, Hay SI, Cauchemez S. Spread of Yellow Fever Virus outbreak in Angola and the Democratic Republic Congo 2015-2016: a modelling study. Lancet Infectious Diseases 2016; published online.
  • Salje H, Lessler J, Paul KK, Azman AS, Rahman MW, Rahman M, Cummings D, Gurley ES, Cauchemez S. How social structures, space and behaviours shape the spread of infectious diseases using chikungunya as a case study. PNAS 2016; 113:13420-13425.
  • Cauchemez S, Nouvellet P, Cori A, Jombart T, Garske T, Clapham H, Moore S, Mills HL, Salje H, Collins C, Rodriquez-Barraquer I, Riley S, Truelove S, Algarni H, Hakkeem R, AlHarbi K, Turkistani A, Aguas R, Cummings D, Van Kerkhove MD, Donnelly C, Lessler J, Fraser C, Al-Barrak A, Ferguson Unravelling the drivers of MERS-CoV transmission. PNAS 2016; 113:9081-9086.
  • Cauchemez S, Besnard M, Bompard P, Dub T, Guillmette-Arthur P, Eyrolle-Guignot D, Salje H, Van Kerkhove MD, Abadie V, Garel C, Fontanet A, Mallet HP. Association between Zika virus and microcephaly in French Polynesia, 2013-2015: a retrospective study. The Lancet 2016; 387:2125-32.
  • Faye O, Boëlle PY, Heleze E, Faye O, Loucoubar C, Magassouba NF, Soropogui B, Keita S, Gakou T, Bah EHI, Koivogui, Sall AA, Cauchemez S. Chains of transmission and control of Ebola virus disease in Conakry, Guinea, in 2014: an observational study. Lancet Infectious Diseases 2015; 15: 320-326.
  • Churcher TS, Cohen JM, Novotny J, Ntshalintshali N, Kunene S, Cauchemez S. Measuring the path toward malaria elimination. Science 2014; 1230: 1230-1232.
  • Cauchemez S, Ferguson NM, Fox A, Mai LQ, Thanh LT, Thai PQ, Thoang DD, Duong TN, Hoa LNM, Hien NT, Horby P. Determinants of influenza transmission in South East Asia: Insights from a household cohort study in Vietnam. PLoS Pathogens 2014; 10(8) : e1004310.
  • Cauchemez S, Fraser C, Van Kherkove M, Donnelly C, Riley S, Rambaut A, Enouf V, van der Werf S, Ferguson NM. Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility. Lancet Infectious Diseases 2014; 1:50-56.
  • Cauchemez S, Epperson S, Biggerstaff M, Swerdlow D, Finelli L, Ferguson NM. Using Routine Surveillance Data to Estimate the Epidemic Potential of Emerging Zoonoses: Application to the Emergence of US Swine Origin Influenza A H3N2v Virus. Plos Med 2013; e1001399.
  • Dorigatti I, Cauchemez S, Ferguson NM. Increased transmissibility explains the third wave of infection by the 2009 H1N1 pandemic virus in England. PNAS 2013 ; 110 :13422-7.
  • Cori A, Ferguson NM, Fraser C, Cauchemez S. A new framework and software to estimate time-varying reproduction numbers during epidemics. American Journal of Epidemiology 2013; 178: 1505-1512.
  • Cauchemez S, Horby P, Fox A, Le Quynh M, Le Thi T et al. Influenza infection rates, measurement errors and the interpretation of paired serology. PLoS Pathogens 2012; 8(12): e1003061.
  • Cauchemez S, Bhattarai A, Marchbanks TL, Fagan RP, Ostroff S, Ferguson NM, Swerdlow D, and the Pennsylvania H1N1 working group. Role of social networks in shaping disease transmission during a community outbreak of 2009 H1N1 pandemic influenza. PNAS 2011; 108:2825-2830.
  • Cauchemez S, Donnelly CA, Reed C, Ghani AC, Fraser C, Kent CK, Finelli L, Ferguson NM. Household Transmission of 2009 Pandemic H1N1 influenza virus in the United States. New England Journal of Medicine 2009; 361:2619-27.
  • Cauchemez S, Ferguson NM, Wachtel C, Tegnell A, Saour G, Duncan B, Nicoll A. Closing schools during a pandemic: a review. Lancet Infectious Disease 2009; 9:473-81.
  • Lipsitch M, Riley S, Cauchemez S, Ghani AC, Ferguson NM. Managing and reducing uncertainty in an emerging influenza pandemic. New England Journal of Medicine2009; 361:112-115.
  • Fraser C*, Donnelly CA*, Cauchemez S, Hanage WP, Van Kerkhove MD, Hollingsworth TD, Griffin J, Baggaley RF et al. Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings. Science 2009; 324:1557-1561. * Equal contribution.
  • Cauchemez S, Valleron AJ, Boelle PY, Flahault A, Ferguson NM. Estimating the impact of school closure on influenza transmission from sentinel data. Nature 2008; 452:750-754.
  • Cauchemez S, Temime L, Guillemot D, Varon E, Valleron AJ, Thomas G, Boëlle PY. Investigating heterogeneity in pneumococcal transmission: A Bayesian MCMC approach applied to a follow-up of schools. Journal of the American Statistical Association 2006; 101: 946-214.
  • Ferguson NM, Cummings D, Cauchemez S, Fraser C, Riley S, Meeyai A, Iamsirithaworn S, Burke D. Strategies for containing an emerging influenza pandemic in SE Asia. Nature 2005; 437: 209-214.

Courses

09:00
30
Oct 2016
Course

Introduction to Modeling of Infectious Diseases

DATE: October 30-November 4, 2016 VENUE: Training Center Pasteur Institute in Ho Chi Minh City Ho Chi Minh City, Vietnam COURSE FACULTY: Marc LIPSITCH Harvard TH Chan School of Public Health, Boston Mark JIT […]
Institut Pasteur in Ho Chi Minh City [Vietnam]
Hong Kong University-Pasteur Research Centre
Simon Cauchemez
2016-10-30 09:00:00 2016-11-04 18:00:00 Europe/Paris Introduction to Modeling of Infectious Diseases DATE: October 30-November 4, 2016 VENUE: Training Center Pasteur Institute in Ho Chi Minh City Ho Chi Minh City, Vietnam COURSE FACULTY: Marc LIPSITCH Harvard TH Chan School of Public Health, Boston Mark JIT […] Viện Pasteur, Pasteur, Ho Chi Minh City, Hô Chi Minh, Vietnam

Projects

project
Ongoing
3 Members

Improved understanding of patterns of arbovirus infection risk

Henrik Salje (PI)

There have been a number of recent efforts to build global maps of infection risk for different pathogens. These maps typically use the results of regressions in well-characterized settings to quantify the association between […]
project
Ongoing
13 Members

Emergency response to global threats of emerging and re-emerging pathogens

Maria Van Kerkhove (PI)

With over 125 years’ experience with infectious diseases, the Institut Pasteur and the Institut Pasteur International Network (IPIN), which is composed of 33 research institutes in 26 countries and five continents, are ideally positioned […]
project
Ongoing
5 Members

Modelling the dynamics of infection within the host

Simon Cauchemez (PI)

  A large number of groups at the Institut Pasteur perform state-of-the-art research documenting the dynamics of infection in vivo for a variety of pathogens. These dynamics are often complex and the data may […]
project
Ongoing
7 Members

Assessing the threat posed by zoonotic viruses like MERS-CoV, Nipah or avian influenza

Simon Cauchemez (PI)

Zoonotic viruses are viruses that have an animal reservoir but may also infect humans. The 2009 A(H1N1)pdm09 influenza pandemic, the SARS epidemic in 2003, the recent emergence of a novel coronavirus in the Middle […]
project
Completed
2 Members

Measuring the path towards malaria elimination

Simon Cauchemez (PI)

The fight against malaria has been declared a Millennium Development Goal by the World Health Organization, and as such receives significant worldwide funding. Despite this fact, the public health agencies that manage this program […]
project
Completed
2 Members

Chikungunya in the Americas

Simon Cauchemez (PI)

An outbreak of chikungunya fever started in the Americas at the end of 2013. Figure 1 below shows territories that reported at least one autochthonous case by 15 June 2014. The first territory reporting […]
project
Completed
6 Members

Epidemiologic assessment and modelling of the epidemic of Ebola in West Africa

Simon Cauchemez (PI)

West Africa has been affected by an epidemic of Ebola of unprecedented magnitude. Since summer 2014, we have been working very closely with Amadou Sall and his team from Institut Pasteur Dakar and a […]

Publications