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Projets
CV
(EN)
EDUCATION
- 2015 – Expérimentation animale, concepteur de projets
- 2002 – DEPHE, mention très bien, validation Master 2, Sorbonne Paris, France
- 1988 – DPCT biochimie/biologie, CNAM Paris, France
- 1981 – Bac F7 biochimie, Cachan, France
RESEARCH and Professional EXPERIENCE
- 2008-present – Ingénieure de recherche confirmée, Institut Pasteur, Paris, France
- 1983-2008 – Technicienne, Institut Pasteur, Paris, France
SCIENTIFIC ACTIVITIES
- 30 publications, 3 oral presentations and 10 posters in international congresses – Hirsch h index:13
- Co-organization of 2 departmental retreats Co-coordinator of the LeiSHield-MATI – RISE – H-2020 project Reviewer for PLOS Neglected Tropical diseases
TEACHING ACTIVITIES
- 1 thesis (Leishmania virulence) currently in co-supervision
- Teaching in masters formations at the Institut Pasteur
- Teaching/supervision of researchers, Masters and graduate students
ADMINISTRATIVE RESPONSIBILITIES and EXPERTISE
- From 2013 to 2017, member of the COMESP (scientific evaluation committee) of the Institut Pasteur.
- Scientific responsible of the ‘laboratoire de préparation’
- Correspondent for the animal facility
- Since 2014 designer and responsible for animal experimentation for the unit
- Member of the Biomics committee users for the PIV department
- Member of the MSBio committee users
Publications
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2018Reverse Epidemiology: An Experimental Framework to Drive Biomarker Discovery by Functional Genetic Screening Using Relevant Animal Models, Front Cell Infect Microbiol 2018;8:325.
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2018Stage-specific expression of the proline-alanine transporter in the human pathogen Leishmania, Mol. Biochem. Parasitol. 2018 06;222:1-5.
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2017Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani, Nat Ecol Evol 2017 Dec;1(12):1961-1969.
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2017New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence, PLoS Negl Trop Dis 2017 09;11(9):e0005924.
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2017Modulation of Aneuploidy in during Adaptation to Different and Environments and Its Impact on Gene Expression, mBio 2017 05;8(3).
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2016Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant, J. Eukaryot. Microbiol. 2016 11;63(6):823-833.
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2013Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection, Antimicrob. Agents Chemother. 2014;58(3):1501-15.
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2011Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery, PLoS ONE 2011;6(7):e22463.
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2011Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation, Cell. Microbiol. 2011 Jul;13(7):978-91.
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2011Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process, Cell Host Microbe 2011 Apr;9(4):319-30.
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