Timeline
Pascale Pescher
Research Engineer
07 Mar 2023
publication
Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage.
Read more01 Jan 2023
publication
Amphotericin B resistance correlates with increased fitness in vitro and in vivo in Leishmania (Mundinia) martiniquensis.
Read more01 Mar 2022
publication
Experimental evolution links post-transcriptional regulation to Leishmania fitness gain.
Read more10 Feb 2022
project
PTR 425 EvoLeish: Mapping mechanisms of evolutionary adaptation underlying fitness gain in New World L. infantum strains
Read more21 Dec 2021
publication
Genome instability drives epistatic adaptation in the human pathogen Leishmania.
Read more22 Jun 2020
publication
Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages.
Read more20 Feb 2020
publication
SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.
Read more24 Jan 2019
16 Jan 2019
project
“Modelling and functional analysis of clonal Evolution in Leishmania – possible role of non-coding RNAs and RNA modification”
Read more12 Apr 2018
publication
Stage-specific expression of the proline-alanine transporter in the human pathogen Leishmania
Read more01 Jan 2018
publication
Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models.
Read more06 Nov 2017
publication
Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani
Read more25 Sep 2017
publication
New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence
Read more23 May 2017
publication
Modulation of Aneuploidy in during Adaptation to Different and Environments and Its Impact on Gene Expression
Read more16 Jun 2016
publication
Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant
Read more14 Sep 2015
07 Sep 2015
project
LeiSHield – A new collaborative action to determine prevalence, anticipate emergence and assess urbanization of cutaneous and visceral leishmaniasis in LeishRIIP partner countries
Read more11 May 2015
01 Jan 2014
publication
Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.
Read more21 Jul 2011
publication
Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery
Read more26 Apr 2011
publication
Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation
Read more21 Apr 2011
publication
Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process
Read more01 Nov 2010
publication
Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses
Read more23 Jul 2009
publication
A dynamic map of antigen recognition by CD4 T cells at the site of Leishmania major infection
Read more01 Jun 2005
publication
In vivo efficiency of targeted norfloxacin against persistent, isoniazid-insensitive, Mycobacterium bovis BCG present in the physiologically hypoxic mouse liver
Read more03 Jan 2005
publication
Targeted norfloxacin is active in vivo against persistent Mycobacterium bovis BCG
Read more01 Oct 2003
publication
Enhanced cloning efficiency of mouse bone marrow macrophage progenitors correlates with increased content of CSF-1 receptor of their progeny at low oxygen tension
Read more01 Jan 2003
publication
Characterization of a putative type IV aminophospholipid transporter P-type ATPase
Read more01 Nov 2002
publication
[Preliminary study on isoniazid-epiroprim combination in a tuberculosis murine model]
Read more06 Apr 2001
publication
Mixed immune response induced in rodents by two naked DNA genes coding for mycobacterial glycosylated proteins
Read more01 Jan 2001
01 Nov 1999
publication
Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responses
Read more16 Oct 1996
publication
Characterization of murine monoclonal antibodies specific for the 45/47 kDa antigen complex (APA) of Mycobacterium tuberculosis, M. bovis and BCG
Read more01 Jun 1993
publication
Isolation of a proline-rich mycobacterial protein eliciting delayed-type hypersensitivity reactions only in guinea pigs immunized with living mycobacteria
Read more01 Feb 1993
publication
Identification of a Mycobacterium bovis BCG 45/47-kilodalton antigen complex, an immunodominant target for antibody response after immunization with living bacteria
Read more01 Sep 1985