Viral Host Range database
The Viral Host Range database (VHRdb) represents a unique resource for the community to rapidly find, document analyze and disseminate data related to the range of hosts that a virus can infect. Over the […]
Bacteriophage gene expression by RNA-Seq
Analyses of RNA-Seq data from two related virulent bacteriophages, PAK_P3 and PAK_P4 infecting the bacterium Pseudomonas aeruginosa.
Molecular characterization of therapeutic bacteriophages
Bacteriophages infecting pathogenic bacteria, which have been studied for their in vivo activities and defined as valuable for therapeutic application, are in this project, subject to molecular studies ranging from bacterial receptor identification to […]
Treatment of pulmonary infections
Pulmonary infections are a leading cause of death worldwide and infections caused by antibiotic-resistant bacteria are steadily increasing. We study how virulent bacteriophages can be used to treat bacterial lung infections. We develop infectious […]
Virulents bacteriophages and microbial ecosystems
Digestive tract of mammals is one of the most complex microbial ecosystems subject to both external and internal factors, through food consumption and interactions with intestinal cells. We are developing and using several experimental […]
De novo assembly for integration into MicroScope/MaGe platform
To perform the assembly of a bacterial genome from Illumina sequencing in order to submit it to the MicroScope/MaGe platform of Genoscope.
16S rDNA data analysis
To perform assignment of 16S sequences to bacterial genera and statistical analysis of variations of bacterial populations collected from mice feces
2022Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy., Cell Rep 2022 May; 39(7): 110825.
2022The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection., Cell Host Microbe 2022 04; 30(4): 556-569.e5.
2021The intestinal virome: lessons from animal models., Curr Opin Virol 2021 Oct; 51(): 141-148.
2021Intestinal Bacteriophage Therapy: Looking for Optimal Efficacy., Clin Microbiol Rev 2021 Oct; (): e0013621.
2021Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden in Vivo., Microbiol Spectr 2021 Sep; 9(1): e0049721.
2021Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community., Microbiol Resour Announc 2021 Apr; 10(17): .
2021Viral Host Range database, an online tool for recording, analyzing and disseminating virus-host interactions., Bioinformatics 2021 Feb; (): .
2020The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages., Cell Host Microbe 2020 09; 28(3): 390-401.e5.
2020Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage., Science 2020 08; 369(6506): 936-942.
2020Isolation and Characterization of Bacteriophages That Infect Citrobacter rodentium, a Model Pathogen for Intestinal Diseases, Viruses 2020 Jul; 12(7):E737.
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