Laurent Debarbieux

Analyses of RNA-Seq data from two related virulent bacteriophages, PAK_P3 and PAK_P4 infecting the bacterium Pseudomonas aeruginosa.

Bacteriophages infecting pathogenic bacteria, which have been studied for their in vivo activities and defined as valuable for therapeutic application, are in this project, subject to molecular studies ranging from bacterial receptor identification to […]

Pulmonary infections are a leading cause of death worldwide and infections caused by antibiotic-resistant bacteria are steadily increasing. We study how virulent bacteriophages can be used to treat bacterial lung infections. We develop infectious […]

Digestive tract of mammals is one of the most complex microbial ecosystems subject to both external and internal factors, through food consumption and interactions with intestinal cells. We are developing and using several experimental […]

To perform the assembly of a bacterial genome from Illumina sequencing in order to submit it to the MicroScope/MaGe platform of Genoscope.

To perform assignment of 16S sequences to bacterial genera and statistical analysis of variations of bacterial populations collected from mice feces

The goal of this project is to set sequence analysis tools to evaluate the frequency of mutations within a pool of bacteriophage genomes sequenced by NGS.