Viral Host Range database
The Viral Host Range database (VHRdb) represents a unique resource for the community to rapidly find, document analyze and disseminate data related to the range of hosts that a virus can infect. Over the […]
Bacteriophage gene expression by RNA-Seq
Analyses of RNA-Seq data from two related virulent bacteriophages, PAK_P3 and PAK_P4 infecting the bacterium Pseudomonas aeruginosa.
Molecular characterization of therapeutic bacteriophages
Bacteriophages infecting pathogenic bacteria, which have been studied for their in vivo activities and defined as valuable for therapeutic application, are in this project, subject to molecular studies ranging from bacterial receptor identification to […]
Treatment of pulmonary infections
Pulmonary infections are a leading cause of death worldwide and infections caused by antibiotic-resistant bacteria are steadily increasing. We study how virulent bacteriophages can be used to treat bacterial lung infections. We develop infectious […]
Virulents bacteriophages and microbial ecosystems
Digestive tract of mammals is one of the most complex microbial ecosystems subject to both external and internal factors, through food consumption and interactions with intestinal cells. We are developing and using several experimental […]
De novo assembly for integration into MicroScope/MaGe platform
To perform the assembly of a bacterial genome from Illumina sequencing in order to submit it to the MicroScope/MaGe platform of Genoscope.
16S rDNA data analysis
To perform assignment of 16S sequences to bacterial genera and statistical analysis of variations of bacterial populations collected from mice feces
2023Human Neutrophil Response to Pseudomonas Bacteriophage PAK_P1, a Therapeutic Candidate., Viruses 2023 Aug; 15(8): .
2023Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice., PLoS Pathog 2023 Aug; 19(8): e1011600.
2023Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria., Microbiome 2023 May; 11(1): 111.
2022The role of the animal host in the management of bacteriophage resistance during phage therapy., Curr Opin Virol 2022 Dec; 58(): 101290.
2022The Selection of Antibiotic- and Bacteriophage-Resistant Pseudomonas aeruginosa Is Prevented by Their Combination., Microbiol Spectr 2022 Oct; 10(5): e0287422.
2022Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy., Cell Rep 2022 May; 39(7): 110825.
2022The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection., Cell Host Microbe 2022 04; 30(4): 556-569.e5.
2021The intestinal virome: lessons from animal models., Curr Opin Virol 2021 Oct; 51(): 141-148.
2021Intestinal Bacteriophage Therapy: Looking for Optimal Efficacy., Clin Microbiol Rev 2021 Oct; (): e0013621.
2021Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden in Vivo., Microbiol Spectr 2021 Sep; 9(1): e0049721.
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