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  • Veterinary
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  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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About

We use NMR combined with other biophysical and biochemical techniques to study the structure and the mechanism of self-assembly of functional amyloids formed by Aspergillus fumigatus hydrophobins.

SynopsisWe are also interested on the interactions of hydrophobins with the major components of the fungal cell wall.

Projects

Project
Completed
2 Members

Hydrophobin: functional amyloids from the fungal pathogen Aspergillus fumigatus

Iñaki Guijarro (PI)

Proteins from the hydrophobin family are produced by filamentous fungi in a soluble form, which spontaneously self-assemble at air/water or hydrophobic/hydrophilic interfaces to produce amphipathic layers and accomplish their biological role. Hydrophobin layers consist […]
Project
Ongoing
8 Members

Biophysical characterization of the translocation process of Bordetella pertussis adenylate cyclase toxin CyaA

Alexandre Chenal (PI)

This project aims to describe the hydrodynamic and thermodynamic properties of the CyaA toxin and the conformational changes it undergoes during its translocation process across the lipid membranes of Bordetella pertussis (secretion) and of […]
Project
Ongoing
3 Members

Functional amyloids of the cell wall of the fungal pathogen Aspergillus fumigatus

Iñaki Guijarro (PI)

Aspergillus fumigatus is an opportunistic pathogen than can cause a variety of diseases in immunocompromised individuals that range from allergies to severe pathologies such as invasive aspergillosis. This filamentous fungus has become the major […]

Publications

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